Table of Contents
Volume 21, Number 11
03 June 2002
pp 2509-2841
Cover. Central American red-eyed tree frog. 'I was in the Barra del Colorado Wildlife Refuge in Costa Rica when I noticed this frog on a plant near the hut where we were staying. The rain had just cleared'. Dr Graeme Guy is a Principal Investigator of the Signal Transduction Laboratory at the Institute of Molecular and Cell Biology in Singapore. He is a keen amateur nature photographer; this image (or related ones) has won 12 medals in international photographic salons. The image was taken with a Canon EOS1N, 180mm macro lens, 1/250th, f 22, with three flash heads for illumination.
Articles
Top of pageStructure of malonamidase E2 reveals a novel Ser-cisSer-Lys catalytic triad in a new serine hydrolase fold that is prevalent in nature FREE
The EMBO Journal (2002), 21, - 2509 - 2516, doi:10.1093/emboj/21.11.2509
- Abstract - Structure of malonamidase E2 reveals a novel Ser-: cis: Ser-Lys catalytic triad in a new serine hydrolase fold that is prevalent in nature
- Full text
- PDF (456 KB) - Structure of malonamidase E2 reveals a novel Ser-: cis: Ser-Lys catalytic triad in a new serine hydrolase fold that is prevalent in nature
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Crystal structure of the motor domain of a class-I myosin FREE
The EMBO Journal (2002), 21, - 2517 - 2525, doi:10.1093/emboj/21.11.2517
- Abstract - Crystal structure of the motor domain of a class-I myosin
- Full text
- PDF (305 KB) - Crystal structure of the motor domain of a class-I myosin
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The Toxoplasma gondii protein MIC3 requires pro-peptide cleavage and dimerization to function as adhesin FREE
The EMBO Journal (2002), 21, - 2526 - 2536, doi:10.1093/emboj/21.11.2526
- Abstract - The : Toxoplasma gondii: protein MIC3 requires pro-peptide cleavage and dimerization to function as adhesin
- Full text
- PDF (451 KB) - The : Toxoplasma gondii: protein MIC3 requires pro-peptide cleavage and dimerization to function as adhesin
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Fast dissociation kinetics between individual E-cadherin fragments revealed by flow chamber analysis FREE
The EMBO Journal (2002), 21, - 2537 - 2546, doi:10.1093/emboj/21.11.2537
- Abstract - Fast dissociation kinetics between individual E-cadherin fragments revealed by flow chamber analysis
- Full text
- PDF (208 KB) - Fast dissociation kinetics between individual E-cadherin fragments revealed by flow chamber analysis
- Supplementary information
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Ca2+ sensor S100
-modulated sites of membrane guanylate cyclase in thephotoreceptor-bipolar synapse
FREE The EMBO Journal (2002), 21, - 2547 - 2556, doi:10.1093/emboj/21.11.2547
- Abstract - Ca: 2+: sensor S100[beta]-modulated sites of membrane guanylate cyclase in thephotoreceptor-bipolar synapse
- Full text
- PDF (284 KB) - Ca: 2+: sensor S100[beta]-modulated sites of membrane guanylate cyclase in thephotoreceptor-bipolar synapse
- Supplementary information
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A tubular EHD1-containing compartment involved in the recycling of major histocompatibility complex class I molecules to the plasma membrane FREE
The EMBO Journal (2002), 21, - 2557 - 2567, doi:10.1093/emboj/21.11.2557
- Abstract - A tubular EHD1-containing compartment involved in the recycling of major histocompatibility complex class I molecules to the plasma membrane
- Full text
- PDF (545 KB) - A tubular EHD1-containing compartment involved in the recycling of major histocompatibility complex class I molecules to the plasma membrane
- Supplementary information
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The Toll and Imd pathways are the major regulators of the immune response in Drosophila FREE
The EMBO Journal (2002), 21, - 2568 - 2579, doi:10.1093/emboj/21.11.2568
- Abstract - The Toll and Imd pathways are the major regulators of the immune response in : Drosophila
- Full text
- PDF (500 KB) - The Toll and Imd pathways are the major regulators of the immune response in : Drosophila
- Supplementary information
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Overexpression of Smad7 results in severe pathological alterations in multiple epithelial tissues FREE
The EMBO Journal (2002), 21, - 2580 - 2590, doi:10.1093/emboj/21.11.2580
- Abstract - Overexpression of Smad7 results in severe pathological alterations in multiple epithelial tissues
- Full text
- PDF (558 KB) - Overexpression of Smad7 results in severe pathological alterations in multiple epithelial tissues
- Supplementary information
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Brain abnormalities, defective meiotic chromosome synapsis and female subfertility in HSF2 null mice FREE
The EMBO Journal (2002), 21, - 2591 - 2601, doi:10.1093/emboj/21.11.2591
- Abstract - Brain abnormalities, defective meiotic chromosome synapsis and female subfertility in HSF2 null mice
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- PDF (473 KB) - Brain abnormalities, defective meiotic chromosome synapsis and female subfertility in HSF2 null mice
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Characterization of an anti-apoptotic glycoprotein encoded by Kaposi's sarcoma-associated herpesvirus which resembles a spliced variant of human survivin FREE
The EMBO Journal (2002), 21, - 2602 - 2615, doi:10.1093/emboj/21.11.2602
- Abstract - Characterization of an anti-apoptotic glycoprotein encoded by Kaposi's sarcoma-associated herpesvirus which resembles a spliced variant of human survivin
- Full text
- PDF (504 KB) - Characterization of an anti-apoptotic glycoprotein encoded by Kaposi's sarcoma-associated herpesvirus which resembles a spliced variant of human survivin
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The preprotein conducting channel at the inner envelope membrane of plastids FREE
The EMBO Journal (2002), 21, - 2616 - 2625, doi:10.1093/emboj/21.11.2616
- Abstract - The preprotein conducting channel at the inner envelope membrane of plastids
- Full text
- PDF (323 KB) - The preprotein conducting channel at the inner envelope membrane of plastids
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The Hsp70 peptide-binding domain determines the interaction of the ATPase domain with Tim44 in mitochondria FREE
The EMBO Journal (2002), 21, - 2626 - 2635, doi:10.1093/emboj/21.11.2626
- Abstract - The Hsp70 peptide-binding domain determines the interaction of the ATPase domain with Tim44 in mitochondria
- Full text
- PDF (319 KB) - The Hsp70 peptide-binding domain determines the interaction of the ATPase domain with Tim44 in mitochondria
- Supplementary information
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Properties of the hybrid form of the 26S proteasome containing both 19S and PA28 complexes FREE
The EMBO Journal (2002), 21, - 2636 - 2645, doi:10.1093/emboj/21.11.2636
- Abstract - Properties of the hybrid form of the 26S proteasome containing both 19S and PA28 complexes
- Full text
- PDF (360 KB) - Properties of the hybrid form of the 26S proteasome containing both 19S and PA28 complexes
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Paradoxical redox properties of DsbB and DsbA in the protein disulfide-introducing reaction cascade FREE
The EMBO Journal (2002), 21, - 2646 - 2654, doi:10.1093/emboj/21.11.2646
- Abstract - Paradoxical redox properties of DsbB and DsbA in the protein disulfide-introducing reaction cascade
- Full text
- PDF (234 KB) - Paradoxical redox properties of DsbB and DsbA in the protein disulfide-introducing reaction cascade
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The oxidoreductase ERp57 efficiently reduces partially folded in preference to fully folded MHC class I molecules FREE
The EMBO Journal (2002), 21, - 2655 - 2663, doi:10.1093/emboj/21.11.2655
- Abstract - The oxidoreductase ERp57 efficiently reduces partially folded in preference to fully folded MHC class I molecules
- Full text
- PDF (239 KB) - The oxidoreductase ERp57 efficiently reduces partially folded in preference to fully folded MHC class I molecules
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The permeability barrier of nuclear pore complexes appears to operate via hydrophobic exclusion FREE
The EMBO Journal (2002), 21, - 2664 - 2671, doi:10.1093/emboj/21.11.2664
- Abstract - The permeability barrier of nuclear pore complexes appears to operate via hydrophobic exclusion
- Full text
- PDF (276 KB) - The permeability barrier of nuclear pore complexes appears to operate via hydrophobic exclusion
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Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression FREE
The EMBO Journal (2002), 21, - 2672 - 2681, doi:10.1093/emboj/21.11.2672
- Abstract - Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression
- Full text
- PDF (420 KB) - Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression
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The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase FREE
The EMBO Journal (2002), 21, - 2682 - 2691, doi:10.1093/emboj/21.11.2682
- Abstract - The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase
- Full text
- PDF (300 KB) - The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase
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LOS2, a genetic locus required for cold-responsive gene transcription encodes a bi-functional enolase FREE
The EMBO Journal (2002), 21, - 2692 - 2702, doi:10.1093/emboj/21.11.2692
- Abstract - LOS2: , a genetic locus required for cold-responsive gene transcription encodes a bi-functional enolase
- Full text
- PDF (512 KB) - LOS2: , a genetic locus required for cold-responsive gene transcription encodes a bi-functional enolase
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Microphthalmia-associated transcription factor interacts with LEF-1, a mediator of Wnt signaling FREE
The EMBO Journal (2002), 21, - 2703 - 2714, doi:10.1093/emboj/21.11.2703
- Abstract - Microphthalmia-associated transcription factor interacts with LEF-1, a mediator of Wnt signaling
- Full text
- PDF (532 KB) - Microphthalmia-associated transcription factor interacts with LEF-1, a mediator of Wnt signaling
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Transcriptional synergy between Tat and PCAF is dependent on the binding of acetylated Tat to the PCAF bromodomain FREE
The EMBO Journal (2002), 21, - 2715 - 2723, doi:10.1093/emboj/21.11.2715
- Abstract - Transcriptional synergy between Tat and PCAF is dependent on the binding of acetylated Tat to the PCAF bromodomain
- Full text
- PDF (231 KB) - Transcriptional synergy between Tat and PCAF is dependent on the binding of acetylated Tat to the PCAF bromodomain
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p110, a novel human U6 snRNP protein and U4/U6 snRNP recycling factor FREE
The EMBO Journal (2002), 21, - 2724 - 2735, doi:10.1093/emboj/21.11.2724
- Abstract - p110, a novel human U6 snRNP protein and U4/U6 snRNP recycling factor
- Full text
- PDF (615 KB) - p110, a novel human U6 snRNP protein and U4/U6 snRNP recycling factor
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Mammalian and yeast U3 snoRNPs are matured in specific and related nuclear compartments FREE
The EMBO Journal (2002), 21, - 2736 - 2745, doi:10.1093/emboj/21.11.2736
- Abstract - Mammalian and yeast U3 snoRNPs are matured in specific and related nuclear compartments
- Full text
- PDF (472 KB) - Mammalian and yeast U3 snoRNPs are matured in specific and related nuclear compartments
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Cajal body-specific small nuclear RNAs: a novel class of 2'-O-methylation and pseudouridylation guide RNAs FREE
The EMBO Journal (2002), 21, - 2746 - 2756, doi:10.1093/emboj/21.11.2746
- Abstract - Cajal body-specific small nuclear RNAs: a novel class of 2[prime]-: O: -methylation and pseudouridylation guide RNAs
- Full text
- PDF (325 KB) - Cajal body-specific small nuclear RNAs: a novel class of 2[prime]-: O: -methylation and pseudouridylation guide RNAs
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An RNA cap (nucleoside-2'-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization FREE
The EMBO Journal (2002), 21, - 2757 - 2768, doi:10.1093/emboj/21.11.2757
- Abstract - An RNA cap (nucleoside-2[prime]-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization
- Full text
- PDF (511 KB) - An RNA cap (nucleoside-2[prime]-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization
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Assigning a function to a conserved group of proteins: the tRNA 3'-processing enzymes FREE
The EMBO Journal (2002), 21, - 2769 - 2777, doi:10.1093/emboj/21.11.2769
- Abstract - Assigning a function to a conserved group of proteins: the tRNA 3[prime]-processing enzymes
- Full text
- PDF (295 KB) - Assigning a function to a conserved group of proteins: the tRNA 3[prime]-processing enzymes
- Supplementary information
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Structural origins of amino acid selection without editing by cysteinyl-tRNA synthetase FREE
The EMBO Journal (2002), 21, - 2778 - 2787, doi:10.1093/emboj/21.11.2778
- Abstract - Structural origins of amino acid selection without editing by cysteinyl-tRNA synthetase
- Full text
- PDF (656 KB) - Structural origins of amino acid selection without editing by cysteinyl-tRNA synthetase
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The DEAD box protein Dhh1 stimulates the decapping enzyme Dcp1 FREE
The EMBO Journal (2002), 21, - 2788 - 2797, doi:10.1093/emboj/21.11.2788
- Abstract - The DEAD box protein Dhh1 stimulates the decapping enzyme Dcp1
- Full text
- PDF (255 KB) - The DEAD box protein Dhh1 stimulates the decapping enzyme Dcp1
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A novel regulatory element determines the timing of Mos mRNA translation during Xenopus oocyte maturation FREE
The EMBO Journal (2002), 21, - 2798 - 2806, doi:10.1093/emboj/21.11.2798
- Abstract - A novel regulatory element determines the timing of Mos mRNA translation during : Xenopus: oocyte maturation
- Full text
- PDF (246 KB) - A novel regulatory element determines the timing of Mos mRNA translation during : Xenopus: oocyte maturation
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The meiotic recombination checkpoint is regulated by checkpoint rad+ genes in fission yeast FREE
The EMBO Journal (2002), 21, - 2807 - 2818, doi:10.1093/emboj/21.11.2807
- Abstract - The meiotic recombination checkpoint is regulated by checkpoint : rad: +: genes in fission yeast
- Full text
- PDF (534 KB) - The meiotic recombination checkpoint is regulated by checkpoint : rad: +: genes in fission yeast
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Telomere length deregulation and enhanced sensitivity to genotoxic stress in Arabidopsis mutants deficient in Ku70 FREE
The EMBO Journal (2002), 21, - 2819 - 2826, doi:10.1093/emboj/21.11.2819
- Abstract - Telomere length deregulation and enhanced sensitivity to genotoxic stress in : Arabidopsis: mutants deficient in Ku70
- Full text
- PDF (215 KB) - Telomere length deregulation and enhanced sensitivity to genotoxic stress in : Arabidopsis: mutants deficient in Ku70
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Involvement of human polynucleotide kinase in double-strand break repair by non-homologous end joining FREE
The EMBO Journal (2002), 21, - 2827 - 2832, doi:10.1093/emboj/21.11.2827
- Abstract - Involvement of human polynucleotide kinase in double-strand break repair by non-homologous end joining
- Full text
- PDF (215 KB) - Involvement of human polynucleotide kinase in double-strand break repair by non-homologous end joining
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Endogenous DNA abasic sites cause cell death in the absence of Apn1, Apn2 and Rad1/Rad10 in Saccharomyces cerevisiae FREE
The EMBO Journal (2002), 21, - 2833 - 2841, doi:10.1093/emboj/21.11.2833
- Abstract - Endogenous DNA abasic sites cause cell death in the absence of Apn1, Apn2 and Rad1/Rad10 in : Saccharomyces cerevisiae
- Full text
- PDF (292 KB) - Endogenous DNA abasic sites cause cell death in the absence of Apn1, Apn2 and Rad1/Rad10 in : Saccharomyces cerevisiae
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