Table of Contents
Volume 22, Number 11
01 June 2003
pp 2537-2872
Cover. 'Teichstein' (photographic collage, 70 
100 cm). Part of a series entitled 'Synthesen: MPI-CBG Dresden'. The Max-Planck-Institute for Molecular Cell Biology and Genetics (MPI-CBG) in Dresden, Germany, was constructed by the architects Heikkinen & Komonen and HENN Architekten Ingenieure. From the very beginning the architecture was developed in close collaboration with the scientists to create an inspiring working space to meet the new scientific ideas and concepts which gave rise to the foundation of the MPI-CBG. Ten collages resulted from a photographic analysis of the building, including 'Teichstein', in which the oval pond in the garden is transformed into a rectangular view. The works of the 'Synthesen' series provide a constructive discussion about the architecture of the MPI-CBG, and about building for science in general. Jan C.L.Massner is a PhD student in the group of Professor Jean Pieters in the department of biochemistry at the Biozentrum of the University of Basel, Switzerland.
New EMBO Members Review
Top of pageRegulation of neuronal survival and death by extracellular signals during development FREE
The EMBO Journal (2003), 22, - 2537 - 2545, doi:10.1093/emboj/cdg254
- Abstract - Regulation of neuronal survival and death by extracellular signals during development
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- PDF (116 KB) - Regulation of neuronal survival and death by extracellular signals during development
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Dendritic cell regulation of immune responses: a new role for interleukin 2 at the intersection of innate and adaptive immunity FREE
The EMBO Journal (2003), 22, - 2546 - 2551, doi:10.1093/emboj/cdg261
- Abstract - Dendritic cell regulation of immune responses: a new role for interleukin 2 at the intersection of innate and adaptive immunity
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- PDF (127 KB) - Dendritic cell regulation of immune responses: a new role for interleukin 2 at the intersection of innate and adaptive immunity
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NF-
B and virus infection: who controls whom
FREE The EMBO Journal (2003), 22, - 2552 - 2560, doi:10.1093/emboj/cdg267
- Abstract - NF-[kappa]B and virus infection: who controls whom
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- PDF (239 KB) - NF-[kappa]B and virus infection: who controls whom
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Articles
Top of pageInsights into ssDNA recognition by the OB fold from a structural and thermodynamic study of Sulfolobus SSB protein FREE
The EMBO Journal (2003), 22, - 2561 - 2570, doi:10.1093/emboj/cdg272
- Abstract - Insights into ssDNA recognition by the OB fold from a structural and thermodynamic study of : Sulfolobus: SSB protein
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- PDF (403 KB) - Insights into ssDNA recognition by the OB fold from a structural and thermodynamic study of : Sulfolobus: SSB protein
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Structural basis for SH3 domain-mediated high-affinity binding between Mona/Gads and SLP-76 FREE
The EMBO Journal (2003), 22, - 2571 - 2582, doi:10.1093/emboj/cdg258
- Abstract - Structural basis for SH3 domain-mediated high-affinity binding between Mona/Gads and SLP-76
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- PDF (557 KB) - Structural basis for SH3 domain-mediated high-affinity binding between Mona/Gads and SLP-76
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Structure of Rhodococcus erythropolis limonene-1,2-epoxide hydrolase reveals a novel active site FREE
The EMBO Journal (2003), 22, - 2583 - 2592, doi:10.1093/emboj/cdg275
- Abstract - Structure of : Rhodococcus erythropolis: limonene-1,2-epoxide hydrolase reveals a novel active site
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- PDF (345 KB) - Structure of : Rhodococcus erythropolis: limonene-1,2-epoxide hydrolase reveals a novel active site
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Crystal structure of tRNA(m1G37)methyltransferase: insights into tRNA recognition FREE
The EMBO Journal (2003), 22, - 2593 - 2603, doi:10.1093/emboj/cdg269
- Abstract - Crystal structure of tRNA(m: 1: G37)methyltransferase: insights into tRNA recognition
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- PDF (630 KB) - Crystal structure of tRNA(m: 1: G37)methyltransferase: insights into tRNA recognition
- Supplementary information
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Structures of immature flavivirus particles FREE
The EMBO Journal (2003), 22, - 2604 - 2613, doi:10.1093/emboj/cdg270
- Abstract - Structures of immature flavivirus particles
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- PDF (528 KB) - Structures of immature flavivirus particles
- Supplementary information
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A reducing system of the superoxide sensor SoxR in Escherichia coli FREE
The EMBO Journal (2003), 22, - 2614 - 2622, doi:10.1093/emboj/cdg252
- Abstract - A reducing system of the superoxide sensor SoxR in : Escherichia coli
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- PDF (282 KB) - A reducing system of the superoxide sensor SoxR in : Escherichia coli
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NADPH oxidase AtrbohD and AtrbohF genes function in ROS-dependent ABA signaling in Arabidopsis FREE
The EMBO Journal (2003), 22, - 2623 - 2633, doi:10.1093/emboj/cdg277
- Abstract - NADPH oxidase : AtrbohD: and : AtrbohF: genes function in ROS-dependent ABA signaling in : Arabidopsis
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- PDF (365 KB) - NADPH oxidase : AtrbohD: and : AtrbohF: genes function in ROS-dependent ABA signaling in : Arabidopsis
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Role of the CD47–SHPS-1 system in regulation of cell migration FREE
The EMBO Journal (2003), 22, - 2634 - 2644, doi:10.1093/emboj/cdg278
- Abstract - Role of the CD47-SHPS-1 system in regulation of cell migration
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- PDF (389 KB) - Role of the CD47-SHPS-1 system in regulation of cell migration
- Supplementary information
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Rabaptin-5
/rabaptin-4 serves as a linker between rab4 and 
1-adaptin in membrane recycling from endosomes
FREE The EMBO Journal (2003), 22, - 2645 - 2657, doi:10.1093/emboj/cdg257
- Abstract - Rabaptin-5[alpha]/rabaptin-4 serves as a linker between rab4 and [gamma]: 1: -adaptin in membrane recycling from endosomes
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- PDF (636 KB) - Rabaptin-5[alpha]/rabaptin-4 serves as a linker between rab4 and [gamma]: 1: -adaptin in membrane recycling from endosomes
- Supplementary information
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A cholesterol-regulated PP2A/HePTP complex with dual specificity ERK1/2 phosphatase activity FREE
The EMBO Journal (2003), 22, - 2658 - 2667, doi:10.1093/emboj/cdg255
- Abstract - A cholesterol-regulated PP2A/HePTP complex with dual specificity ERK1/2 phosphatase activity
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- PDF (297 KB) - A cholesterol-regulated PP2A/HePTP complex with dual specificity ERK1/2 phosphatase activity
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Haploinsufficiency-based large-scale forward genetic analysis of filamentous growth in the diploid human fungal pathogen C.albicans FREE
The EMBO Journal (2003), 22, - 2668 - 2678, doi:10.1093/emboj/cdg256
- Abstract - Haploinsufficiency-based large-scale forward genetic analysis of filamentous growth in the diploid human fungal pathogen : C.albicans
- Full text
- PDF (268 KB) - Haploinsufficiency-based large-scale forward genetic analysis of filamentous growth in the diploid human fungal pathogen : C.albicans
- Supplementary information
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TCGAP, a multidomain Rho GTPase-activating protein involved in insulin-stimulated glucose transport FREE
The EMBO Journal (2003), 22, - 2679 - 2691, doi:10.1093/emboj/cdg262
- Abstract - TCGAP, a multidomain Rho GTPase-activating protein involved in insulin-stimulated glucose transport
- Full text
- PDF (586 KB) - TCGAP, a multidomain Rho GTPase-activating protein involved in insulin-stimulated glucose transport
- Supplementary information
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Glycoprotein hormone receptors: determinants in leucine-rich repeats responsible for ligand specificity FREE
The EMBO Journal (2003), 22, - 2692 - 2703, doi:10.1093/emboj/cdg260
- Abstract - Glycoprotein hormone receptors: determinants in leucine-rich repeats responsible for ligand specificity
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- PDF (728 KB) - Glycoprotein hormone receptors: determinants in leucine-rich repeats responsible for ligand specificity
- Supplementary information
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Defective valvulogenesis in HB-EGF and TACE-null mice is associated with aberrant BMP signaling FREE
The EMBO Journal (2003), 22, - 2704 - 2716, doi:10.1093/emboj/cdg264
- Abstract - Defective valvulogenesis in HB-EGF and TACE-null mice is associated with aberrant BMP signaling
- Full text
- PDF (711 KB) - Defective valvulogenesis in HB-EGF and TACE-null mice is associated with aberrant BMP signaling
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Caspase 3 activation is essential for efficient influenza virus propagation FREE
The EMBO Journal (2003), 22, - 2717 - 2728, doi:10.1093/emboj/cdg279
- Abstract - Caspase 3 activation is essential for efficient influenza virus propagation
- Full text
- PDF (521 KB) - Caspase 3 activation is essential for efficient influenza virus propagation
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HBXIP functions as a cofactor of survivin in apoptosis suppression FREE
The EMBO Journal (2003), 22, - 2729 - 2740, doi:10.1093/emboj/cdg263
- Abstract - HBXIP functions as a cofactor of survivin in apoptosis suppression
- Full text
- PDF (514 KB) - HBXIP functions as a cofactor of survivin in apoptosis suppression
- Supplementary information
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The magnitude of hedgehog signaling activity defines skin tumor phenotype FREE
The EMBO Journal (2003), 22, - 2741 - 2751, doi:10.1093/emboj/cdg271
- Abstract - The magnitude of hedgehog signaling activity defines skin tumor phenotype
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- PDF (678 KB) - The magnitude of hedgehog signaling activity defines skin tumor phenotype
- Supplementary information
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The role of Ppe1/PP6 phosphatase for equal chromosome segregation in fission yeast kinetochore FREE
The EMBO Journal (2003), 22, - 2752 - 2763, doi:10.1093/emboj/cdg266
- Abstract - The role of Ppe1/PP6 phosphatase for equal chromosome segregation in fission yeast kinetochore
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- PDF (574 KB) - The role of Ppe1/PP6 phosphatase for equal chromosome segregation in fission yeast kinetochore
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Condensin but not cohesin SMC heterodimer induces DNA reannealing through protein–protein assembly FREE
The EMBO Journal (2003), 22, - 2764 - 2775, doi:10.1093/emboj/cdg247
- Abstract - Condensin but not cohesin SMC heterodimer induces DNA reannealing through protein-protein assembly
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- PDF (469 KB) - Condensin but not cohesin SMC heterodimer induces DNA reannealing through protein-protein assembly
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Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity FREE
The EMBO Journal (2003), 22, - 2776 - 2787, doi:10.1093/emboj/cdg248
- Abstract - Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity
- Full text
- PDF (649 KB) - Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity
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MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14 FREE
The EMBO Journal (2003), 22, - 2788 - 2797, doi:10.1093/emboj/cdg273
- Abstract - MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14
- Full text
- PDF (397 KB) - MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14
- Supplementary information
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Epigenetic consequences of AML1–ETO action at the human c-FMS locus FREE
The EMBO Journal (2003), 22, - 2798 - 2809, doi:10.1093/emboj/cdg250
- Abstract - Epigenetic consequences of AML1-ETO action at the human c-FMS locus
- Full text
- PDF (434 KB) - Epigenetic consequences of AML1-ETO action at the human c-FMS locus
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p53 represses RNA polymerase III transcription by targeting TBP and inhibiting promoter occupancy by TFIIIB FREE
The EMBO Journal (2003), 22, - 2810 - 2820, doi:10.1093/emboj/cdg265
- Abstract - p53 represses RNA polymerase III transcription by targeting TBP and inhibiting promoter occupancy by TFIIIB
- Full text
- PDF (302 KB) - p53 represses RNA polymerase III transcription by targeting TBP and inhibiting promoter occupancy by TFIIIB
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Recognition of GU-rich polyadenylation regulatory elements by human CstF-64 protein FREE
The EMBO Journal (2003), 22, - 2821 - 2830, doi:10.1093/emboj/cdg259
- Abstract - Recognition of GU-rich polyadenylation regulatory elements by human CstF-64 protein
- Full text
- PDF (334 KB) - Recognition of GU-rich polyadenylation regulatory elements by human CstF-64 protein
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Pti1p and Ref2p found in association with the mRNA 3' end formation complex direct snoRNA maturation FREE
The EMBO Journal (2003), 22, - 2831 - 2840, doi:10.1093/emboj/cdg253
- Abstract - Pti1p and Ref2p found in association with the mRNA 3[prime] end formation complex direct snoRNA maturation
- Full text
- PDF (292 KB) - Pti1p and Ref2p found in association with the mRNA 3[prime] end formation complex direct snoRNA maturation
- Supplementary information
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Coordinated nuclear export of 60S ribosomal subunits and NMD3 in vertebrates FREE
The EMBO Journal (2003), 22, - 2841 - 2851, doi:10.1093/emboj/cdg249
- Abstract - Coordinated nuclear export of 60S ribosomal subunits and NMD3 in vertebrates
- Full text
- PDF (366 KB) - Coordinated nuclear export of 60S ribosomal subunits and NMD3 in vertebrates
- Supplementary information
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The genome-linked protein VPg of the Norwalk virus binds eIF3, suggesting its role in translation initiation complex recruitment FREE
The EMBO Journal (2003), 22, - 2852 - 2859, doi:10.1093/emboj/cdg251
- Abstract - The genome-linked protein VPg of the Norwalk virus binds eIF3, suggesting its role in translation initiation complex recruitment
- Full text
- PDF (160 KB) - The genome-linked protein VPg of the Norwalk virus binds eIF3, suggesting its role in translation initiation complex recruitment
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A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein FREE
The EMBO Journal (2003), 22, - 2860 - 2871, doi:10.1093/emboj/cdg274
- Abstract - A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein
- Full text
- PDF (452 KB) - A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein
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Erratum
Top of pageAn H-bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors FREE
The EMBO Journal (2003), 22, - 2872, doi:10.1093/emboj/cdg309
