Table of Contents

Volume 23, Number 20
13 October 2004
pp 3909-4125
Points of View by Benedict Rubbra. Oil on canvas, 140 x 120 cm. The painting is an interpretation of the work of the scientist Frances Ashcroft on insulin secretion. Frances Ashcroft is the Royal Society�s GlaxoSmithKline Research Professor and works at the University Laboratory of Physiology, Oxford UK. Her laboratory studies the role of the ATP-sensitive potassium channel in insulin secretion from pancreatic beta-cells. Benedict Rubbra�s sojourn in her laboratory resulted in a collaborative exhibition, Points of View, about the differences and similarities in the way artist and scientist view the world. The exhibition was shown in Oxford, Cambridge and London. For further information about the artist's work please contact him at benrubbra@aol.com
Articles
Top of pageCrystal structure of human GGA1 GAT domain complexed with the GAT-binding domain of Rabaptin5 FREE
The EMBO Journal (2004), 23, - 3909 - 3917, doi:10.1038/sj.emboj.7600411
- Abstract - Crystal structure of human GGA1 GAT domain complexed with the GAT-binding domain of Rabaptin5
- Full text
- PDF (375 KB) - Crystal structure of human GGA1 GAT domain complexed with the GAT-binding domain of Rabaptin5
- Supplementary information
Published online: 30 September 2004
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Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates FREE
The EMBO Journal (2004), 23, - 3918 - 3928, doi:10.1038/sj.emboj.7600379
- Abstract - Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates
- Full text
- PDF (550 KB) - Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates
- Supplementary information
Published online: 30 September 2004
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Structural basis for recognition of 2',5'-linked oligoadenylates by human ribonuclease L FREE
The EMBO Journal (2004), 23, - 3929 - 3938, doi:10.1038/sj.emboj.7600420
- Abstract - Structural basis for recognition of 2[prime],5[prime]-linked oligoadenylates by human ribonuclease L
- Full text
- PDF (588 KB) - Structural basis for recognition of 2[prime],5[prime]-linked oligoadenylates by human ribonuclease L
Published online: 23 September 2004
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Multiple SNARE interactions of an SM protein: Sed5p/Sly1p binding is dispensable for transport FREE
The EMBO Journal (2004), 23, - 3939 - 3949, doi:10.1038/sj.emboj.7600410
- Abstract - Multiple SNARE interactions of an SM protein: Sed5p/Sly1p binding is dispensable for transport
- Full text
- PDF (501 KB) - Multiple SNARE interactions of an SM protein: Sed5p/Sly1p binding is dispensable for transport
Published online: 16 September 2004
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Receptor activity-independent recruitment of
arrestin2 reveals specific signalling modes
FREE The EMBO Journal (2004), 23, - 3950 - 3961, doi:10.1038/sj.emboj.7600387
- Abstract - Receptor activity-independent recruitment of [beta]arrestin2 reveals specific signalling modes
- Full text
- PDF (371 KB) - Receptor activity-independent recruitment of [beta]arrestin2 reveals specific signalling modes
- Supplementary information
Published online: 23 September 2004
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Coordinating assembly and export of complex bacterial proteins FREE
The EMBO Journal (2004), 23, - 3962 - 3972, doi:10.1038/sj.emboj.7600409
- Abstract - Coordinating assembly and export of complex bacterial proteins
- Full text
- PDF (258 KB) - Coordinating assembly and export of complex bacterial proteins
Published online: 23 September 2004
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Mutant actins that stabilise F-actin use distinct mechanisms to activate the SRF coactivator MAL FREE
The EMBO Journal (2004), 23, - 3973 - 3983, doi:10.1038/sj.emboj.7600404
- Abstract - Mutant actins that stabilise F-actin use distinct mechanisms to activate the SRF coactivator MAL
- Full text
- PDF (468 KB) - Mutant actins that stabilise F-actin use distinct mechanisms to activate the SRF coactivator MAL
- Supplementary information
Published online: 23 September 2004
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PVR plays a critical role via JNK activation in thorax closure during Drosophila metamorphosis FREE
The EMBO Journal (2004), 23, - 3984 - 3994, doi:10.1038/sj.emboj.7600417
- Abstract - PVR plays a critical role via JNK activation in thorax closure during : Drosophila: metamorphosis
- Full text
- PDF (341 KB) - PVR plays a critical role via JNK activation in thorax closure during : Drosophila: metamorphosis
- Supplementary information
Published online: 30 September 2004
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PIKE/nuclear PI 3-kinase signaling mediates the antiapoptotic actions of NGF in the nucleus FREE
The EMBO Journal (2004), 23, - 3995 - 4006, doi:10.1038/sj.emboj.7600392
- Abstract - PIKE/nuclear PI 3-kinase signaling mediates the antiapoptotic actions of NGF in the nucleus
- Full text
- PDF (546 KB) - PIKE/nuclear PI 3-kinase signaling mediates the antiapoptotic actions of NGF in the nucleus
Published online: 23 September 2004
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An important role of phospholipase C
1 in pre-B-cell development and allelic exclusion
FREE The EMBO Journal (2004), 23, - 4007 - 4017, doi:10.1038/sj.emboj.7600405
- Abstract - An important role of phospholipase C[gamma]1 in pre-B-cell development and allelic exclusion
- Full text
- PDF (416 KB) - An important role of phospholipase C[gamma]1 in pre-B-cell development and allelic exclusion
- Supplementary information
Published online: 16 September 2004
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Endoglin promotes endothelial cell proliferation and TGF-
/ALK1 signal transduction
FREE The EMBO Journal (2004), 23, - 4018 - 4028, doi:10.1038/sj.emboj.7600386
- Abstract - Endoglin promotes endothelial cell proliferation and TGF-[beta]/ALK1 signal transduction
- Full text
- PDF (507 KB) - Endoglin promotes endothelial cell proliferation and TGF-[beta]/ALK1 signal transduction
Published online: 23 September 2004
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ACF1 improves the effectiveness of nucleosome mobilization by ISWI through PHD–histone contacts FREE
The EMBO Journal (2004), 23, - 4029 - 4039, doi:10.1038/sj.emboj.7600382
- Abstract - ACF1 improves the effectiveness of nucleosome mobilization by ISWI through PHD-histone contacts
- Full text
- PDF (301 KB) - ACF1 improves the effectiveness of nucleosome mobilization by ISWI through PHD-histone contacts
Published online: 30 September 2004
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Targeting of Swi/Snf to the yeast GAL1 UASG requires the Mediator, TAFIIs, and RNA polymerase II FREE
The EMBO Journal (2004), 23, - 4040 - 4050, doi:10.1038/sj.emboj.7600416
- Abstract - Targeting of Swi/Snf to the yeast : GAL1: UAS: G: requires the Mediator, TAF: II: s, and RNA polymerase II
- Full text
- PDF (459 KB) - Targeting of Swi/Snf to the yeast : GAL1: UAS: G: requires the Mediator, TAF: II: s, and RNA polymerase II
- Supplementary information
Published online: 23 September 2004
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MicroRNA genes are transcribed by RNA polymerase II FREE
The EMBO Journal (2004), 23, - 4051 - 4060, doi:10.1038/sj.emboj.7600385
- Abstract - MicroRNA genes are transcribed by RNA polymerase II
- Full text
- PDF (227 KB) - MicroRNA genes are transcribed by RNA polymerase II
- Supplementary information
Published online: 16 September 2004
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Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity FREE
The EMBO Journal (2004), 23, - 4061 - 4071, doi:10.1038/sj.emboj.7600402
- Abstract - Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity
- Full text
- PDF (424 KB) - Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity
- Supplementary information
Published online: 23 September 2004
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Cell-line-induced mutation of the rotavirus genome alters expression of an IRF3-interacting protein FREE
The EMBO Journal (2004), 23, - 4072 - 4081, doi:10.1038/sj.emboj.7600408
- Abstract - Cell-line-induced mutation of the rotavirus genome alters expression of an IRF3-interacting protein
- Full text
- PDF (296 KB) - Cell-line-induced mutation of the rotavirus genome alters expression of an IRF3-interacting protein
Published online: 16 September 2004
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Interference of human and Drosophila APP and APP-like proteins with PNS development in Drosophila FREE
The EMBO Journal (2004), 23, - 4082 - 4095, doi:10.1038/sj.emboj.7600413
- Abstract - Interference of human and : Drosophila: APP and APP-like proteins with PNS development in : Drosophila
- Full text
- PDF (821 KB) - Interference of human and : Drosophila: APP and APP-like proteins with PNS development in : Drosophila
- Supplementary information
Published online: 23 September 2004
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RAGE potentiates A
-induced perturbation of neuronal function in transgenic mice
FREE The EMBO Journal (2004), 23, - 4096 - 4105, doi:10.1038/sj.emboj.7600415
- Abstract - RAGE potentiates A[beta]-induced perturbation of neuronal function in transgenic mice
- Full text
- PDF (339 KB) - RAGE potentiates A[beta]-induced perturbation of neuronal function in transgenic mice
- Supplementary information
Published online: 30 September 2004
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Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members FREE
The EMBO Journal (2004), 23, - 4106 - 4115, doi:10.1038/sj.emboj.7600390
- Abstract - Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members
- Full text
- PDF (541 KB) - Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members
Published online: 23 September 2004
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Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells FREE
The EMBO Journal (2004), 23, - 4116 - 4125, doi:10.1038/sj.emboj.7600419
- Abstract - Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells
- Full text
- PDF (343 KB) - Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells
- Supplementary information
Published online: 23 September 2004
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