Table of Contents

Volume 21, Number 3
01 February 2002
pp 195-481
Cover. A fanciful depiction of Archaeoglobus fulgidus reverse gyrase molecules floating around a DNA double helix. Reverse gyrase is unique to hyperthermophiles, where its positive supercoiling activity is believed to protect DNA from heat denaturation. Archaeoglobus fulgidus, like many other hyperthermophiles, typically lives in deep sea vents at temperatures above 70°C. The image was created using MolScript and POV-Ray. For further details see Rodríguez and Stock, pages 418--426.
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Top of pageThe connection between transcription and genomic instability FREE
The EMBO Journal (2002), 21, - 195 - 201, doi:10.1093/emboj/21.3.195
- Abstract - The connection between transcription and genomic instability
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Articles
Top of pagePost-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration FREE
The EMBO Journal (2002), 21, - 202 - 210, doi:10.1093/emboj/21.3.202
- Abstract - Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration
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Disabled-2 is transcriptionally regulated by ICSBP and augments macrophage spreading and adhesion FREE
The EMBO Journal (2002), 21, - 211 - 220, doi:10.1093/emboj/21.3.211
- Abstract - Disabled-2 is transcriptionally regulated by ICSBP and augments macrophage spreading and adhesion
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The ATP synthase is involved in generating mitochondrial cristae morphology FREE
The EMBO Journal (2002), 21, - 221 - 230, doi:10.1093/emboj/21.3.221
- Abstract - The ATP synthase is involved in generating mitochondrial cristae morphology
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The crystal structure of the zymogen catalytic domain of complement protease C1r reveals that a disruptive mechanical stress is required to trigger activation of the C1 complex FREE
The EMBO Journal (2002), 21, - 231 - 239, doi:10.1093/emboj/21.3.231
- Abstract - The crystal structure of the zymogen catalytic domain of complement protease C1r reveals that a disruptive mechanical stress is required to trigger activation of the C1 complex
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The dynamin A ring complex: molecular organization and nucleotide-dependent conformational changes FREE
The EMBO Journal (2002), 21, - 240 - 250, doi:10.1093/emboj/21.3.240
- Abstract - The dynamin A ring complex: molecular organization and nucleotide-dependent conformational changes
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Contrasting requirements for ubiquitylation during Fc receptor-mediated endocytosis and phagocytosis FREE
The EMBO Journal (2002), 21, - 251 - 258, doi:10.1093/emboj/21.3.251
- Abstract - Contrasting requirements for ubiquitylation during Fc receptor-mediated endocytosis and phagocytosis
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The Vtc proteins in vacuole fusion: coupling NSF activity to V0trans-complex formation FREE
The EMBO Journal (2002), 21, - 259 - 269, doi:10.1093/emboj/21.3.259
- Abstract - The Vtc proteins in vacuole fusion: coupling NSF activity to V: 0: : trans: -complex formation
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Synaptotagmins form a hierarchy of exocytotic Ca2+ sensors with distinct Ca2+ affinities FREE
The EMBO Journal (2002), 21, - 270 - 280, doi:10.1093/emboj/21.3.270
- Abstract - Synaptotagmins form a hierarchy of exocytotic Ca: 2+: sensors with distinct Ca: 2+: affinities
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- PDF (314 KB) - Synaptotagmins form a hierarchy of exocytotic Ca: 2+: sensors with distinct Ca: 2+: affinities
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Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility FREE
The EMBO Journal (2002), 21, - 281 - 293, doi:10.1093/emboj/21.3.281
- Abstract - Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility
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Integrity of intracellular domain of Notch ligand is indispensable for cleavage required for release of the Notch2 intracellular domain FREE
The EMBO Journal (2002), 21, - 294 - 302, doi:10.1093/emboj/21.3.294
- Abstract - Integrity of intracellular domain of Notch ligand is indispensable for cleavage required for release of the Notch2 intracellular domain
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A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling FREE
The EMBO Journal (2002), 21, - 303 - 313, doi:10.1093/emboj/21.3.303
- Abstract - A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling
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- PDF (361 KB) - A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling
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A 'three-pronged' binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome FREE
The EMBO Journal (2002), 21, - 314 - 323, doi:10.1093/emboj/21.3.314
- Abstract - A 'three-pronged' binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome
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- PDF (293 KB) - A 'three-pronged' binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome
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Cyclin-dependent kinase 5 prevents neuronal apoptosis by negative regulation of c-Jun N-terminal kinase 3 FREE
The EMBO Journal (2002), 21, - 324 - 333, doi:10.1093/emboj/21.3.324
- Abstract - Cyclin-dependent kinase 5 prevents neuronal apoptosis by negative regulation of c-Jun N-terminal kinase 3
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- PDF (372 KB) - Cyclin-dependent kinase 5 prevents neuronal apoptosis by negative regulation of c-Jun N-terminal kinase 3
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NF1/X represses PDGF A-chain transcription by interacting with Sp1 and antagonizing Sp1 occupancy of the promoter FREE
The EMBO Journal (2002), 21, - 334 - 343, doi:10.1093/emboj/21.3.334
- Abstract - NF1/X represses PDGF A-chain transcription by interacting with Sp1 and antagonizing Sp1 occupancy of the promoter
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- PDF (263 KB) - NF1/X represses PDGF A-chain transcription by interacting with Sp1 and antagonizing Sp1 occupancy of the promoter
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Constitutive and IFN-
-induced nuclear import of STAT1 proceed through independent pathways
FREE The EMBO Journal (2002), 21, - 344 - 354, doi:10.1093/emboj/21.3.344
- Abstract - Constitutive and IFN-[gamma]-induced nuclear import of STAT1 proceed through independent pathways
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- PDF (480 KB) - Constitutive and IFN-[gamma]-induced nuclear import of STAT1 proceed through independent pathways
- Supplementary information
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Identification of a ubiquitin–protein ligase subunit within the CCR4–NOT transcription repressor complex FREE
The EMBO Journal (2002), 21, - 355 - 364, doi:10.1093/emboj/21.3.355
- Abstract - Identification of a ubiquitin-protein ligase subunit within the CCR4-NOT transcription repressor complex
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- PDF (340 KB) - Identification of a ubiquitin-protein ligase subunit within the CCR4-NOT transcription repressor complex
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Krox20 and kreisler co-operate in the transcriptional control of segmental expression of Hoxb3 in the developing hindbrain FREE
The EMBO Journal (2002), 21, - 365 - 376, doi:10.1093/emboj/21.3.365
- Abstract - Krox20 and kreisler co-operate in the transcriptional control of segmental expression of : Hoxb3: in the developing hindbrain
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- PDF (434 KB) - Krox20 and kreisler co-operate in the transcriptional control of segmental expression of : Hoxb3: in the developing hindbrain
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Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains FREE
The EMBO Journal (2002), 21, - 377 - 386, doi:10.1093/emboj/21.3.377
- Abstract - Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains
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- PDF (319 KB) - Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains
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Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins FREE
The EMBO Journal (2002), 21, - 387 - 397, doi:10.1093/emboj/21.3.387
- Abstract - Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins
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A viral protein inhibits the long range signaling activity of the gene silencing signal FREE
The EMBO Journal (2002), 21, - 398 - 407, doi:10.1093/emboj/21.3.398
- Abstract - A viral protein inhibits the long range signaling activity of the gene silencing signal
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Transplantation of target site specificity by swapping the endonuclease domains of two LINEs FREE
The EMBO Journal (2002), 21, - 408 - 417, doi:10.1093/emboj/21.3.408
- Abstract - Transplantation of target site specificity by swapping the endonuclease domains of two LINEs
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- PDF (316 KB) - Transplantation of target site specificity by swapping the endonuclease domains of two LINEs
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Crystal structure of reverse gyrase: insights into the positive supercoiling of DNA FREE
The EMBO Journal (2002), 21, - 418 - 426, doi:10.1093/emboj/21.3.418
- Abstract - Crystal structure of reverse gyrase: insights into the positive supercoiling of DNA
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- PDF (483 KB) - Crystal structure of reverse gyrase: insights into the positive supercoiling of DNA
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Crystal structures of a template-independent DNA polymerase: murine terminal deoxynucleotidyltransferase FREE
The EMBO Journal (2002), 21, - 427 - 439, doi:10.1093/emboj/21.3.427
- Abstract - Crystal structures of a template-independent DNA polymerase: murine terminal deoxynucleotidyltransferase
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- PDF (792 KB) - Crystal structures of a template-independent DNA polymerase: murine terminal deoxynucleotidyltransferase
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Transvection effects involving DNA methylation during meiosis in the mouse FREE
The EMBO Journal (2002), 21, - 440 - 450, doi:10.1093/emboj/21.3.440
- Abstract - Transvection effects involving DNA methylation during meiosis in the mouse
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- PDF (330 KB) - Transvection effects involving DNA methylation during meiosis in the mouse
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The DEXD/H-box RNA helicase RHII/Gu is a co-factor for c-Jun-activated transcription FREE
The EMBO Journal (2002), 21, - 451 - 460, doi:10.1093/emboj/21.3.451
- Abstract - The DEXD/H-box RNA helicase RHII/Gu is a co-factor for c-Jun-activated transcription
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- PDF (298 KB) - The DEXD/H-box RNA helicase RHII/Gu is a co-factor for c-Jun-activated transcription
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Endogenous viral sequences and their potential contribution to heritable virus resistance in plants FREE
The EMBO Journal (2002), 21, - 461 - 469, doi:10.1093/emboj/21.3.461
- Abstract - Endogenous viral sequences and their potential contribution to heritable virus resistance in plants
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- PDF (236 KB) - Endogenous viral sequences and their potential contribution to heritable virus resistance in plants
Published online: 01 February 2002
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A cyclophilin functions in pre-mRNA splicing FREE
The EMBO Journal (2002), 21, - 470 - 480, doi:10.1093/emboj/21.3.470
- Abstract - A cyclophilin functions in pre-mRNA splicing
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- PDF (324 KB) - A cyclophilin functions in pre-mRNA splicing
- Supplementary information
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Erratum
Top of pageOrigin pairing ('handcuffing') as a mode of negative control of P1 plasmid copy number FREE
The EMBO Journal (2002), 21, - 481, doi:10.1093/emboj/21.3.481



