Table of Contents
Volume 22, Number 16
15 August 2003
pp 4027-4336
Cover. Tropical rain forest at Mt Kinabalu National Park, Malaysia. Tropical rain forests constitute rich biological resources for future generations and might well hold drugs to be discovered against many diseases. Freddy Frischknecht works at the Pasteur Institute on the cell biology of malaria parasites and hopes to establish novel screening methods that would enable the discovery of new drugs.
Articles
Top of pageCrystal structure and functional analysis of Escherichia coli glutamate decarboxylase FREE
The EMBO Journal (2003), 22, - 4027 - 4037, doi:10.1093/emboj/cdg403
- Abstract - Crystal structure and functional analysis of : Escherichia coli: glutamate decarboxylase
- Full text
- PDF (488 KB) - Crystal structure and functional analysis of : Escherichia coli: glutamate decarboxylase
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Channelling and formation of 'active' formaldehyde in dimethylglycine oxidase FREE
The EMBO Journal (2003), 22, - 4038 - 4048, doi:10.1093/emboj/cdg395
- Abstract - Channelling and formation of 'active' formaldehyde in dimethylglycine oxidase
- Full text
- PDF (559 KB) - Channelling and formation of 'active' formaldehyde in dimethylglycine oxidase
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Gain-of-function mutations indicate that Escherichia coli Kch forms a functional K+ conduit in vivo FREE
The EMBO Journal (2003), 22, - 4049 - 4058, doi:10.1093/emboj/cdg409
- Abstract - Gain-of-function mutations indicate that : Escherichia coli: Kch forms a functional K: +: conduit : in vivo
- Full text
- PDF (397 KB) - Gain-of-function mutations indicate that : Escherichia coli: Kch forms a functional K: +: conduit : in vivo
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Activation of phospholipase D by the small GTPase Sar1p is required to support COPII assembly and ER export FREE
The EMBO Journal (2003), 22, - 4059 - 4069, doi:10.1093/emboj/cdg390
- Abstract - Activation of phospholipase D by the small GTPase Sar1p is required to support COPII assembly and ER export
- Full text
- PDF (445 KB) - Activation of phospholipase D by the small GTPase Sar1p is required to support COPII assembly and ER export
- Supplementary information
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GCNF-dependent repression of BMP-15 and GDF-9 mediates gamete regulation of female fertility FREE
The EMBO Journal (2003), 22, - 4070 - 4081, doi:10.1093/emboj/cdg405
- Abstract - GCNF-dependent repression of : BMP-15: and : GDF-9: mediates gamete regulation of female fertility
- Full text
- PDF (702 KB) - GCNF-dependent repression of : BMP-15: and : GDF-9: mediates gamete regulation of female fertility
- Supplementary information
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HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1
in normoxia
FREE The EMBO Journal (2003), 22, - 4082 - 4090, doi:10.1093/emboj/cdg392
- Abstract - HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1[alpha] in normoxia
- Full text
- PDF (247 KB) - HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1[alpha] in normoxia
- Supplementary information
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Contrasting effects of VEGF gene disruption in embryonic stem cell-derived versus oncogene-induced tumors FREE
The EMBO Journal (2003), 22, - 4091 - 4102, doi:10.1093/emboj/cdg408
- Abstract - Contrasting effects of : VEGF: gene disruption in embryonic stem cell-derived versus oncogene-induced tumors
- Full text
- PDF (593 KB) - Contrasting effects of : VEGF: gene disruption in embryonic stem cell-derived versus oncogene-induced tumors
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A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling FREE
The EMBO Journal (2003), 22, - 4103 - 4110, doi:10.1093/emboj/cdg412
- Abstract - A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling
- Full text
- PDF (399 KB) - A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling
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Sequential recognition of two distinct sites in
S by the proteolytic targeting factor RssB and ClpX
FREE The EMBO Journal (2003), 22, - 4111 - 4120, doi:10.1093/emboj/cdg411
- Abstract - Sequential recognition of two distinct sites in [sigma]: S: by the proteolytic targeting factor RssB and ClpX
- Full text
- PDF (385 KB) - Sequential recognition of two distinct sites in [sigma]: S: by the proteolytic targeting factor RssB and ClpX
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Receptor protein tyrosine phosphatase
is essential for hippocampal neuronal migration and long-term potentiation
FREE The EMBO Journal (2003), 22, - 4121 - 4131, doi:10.1093/emboj/cdg399
- Abstract - Receptor protein tyrosine phosphatase [alpha] is essential for hippocampal neuronal migration and long-term potentiation
- Full text
- PDF (475 KB) - Receptor protein tyrosine phosphatase [alpha] is essential for hippocampal neuronal migration and long-term potentiation
- Supplementary information
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Interdimer processing mechanism of procaspase-8 activation FREE
The EMBO Journal (2003), 22, - 4132 - 4142, doi:10.1093/emboj/cdg414
- Abstract - Interdimer processing mechanism of procaspase-8 activation
- Full text
- PDF (437 KB) - Interdimer processing mechanism of procaspase-8 activation
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Focal adhesion kinase signaling promotes phagocytosis of integrin-bound photoreceptors FREE
The EMBO Journal (2003), 22, - 4143 - 4154, doi:10.1093/emboj/cdg416
- Abstract - Focal adhesion kinase signaling promotes phagocytosis of integrin-bound photoreceptors
- Full text
- PDF (671 KB) - Focal adhesion kinase signaling promotes phagocytosis of integrin-bound photoreceptors
- Supplementary information
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Pak1 and PIX regulate contact inhibition during epithelial wound healing FREE
The EMBO Journal (2003), 22, - 4155 - 4165, doi:10.1093/emboj/cdg398
- Abstract - Pak1 and PIX regulate contact inhibition during epithelial wound healing
- Full text
- PDF (656 KB) - Pak1 and PIX regulate contact inhibition during epithelial wound healing
- Supplementary information
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Differential regulation of NFAT and SRF by the B cell receptor via a PLC
–Ca2+-dependent pathway
FREE The EMBO Journal (2003), 22, - 4166 - 4177, doi:10.1093/emboj/cdg401
- Abstract - Differential regulation of NFAT and SRF by the B cell receptor via a PLC[gamma]-Ca: 2+: -dependent pathway
- Full text
- PDF (475 KB) - Differential regulation of NFAT and SRF by the B cell receptor via a PLC[gamma]-Ca: 2+: -dependent pathway
- Supplementary information
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Insulin induces phosphatidylinositol-3-phosphate formation through TC10 activation FREE
The EMBO Journal (2003), 22, - 4178 - 4189, doi:10.1093/emboj/cdg402
- Abstract - Insulin induces phosphatidylinositol-3-phosphate formation through TC10 activation
- Full text
- PDF (529 KB) - Insulin induces phosphatidylinositol-3-phosphate formation through TC10 activation
- Supplementary information
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The in vivo roles of STEF/Tiam1, Rac1 and JNK in cortical neuronal migration FREE
The EMBO Journal (2003), 22, - 4190 - 4201, doi:10.1093/emboj/cdg413
- Abstract - The : in vivo: roles of STEF/Tiam1, Rac1 and JNK in cortical neuronal migration
- Full text
- PDF (944 KB) - The : in vivo: roles of STEF/Tiam1, Rac1 and JNK in cortical neuronal migration
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In vivo role of the PIF-binding docking site of PDK1 defined by knock-in mutation FREE
The EMBO Journal (2003), 22, - 4202 - 4211, doi:10.1093/emboj/cdg407
- Abstract - In vivo: role of the PIF-binding docking site of PDK1 defined by knock-in mutation
- Full text
- PDF (332 KB) - In vivo: role of the PIF-binding docking site of PDK1 defined by knock-in mutation
- Supplementary information
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Reversal of human cellular senescence: roles of the p53 and p16 pathways FREE
The EMBO Journal (2003), 22, - 4212 - 4222, doi:10.1093/emboj/cdg417
- Abstract - Reversal of human cellular senescence: roles of the p53 and p16 pathways
- Full text
- PDF (401 KB) - Reversal of human cellular senescence: roles of the p53 and p16 pathways
- Supplementary information
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Regulation of PI4,5P2 synthesis by nuclear–cytoplasmic shuttling of the Mss4 lipid kinase FREE
The EMBO Journal (2003), 22, - 4223 - 4236, doi:10.1093/emboj/cdg397
- Abstract - Regulation of PI4,5P: 2: synthesis by nuclear-cytoplasmic shuttling of the Mss4 lipid kinase
- Full text
- PDF (517 KB) - Regulation of PI4,5P: 2: synthesis by nuclear-cytoplasmic shuttling of the Mss4 lipid kinase
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Distinct requirements for the naturally occurring splice forms Stat4
and Stat4
in IL-12 responses
FREE The EMBO Journal (2003), 22, - 4237 - 4248, doi:10.1093/emboj/cdg393
- Abstract - Distinct requirements for the naturally occurring splice forms Stat4[alpha] and Stat4[beta] in IL-12 responses
- Full text
- PDF (325 KB) - Distinct requirements for the naturally occurring splice forms Stat4[alpha] and Stat4[beta] in IL-12 responses
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Identification of the RNA polymerase II subunit hsRPB7 as a novel target of the von Hippel–Lindau protein FREE
The EMBO Journal (2003), 22, - 4249 - 4259, doi:10.1093/emboj/cdg410
- Abstract - Identification of the RNA polymerase II subunit hsRPB7 as a novel target of the von Hippel–Lindau protein
- Full text
- PDF (490 KB) - Identification of the RNA polymerase II subunit hsRPB7 as a novel target of the von Hippel–Lindau protein
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GATA-6 maintains BMP-4 and Nkx2 expression during cardiomyocyte precursor maturation FREE
The EMBO Journal (2003), 22, - 4260 - 4273, doi:10.1093/emboj/cdg400
- Abstract - GATA-6 maintains BMP-4 and Nkx2 expression during cardiomyocyte precursor maturation
- Full text
- PDF (514 KB) - GATA-6 maintains BMP-4 and Nkx2 expression during cardiomyocyte precursor maturation
- Supplementary information
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A 10 residue motif at the C-terminus of the RNA pol II CTD is required for transcription, splicing and 3' end processing FREE
The EMBO Journal (2003), 22, - 4274 - 4282, doi:10.1093/emboj/cdg396
- Abstract - A 10 residue motif at the C-terminus of the RNA pol II CTD is required for transcription, splicing and 3[prime] end processing
- Full text
- PDF (293 KB) - A 10 residue motif at the C-terminus of the RNA pol II CTD is required for transcription, splicing and 3[prime] end processing
- Supplementary information
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A common sequence motif determines the Cajal body-specific localization of box H/ACA scaRNAs FREE
The EMBO Journal (2003), 22, - 4283 - 4293, doi:10.1093/emboj/cdg394
- Abstract - A common sequence motif determines the Cajal body-specific localization of box H/ACA scaRNAs
- Full text
- PDF (402 KB) - A common sequence motif determines the Cajal body-specific localization of box H/ACA scaRNAs
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Localization of proteins bound to a replication origin of human DNA along the cell cycle FREE
The EMBO Journal (2003), 22, - 4294 - 4303, doi:10.1093/emboj/cdg404
- Abstract - Localization of proteins bound to a replication origin of human DNA along the cell cycle
- Full text
- PDF (380 KB) - Localization of proteins bound to a replication origin of human DNA along the cell cycle
- Supplementary information
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Elg1 forms an alternative RFC complex important for DNA replication and genome integrity FREE
The EMBO Journal (2003), 22, - 4304 - 4313, doi:10.1093/emboj/cdg406
- Abstract - Elg1 forms an alternative RFC complex important for DNA replication and genome integrity
- Full text
- PDF (353 KB) - Elg1 forms an alternative RFC complex important for DNA replication and genome integrity
- Supplementary information
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Nucleotide shuffling and ssDNA recognition in Oxytricha nova telomere end-binding protein complexes FREE
The EMBO Journal (2003), 22, - 4314 - 4324, doi:10.1093/emboj/cdg415
- Abstract - Nucleotide shuffling and ssDNA recognition in : Oxytricha nova: telomere end-binding protein complexes
- Full text
- PDF (491 KB) - Nucleotide shuffling and ssDNA recognition in : Oxytricha nova: telomere end-binding protein complexes
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DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1 FREE
The EMBO Journal (2003), 22, - 4325 - 4336, doi:10.1093/emboj/cdg391
- Abstract - DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1
- Full text
- PDF (404 KB) - DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1
- Supplementary information
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