Table of Contents

Volume 20, Number 9
01 May 2001

pp 2111-2347

Cover. Tree (2000), original oil pastel (33 24 cm) by Mona Nemani. The artist is a research scientist at the Fondation Jean Dausset-CEPH, Paris, France, and works on the cloning and characterization of new genes involved in apoptosis and tumour suppression, and the genetics of ageing.

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  • Oligopeptide repeats in the yeast protein Sup35p stabilize intermolecular prion interactions FREE

    Steven N. Parham, Catarina G. Resende and Mick F. Tuite

    The EMBO Journal (2001), 20, - 2111 - 2119, doi:10.1093/emboj/20.9.2111

    • Abstract - Oligopeptide repeats in the yeast protein Sup35p stabilize intermolecular prion interactions
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  • Glycoprotein VI but not 21 integrin is essential for platelet interaction with collagen FREE

    Bernhard Nieswandt, Cord Brakebusch, Wolfgang Bergmeier, Valerie Schulte, Daniel Bouvard, Rabée Mokhtari-Nejad, Theo Lindhout, Johan W.M. Heemskerk, Hubert Zirngibl and Reinhard Fässler

    The EMBO Journal (2001), 20, - 2120 - 2130, doi:10.1093/emboj/20.9.2120

    • Abstract - Glycoprotein VI but not [alpha]2[beta]1 integrin is essential for platelet interaction with collagen
    • Full text
    • PDF (475 KB) - Glycoprotein VI but not [alpha]2[beta]1 integrin is essential for platelet interaction with collagen

  • Cooperation between actin-binding proteins of invasive Salmonella: SipA potentiates SipC nucleation and bundling of actin FREE

    Emma J. McGhie, Richard D. Hayward and Vassilis Koronakis

    The EMBO Journal (2001), 20, - 2131 - 2139, doi:10.1093/emboj/20.9.2131

    • Abstract - Cooperation between actin-binding proteins of invasive : Salmonella: : SipA potentiates SipC nucleation and bundling of actin
    • Full text
    • PDF (351 KB) - Cooperation between actin-binding proteins of invasive : Salmonella: : SipA potentiates SipC nucleation and bundling of actin

  • The tripartite motif family identifies cell compartments FREE

    Alexandre Reymond, Germana Meroni, Anna Fantozzi, Giuseppe Merla, Stefano Cairo, Lucilla Luzi, Daniela Riganelli, Elena Zanaria, Silvia Messali, Silvia Cainarca, Alessandro Guffanti, Saverio Minucci, Pier Giuseppe Pelicci and Andrea Ballabio

    The EMBO Journal (2001), 20, - 2140 - 2151, doi:10.1093/emboj/20.9.2140

    • Abstract - The tripartite motif family identifies cell compartments
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    • PDF (788 KB) - The tripartite motif family identifies cell compartments

  • Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA_B receptor function FREE

    Thierry Galvez, Béatrice Duthey, Julie Kniazeff, Jaroslav Blahos, Giorgio Rovelli, Bernhard Bettler, Laurent Prézeau and Jean-Philippe Pin

    The EMBO Journal (2001), 20, - 2152 - 2159, doi:10.1093/emboj/20.9.2152

    • Abstract - Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA: B: receptor function
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    • PDF (269 KB) - Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA: B: receptor function

  • Modulation of integrin signal transduction by ILKAP, a protein phosphatase 2C associating with the integrin-linked kinase, ILK1 FREE

    Chungyee Leung-Hagesteijn, Ahalya Mahendra, Izabela Naruszewicz and Gregory E. Hannigan

    The EMBO Journal (2001), 20, - 2160 - 2170, doi:10.1093/emboj/20.9.2160

    • Abstract - Modulation of integrin signal transduction by ILKAP, a protein phosphatase 2C associating with the integrin-linked kinase, ILK1
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    • PDF (519 KB) - Modulation of integrin signal transduction by ILKAP, a protein phosphatase 2C associating with the integrin-linked kinase, ILK1

  • cdc42 regulates the exit of apical and basolateral proteins from the trans-Golgi network FREE

    Anne Müsch, David Cohen, Geri Kreitzer and Enrique Rodriguez-Boulan

    The EMBO Journal (2001), 20, - 2171 - 2179, doi:10.1093/emboj/20.9.2171

    • Abstract - cdc42 regulates the exit of apical and basolateral proteins from the : trans: -Golgi network
    • Full text
    • PDF (421 KB) - cdc42 regulates the exit of apical and basolateral proteins from the : trans: -Golgi network
    • Supplementary information

  • The sortilin cytoplasmic tail conveys Golgi–endosome transport and binds the VHS domain of the GGA2 sorting protein FREE

    Morten S. Nielsen, Peder Madsen, Erik I. Christensen, Anders Nykjær, Jørgen Gliemann, Dagmar Kasper, Regina Pohlmann and Claus M. Petersen

    The EMBO Journal (2001), 20, - 2180 - 2190, doi:10.1093/emboj/20.9.2180

    • Abstract - The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein
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    • PDF (439 KB) - The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein

  • PACS-1 binding to adaptors is required for acidic cluster motif-mediated protein traffic FREE

    Colin M. Crump, Yang Xiang, Laurel Thomas, Feng Gu, Carol Austin, Sharon A. Tooze and Gary Thomas

    The EMBO Journal (2001), 20, - 2191 - 2201, doi:10.1093/emboj/20.9.2191

    • Abstract - PACS-1 binding to adaptors is required for acidic cluster motif-mediated protein traffic
    • Full text
    • PDF (455 KB) - PACS-1 binding to adaptors is required for acidic cluster motif-mediated protein traffic

  • SNAREs are concentrated in cholesterol-dependent clusters that define docking and fusion sites for exocytosis FREE

    Thorsten Lang, Dieter Bruns, Dirk Wenzel, Dietmar Riedel, Phillip Holroyd, Christoph Thiele and Reinhard Jahn

    The EMBO Journal (2001), 20, - 2202 - 2213, doi:10.1093/emboj/20.9.2202

    • Abstract - SNAREs are concentrated in cholesterol-dependent clusters that define docking and fusion sites for exocytosis
    • Full text
    • PDF (458 KB) - SNAREs are concentrated in cholesterol-dependent clusters that define docking and fusion sites for exocytosis

  • Patched1 interacts with cyclin B1 to regulate cell cycle progression FREE

    Elizabeth A. Barnes, Monica Kong, Vincent Ollendorff and Daniel J Donoghue

    The EMBO Journal (2001), 20, - 2214 - 2223, doi:10.1093/emboj/20.9.2214

    • Abstract - Patched1 interacts with cyclin B1 to regulate cell cycle progression
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    • PDF (367 KB) - Patched1 interacts with cyclin B1 to regulate cell cycle progression

  • Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci FREE

    Michael D. Litt, Melanie Simpson, Félix Recillas-Targa, Marie-Noëlle Prioleau and Gary Felsenfeld

    The EMBO Journal (2001), 20, - 2224 - 2235, doi:10.1093/emboj/20.9.2224

    • Abstract - Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci
    • Full text
    • PDF (614 KB) - Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci

  • Association and spreading of the Drosophila dosage compensation complex from a discrete roX1 chromatin entry site FREE

    Y. Kageyama, G. Mengus, G. Gilfillan, H. G. Kennedy, C. Stuckenholz, R. L. Kelley, P. B. Becker and M. I. Kuroda

    The EMBO Journal (2001), 20, - 2236 - 2245, doi:10.1093/emboj/20.9.2236

    • Abstract - Association and spreading of the : Drosophila: dosage compensation complex from a discrete : roX1: chromatin entry site
    • Full text
    • PDF (335 KB) - Association and spreading of the : Drosophila: dosage compensation complex from a discrete : roX1: chromatin entry site

  • Local action of long-range repressors in the Drosophila embryo FREE

    Yutaka Nibu, Hailan Zhang and Michael Levine

    The EMBO Journal (2001), 20, - 2246 - 2253, doi:10.1093/emboj/20.9.2246

    • Abstract - Local action of long-range repressors in the : Drosophila: embryo
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    • PDF (249 KB) - Local action of long-range repressors in the : Drosophila: embryo

  • TGF--induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation FREE

    Tamara Alliston, Lisa Choy, Patricia Ducy, Gérard Karsenty and Rik Derynck

    The EMBO Journal (2001), 20, - 2254 - 2272, doi:10.1093/emboj/20.9.2254

    • Abstract - TGF-[beta]-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation
    • Full text
    • PDF (667 KB) - TGF-[beta]-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation

  • TRIP-Br: a novel family of PHD zinc finger- and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1 FREE

    Stephen I-Hong Hsu, Christopher Maolin Yang, Khe Guan Sim, Dirk M. Hentschel, Eileen O'Leary and Joseph V. Bonventre

    The EMBO Journal (2001), 20, - 2273 - 2285, doi:10.1093/emboj/20.9.2273

    • Abstract - TRIP-Br: a novel family of PHD zinc finger- and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1
    • Full text
    • PDF (703 KB) - TRIP-Br: a novel family of PHD zinc finger- and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1

  • Interleukin 3-dependent activation of DREAM is involved in transcriptional silencing of the apoptotic hrk gene in hematopoietic progenitor cells FREE

    Cristina Sanz, Britt Mellstrom, Wolfgang A. Link, Jose Ramon Naranjo and Jose Luis Fernandez-Luna

    The EMBO Journal (2001), 20, - 2286 - 2292, doi:10.1093/emboj/20.9.2286

    • Abstract - Interleukin 3-dependent activation of DREAM is involved in transcriptional silencing of the apoptotic : hrk: gene in hematopoietic progenitor cells
    • Full text
    • PDF (218 KB) - Interleukin 3-dependent activation of DREAM is involved in transcriptional silencing of the apoptotic : hrk: gene in hematopoietic progenitor cells

  • RNA binding in an Sm core domain: X-ray structure and functional analysis of an archaeal Sm protein complex FREE

    Imre Törö, Stéphane Thore, Claudine Mayer, Jérôme Basquin, Bertrand Séraphin and Dietrich Suck

    The EMBO Journal (2001), 20, - 2293 - 2303, doi:10.1093/emboj/20.9.2293

    • Abstract - RNA binding in an Sm core domain: X-ray structure and functional analysis of an archaeal Sm protein complex
    • Full text
    • PDF (654 KB) - RNA binding in an Sm core domain: X-ray structure and functional analysis of an archaeal Sm protein complex

  • SMNrp is an essential pre-mRNA splicing factor required for the formation of the mature spliceosome FREE

    Gunter Meister, Stefan Hannus, Oliver Plöttner, Tonie Baars, Enno Hartmann, Stanislav Fakan, Bernhard Laggerbauer and Utz Fischer

    The EMBO Journal (2001), 20, - 2304 - 2314, doi:10.1093/emboj/20.9.2304

    • Abstract - SMNrp is an essential pre-mRNA splicing factor required for the formation of the mature spliceosome
    • Full text
    • PDF (451 KB) - SMNrp is an essential pre-mRNA splicing factor required for the formation of the mature spliceosome
    • Supplementary information

  • A proline-rich protein binds to the localization element of Xenopus Vg1 mRNA and to ligands involved in actin polymerization FREE

    Wei-meng Zhao, Can Jiang, Todd T. Kroll and Paul W. Huber

    The EMBO Journal (2001), 20, - 2315 - 2325, doi:10.1093/emboj/20.9.2315

    • Abstract - A proline-rich protein binds to the localization element of : Xenopus: Vg1 mRNA and to ligands involved in actin polymerization
    • Full text
    • PDF (294 KB) - A proline-rich protein binds to the localization element of : Xenopus: Vg1 mRNA and to ligands involved in actin polymerization

  • Multiple roles for the C-terminal domain of eIF5 in translation initiation complex assembly and GTPase activation FREE

    Katsura Asano, Anath Shalev, Lon Phan, Klaus Nielsen, Jason Clayton, Leo Valáek, Thomas F. Donahue and Alan G. Hinnebusch

    The EMBO Journal (2001), 20, - 2326 - 2337, doi:10.1093/emboj/20.9.2326

    • Abstract - Multiple roles for the C-terminal domain of eIF5 in translation initiation complex assembly and GTPase activation
    • Full text
    • PDF (593 KB) - Multiple roles for the C-terminal domain of eIF5 in translation initiation complex assembly and GTPase activation

  • SR coordinates signal sequence release from SRP with ribosome binding to the translocon FREE

    Tudor A. Fulga, Irmgard Sinning, Bernhard Dobberstein and Martin R. Pool

    The EMBO Journal (2001), 20, - 2338 - 2347, doi:10.1093/emboj/20.9.2338

    • Abstract - SR[beta] coordinates signal sequence release from SRP with ribosome binding to the translocon
    • Full text
    • PDF (274 KB) - SR[beta] coordinates signal sequence release from SRP with ribosome binding to the translocon
    • Supplementary information

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