Table of Contents : The EMBO Journal

Volume 20, Number 17
03 September 2001

pp 4629-5031

Cover. Pseudo-coloured scanning electron micrographs of a ciliated protozoan, Oxytricha sp. This organism has two types of nuclei, a germinal micronucleus and a somatic macronucleus; the latter is a bag of individual genes, which is an unusual genome organization in eukaryotes. The image shows two protozoa, the larger presumably eating the smaller one; cannibalism is not unusual in this species. Gopal Murti is the Director of Scientific Imaging at St Jude Children's Research Hospital, Memphis, TN, and an adjunct professor of pathology at the University of Tennessee, with research interests in virus--cell interactions and leukaemic cell--stromal cell interactions. He believes that this protozoan, upon which he collaborates with Dr David Prescott, provides an ideal model to study eukaryotic chromosome structure and function.

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New EMBO Members Review
Top of page
- Lysosomal cysteine proteases: facts and opportunities FREE
  Vito Turk, Boris Turk and Duan Turk
  The EMBO Journal (2001), 20, - 4629 - 4633, doi:10.1093/emboj/20.17.4629
- Hsp70 interactions with the p53 tumour suppressor protein FREE
  Maciej Zylicz, Frank W King and Alicja Wawrzynow
  The EMBO Journal (2001), 20, - 4634 - 4638, doi:10.1093/emboj/20.17.4634
  - Full text
  - PDF (124 KB) - Hsp70 interactions with the p53 tumour suppressor protein
Articles
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- Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment FREE
  Eleni Tzima, Miguel Angel del Pozo, Sanford J. Shattil, Shu Chien and Martin Alexander Schwartz
  The EMBO Journal (2001), 20, - 4639 - 4647, doi:10.1093/emboj/20.17.4639
  - Abstract - Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment
  - Full text
  - PDF (301 KB) - Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment
- Expression of Cdc18/Cdc6 and Cdt1 during G₂ phase induces initiation of DNA replication FREE
  Stephanie K. Yanow, Zoi Lygerou and Paul Nurse
  The EMBO Journal (2001), 20, - 4648 - 4656, doi:10.1093/emboj/20.17.4648
  - Abstract - Expression of Cdc18/Cdc6 and Cdt1 during G: 2: phase induces initiation of DNA replication
  - Full text
  - PDF (288 KB) - Expression of Cdc18/Cdc6 and Cdt1 during G: 2: phase induces initiation of DNA replication
- Folded HasA inhibits its own secretion through its ABC exporter FREE
  Laurent Debarbieux and Cécile Wandersman
  The EMBO Journal (2001), 20, - 4657 - 4663, doi:10.1093/emboj/20.17.4657
  - Abstract - Folded HasA inhibits its own secretion through its ABC exporter
  - Full text
  - PDF (167 KB) - Folded HasA inhibits its own secretion through its ABC exporter
- Glide2, a second glial promoting factor in Drosophila melanogaster FREE
  Martial Kammerer and Angela Giangrande
  The EMBO Journal (2001), 20, - 4664 - 4673, doi:10.1093/emboj/20.17.4664
  - Abstract - Glide2, a second glial promoting factor in : Drosophila melanogaster
  - Full text
  - PDF (465 KB) - Glide2, a second glial promoting factor in : Drosophila melanogaster
- RNA interference of a trypanosome topoisomerase II causes progressive loss of mitochondrial DNA FREE
  Zefeng Wang and Paul T. Englund
  The EMBO Journal (2001), 20, - 4674 - 4683, doi:10.1093/emboj/20.17.4674
  - Abstract - RNA interference of a trypanosome topoisomerase II causes progressive loss of mitochondrial DNA
  - Full text
  - PDF (424 KB) - RNA interference of a trypanosome topoisomerase II causes progressive loss of mitochondrial DNA
- Ski7p G protein interacts with the exosome and the Ski complex for 3'-to-5' mRNA decay in yeast FREE
  Yasuhiro Araki, Shinya Takahashi, Tetsuo Kobayashi, Hiroaki Kajiho, Shin-ichi Hoshino and Toshiaki Katada
  The EMBO Journal (2001), 20, - 4684 - 4693, doi:10.1093/emboj/20.17.4684
  - Abstract - Ski7p G protein interacts with the exosome and the Ski complex for 3[prime]-to-5[prime] mRNA decay in yeast
  - Full text
  - PDF (345 KB) - Ski7p G protein interacts with the exosome and the Ski complex for 3[prime]-to-5[prime] mRNA decay in yeast
- Roles for ligases in the RNA editing complex of Trypanosoma brucei: band IV is needed for U-deletion and RNA repair FREE
  Catherine E. Huang, Jorge Cruz-Reyes, Alevtina G. Zhelonkina, Sean O'Hearn, Elizabeth Wirtz and Barbara Sollner-Webb
  The EMBO Journal (2001), 20, - 4694 - 4703, doi:10.1093/emboj/20.17.4694
  - Abstract - Roles for ligases in the RNA editing complex of : Trypanosoma brucei: : band IV is needed for U-deletion and RNA repair
  - Full text
  - PDF (287 KB) - Roles for ligases in the RNA editing complex of : Trypanosoma brucei: : band IV is needed for U-deletion and RNA repair
- Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences FREE
  Andrew Tutt, David Bertwistle, Janet Valentine, Anastasia Gabriel, Sally Swift, Gillian Ross, Carol Griffin, John Thacker and Alan Ashworth
  The EMBO Journal (2001), 20, - 4704 - 4716, doi:10.1093/emboj/20.17.4704
  - Abstract - Mutation in : Brca2: stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences
  - Full text
  - PDF (374 KB) - Mutation in : Brca2: stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences
- The tight interallelic positional coincidence that distinguishes T-cell receptor J usage does not result from homologous chromosomal pairing during VJ rearrangement FREE
  François Davodeau, Michael Difilippantonio, Esther Roldan, Marie Malissen, Jean-Laurent Casanova, Chrystelle Couedel, Jean-François Morcet, Matthias Merkenschlager, André Nussenzweig, Marc Bonneville and Bernard Malissen
  The EMBO Journal (2001), 20, - 4717 - 4729, doi:10.1093/emboj/20.17.4717
  - Abstract - The tight interallelic positional coincidence that distinguishes T-cell receptor J[alpha] usage does not result from homologous chromosomal pairing during V[alpha]J[alpha] rearrangement
  - Full text
  - PDF (836 KB) - The tight interallelic positional coincidence that distinguishes T-cell receptor J[alpha] usage does not result from homologous chromosomal pairing during V[alpha]J[alpha] rearrangement
- Ara6, a plant-unique novel type Rab GTPase, functions in the endocytic pathway of Arabidopsis thaliana FREE
  Takashi Ueda, Masatoshi Yamaguchi, Hirofumi Uchimiya and Akihiko Nakano
  The EMBO Journal (2001), 20, - 4730 - 4741, doi:10.1093/emboj/20.17.4730
  - Abstract - Ara6, a plant-unique novel type Rab GTPase, functions in the endocytic pathway of : Arabidopsis thaliana
  - Full text
  - PDF (477 KB) - Ara6, a plant-unique novel type Rab GTPase, functions in the endocytic pathway of : Arabidopsis thaliana
  - Supplementary information
- NRG1 represses yeast–hypha morphogenesis and hypha-specific gene expression in Candida albicans FREE
  A.Munir A. Murad, Ping Leng, Melissa Straffon, Jill Wishart, Susan Macaskill, Donna MacCallum, Norbert Schnell, Driss Talibi, Daniel Marechal, Fredj Tekaia, Christophe d'Enfert, Claude Gaillardin, Frank C. Odds and Alistair J.P. Brown
  The EMBO Journal (2001), 20, - 4742 - 4752, doi:10.1093/emboj/20.17.4742
  - Abstract - NRG1: represses yeast-hypha morphogenesis and hypha-specific gene expression in : Candida albicans
  - Full text
  - PDF (483 KB) - NRG1: represses yeast-hypha morphogenesis and hypha-specific gene expression in : Candida albicans
- NRG1, a repressor of filamentous growth in C.albicans, is down-regulated during filament induction FREE
  Burkhard R. Braun, David Kadosh and Alexander D. Johnson
  The EMBO Journal (2001), 20, - 4753 - 4761, doi:10.1093/emboj/20.17.4753
  - Abstract - NRG1: , a repressor of filamentous growth in : C.albicans: , is down-regulated during filament induction
  - Full text
  - PDF (351 KB) - NRG1: , a repressor of filamentous growth in : C.albicans: , is down-regulated during filament induction
- Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3 FREE
  Taija Mäkinen, Tanja Veikkola, Satu Mustjoki, Terhi Karpanen, Bruno Catimel, Edouard C. Nice, Lyn Wise, Andrew Mercer, Heinrich Kowalski, Dontscho Kerjaschki, Steven A. Stacker, Marc G. Achen and Kari Alitalo
  The EMBO Journal (2001), 20, - 4762 - 4773, doi:10.1093/emboj/20.17.4762
  - Abstract - Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3
  - Full text
  - PDF (515 KB) - Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3
- Three-dimensional domain swapping in the folded and molten-globule states of cystatins, an amyloid-forming structural superfamily FREE
  Rosemary A. Staniforth, Silva Giannini, Lee D. Higgins, Matthew J. Conroy, Andrea M. Hounslow, Roman Jerala, C. Jeremy Craven and Jonathan P. Waltho
  The EMBO Journal (2001), 20, - 4774 - 4781, doi:10.1093/emboj/20.17.4774
  - Abstract - Three-dimensional domain swapping in the folded and molten-globule states of cystatins, an amyloid-forming structural superfamily
  - Full text
  - PDF (260 KB) - Three-dimensional domain swapping in the folded and molten-globule states of cystatins, an amyloid-forming structural superfamily
- Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion FREE
  Yoshifumi Itoh, Akiko Takamura, Noriko Ito, Yoshiro Maru, Hiroshi Sato, Naoko Suenaga, Takanori Aoki and Motoharu Seiki
  The EMBO Journal (2001), 20, - 4782 - 4793, doi:10.1093/emboj/20.17.4782
  - Abstract - Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion
  - Full text
  - PDF (458 KB) - Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion
- Wobble modification defect in tRNA disturbs codon–anticodon interaction in a mitochondrial disease FREE
  Takehiro Yasukawa, Tsutomu Suzuki, Norie Ishii, Shigeo Ohta and Kimitsuna Watanabe
  The EMBO Journal (2001), 20, - 4794 - 4802, doi:10.1093/emboj/20.17.4794
  - Abstract - Wobble modification defect in tRNA disturbs codon-anticodon interaction in a mitochondrial disease
  - Full text
  - PDF (290 KB) - Wobble modification defect in tRNA disturbs codon-anticodon interaction in a mitochondrial disease
- The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif FREE
  Céline Schaeffer, Barbara Bardoni, Jean-Louis Mandel, Bernard Ehresmann, Chantal Ehresmann and Hervé Moine
  The EMBO Journal (2001), 20, - 4803 - 4813, doi:10.1093/emboj/20.17.4803
  - Abstract - The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif
  - Full text
  - PDF (395 KB) - The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif
  - Supplementary information
- The FK506-binding protein 25 functionally associates with histone deacetylases and with transcription factor YY1 FREE
  Wen-Ming Yang, Ya-Li Yao and Edward Seto
  The EMBO Journal (2001), 20, - 4814 - 4825, doi:10.1093/emboj/20.17.4814
  - Abstract - The FK506-binding protein 25 functionally associates with histone deacetylases and with transcription factor YY1
  - Full text
  - PDF (415 KB) - The FK506-binding protein 25 functionally associates with histone deacetylases and with transcription factor YY1
- Invertebrate connectin spans as much as 3.5 m in the giant sarcomeres of crayfish claw muscle FREE
  Atsushi Fukuzawa, Jinen Shimamura, Shigeru Takemori, Nobuyuki Kanzawa, Maki Yamaguchi, Peng Sun, Koscak Maruyama and Sumiko Kimura
  The EMBO Journal (2001), 20, - 4826 - 4835, doi:10.1093/emboj/20.17.4826
  - Abstract - Invertebrate connectin spans as much as 3.5 [mu]m in the giant sarcomeres of crayfish claw muscle
  - Full text
  - PDF (423 KB) - Invertebrate connectin spans as much as 3.5 [mu]m in the giant sarcomeres of crayfish claw muscle
- Separate SCF^CDC4 recognition elements target Cdc6 for proteolysis in S phase and mitosis FREE
  Gordon Perkins, Lucy S. Drury and John F.X. Diffley
  The EMBO Journal (2001), 20, - 4836 - 4845, doi:10.1093/emboj/20.17.4836
  - Abstract - Separate SCF: CDC4: recognition elements target Cdc6 for proteolysis in S phase and mitosis
  - Full text
  - PDF (308 KB) - Separate SCF: CDC4: recognition elements target Cdc6 for proteolysis in S phase and mitosis
- Translocation within the acceptor helix of a major tRNA identity determinant FREE
  Martha A. Lovato, Joseph W. Chihade and Paul Schimmel
  The EMBO Journal (2001), 20, - 4846 - 4853, doi:10.1093/emboj/20.17.4846
  - Abstract - Translocation within the acceptor helix of a major tRNA identity determinant
  - Full text
  - PDF (291 KB) - Translocation within the acceptor helix of a major tRNA identity determinant
- Repression of bacterial motility by a novel fimbrial gene product FREE
  Xin Li, David A. Rasko, C. Virginia Lockatell, David E. Johnson and Harry L.T. Mobley
  The EMBO Journal (2001), 20, - 4854 - 4862, doi:10.1093/emboj/20.17.4854
  - Abstract - Repression of bacterial motility by a novel fimbrial gene product
  - Full text
  - PDF (393 KB) - Repression of bacterial motility by a novel fimbrial gene product
- Improvement of reading frame maintenance is a common function for several tRNA modifications FREE
  Jaunius Urbonaviius, Qiang Qian, Jérôme M.B. Durand, Tord G. Hagervall and Glenn R. Björk
  The EMBO Journal (2001), 20, - 4863 - 4873, doi:10.1093/emboj/20.17.4863
  - Abstract - Improvement of reading frame maintenance is a common function for several tRNA modifications
  - Full text
  - PDF (375 KB) - Improvement of reading frame maintenance is a common function for several tRNA modifications
- Heterologous, splicing-dependent RNA editing in chloroplasts: allotetraploidy provides trans-factors FREE
  Christian Schmitz-Linneweber, Michael Tillich, Reinhold G. Herrmann and Rainer M. Maier
  The EMBO Journal (2001), 20, - 4874 - 4883, doi:10.1093/emboj/20.17.4874
  - Abstract - Heterologous, splicing-dependent RNA editing in chloroplasts: allotetraploidy provides : trans: -factors
  - Full text
  - PDF (351 KB) - Heterologous, splicing-dependent RNA editing in chloroplasts: allotetraploidy provides : trans: -factors
- Energetic contribution of non-essential 5' sequence to catalysis in a hepatitis delta virus ribozyme FREE
  I.-hung Shih and Michael D. Been
  The EMBO Journal (2001), 20, - 4884 - 4891, doi:10.1093/emboj/20.17.4884
  - Abstract - Energetic contribution of non-essential 5[prime] sequence to catalysis in a hepatitis delta virus ribozyme
  - Full text
  - PDF (228 KB) - Energetic contribution of non-essential 5[prime] sequence to catalysis in a hepatitis delta virus ribozyme
- NoRC—a novel member of mammalian ISWI-containing chromatin remodeling machines FREE
  Ralf Strohner, Attila Nemeth, Petr Jansa, Urs Hofmann-Rohrer, Raffaella Santoro, Gernot Längst and Ingrid Grummt
  The EMBO Journal (2001), 20, - 4892 - 4900, doi:10.1093/emboj/20.17.4892
  - Abstract - NoRC[mdash]a novel member of mammalian ISWI-containing chromatin remodeling machines
  - Full text
  - PDF (281 KB) - NoRC[mdash]a novel member of mammalian ISWI-containing chromatin remodeling machines
- Probing the ATP-binding site of P1 ParA: partition and repression have different requirements for ATP binding and hydrolysis FREE
  Emma Fung, Jean-Yves Bouet and Barbara E. Funnell
  The EMBO Journal (2001), 20, - 4901 - 4911, doi:10.1093/emboj/20.17.4901
  - Abstract - Probing the ATP-binding site of P1 ParA: partition and repression have different requirements for ATP binding and hydrolysis
  - Full text
  - PDF (396 KB) - Probing the ATP-binding site of P1 ParA: partition and repression have different requirements for ATP binding and hydrolysis
- Deregulated -catenin induces a p53- and ARF-dependent growth arrest and cooperates with Ras in transformation FREE
  Alexander Damalas, Sharon Kahan, Michael Shtutman, Avri Ben-Ze'ev and Moshe Oren
  The EMBO Journal (2001), 20, - 4912 - 4922, doi:10.1093/emboj/20.17.4912
  - Abstract - Deregulated [beta]-catenin induces a p53- and ARF-dependent growth arrest and cooperates with Ras in transformation
  - Full text
  - PDF (515 KB) - Deregulated [beta]-catenin induces a p53- and ARF-dependent growth arrest and cooperates with Ras in transformation
- Purification, cloning and characterization of a GPI inositol deacylase from Trypanosoma brucei FREE
  Maria Lucia Sampaio Güther, Simone Leal, Nicholas A. Morrice, George A.M. Cross and Michael A.J. Ferguson
  The EMBO Journal (2001), 20, - 4923 - 4934, doi:10.1093/emboj/20.17.4923
  - Abstract - Purification, cloning and characterization of a GPI inositol deacylase from : Trypanosoma brucei
  - Full text
  - PDF (550 KB) - Purification, cloning and characterization of a GPI inositol deacylase from : Trypanosoma brucei
- The chromatin remodelling factor Brg-1 interacts with -catenin to promote target gene activation FREE
  Nick Barker, Adam Hurlstone, Hannah Musisi, Antony Miles, Mariann Bienz and Hans Clevers
  The EMBO Journal (2001), 20, - 4935 - 4943, doi:10.1093/emboj/20.17.4935
  - Abstract - The chromatin remodelling factor Brg-1 interacts with [beta]-catenin to promote target gene activation
  - Full text
  - PDF (325 KB) - The chromatin remodelling factor Brg-1 interacts with [beta]-catenin to promote target gene activation
- Increasing the rate of chromatin remodeling and gene activation—a novel role for the histone acetyltransferase Gcn5 FREE
  S. Barbaric, J. Walker, A. Schmid, J.Q. Svejstrup and W. Hörz
  The EMBO Journal (2001), 20, - 4944 - 4951, doi:10.1093/emboj/20.17.4944
  - Abstract - Increasing the rate of chromatin remodeling and gene activation[mdash]a novel role for the histone acetyltransferase Gcn5
  - Full text
  - PDF (243 KB) - Increasing the rate of chromatin remodeling and gene activation[mdash]a novel role for the histone acetyltransferase Gcn5
- A moving DNA replication factory in Caulobacter crescentus FREE
  Rasmus B. Jensen, Sherry C. Wang and Lucy Shapiro
  The EMBO Journal (2001), 20, - 4952 - 4963, doi:10.1093/emboj/20.17.4952
  - Abstract - A moving DNA replication factory in : Caulobacter crescentus
  - Full text
  - PDF (458 KB) - A moving DNA replication factory in : Caulobacter crescentus
  - Supplementary information
- Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing FREE
  Rachelle Gaudet and Don C. Wiley
  The EMBO Journal (2001), 20, - 4964 - 4972, doi:10.1093/emboj/20.17.4964
  - Abstract - Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing
  - Full text
  - PDF (579 KB) - Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing
- An essential role for ARF6-regulated membrane traffic in adherens junction turnover and epithelial cell migration FREE
  Felipe Palacios, Leo Price, Jill Schweitzer, John G. Collard and Crislyn D'Souza-Schorey
  The EMBO Journal (2001), 20, - 4973 - 4986, doi:10.1093/emboj/20.17.4973
  - Abstract - An essential role for ARF6-regulated membrane traffic in adherens junction turnover and epithelial cell migration
  - Full text
  - PDF (714 KB) - An essential role for ARF6-regulated membrane traffic in adherens junction turnover and epithelial cell migration
- The exon–exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay FREE
  Hervé Le Hir, David Gatfield, Elisa Izaurralde and Melissa J. Moore
  The EMBO Journal (2001), 20, - 4987 - 4997, doi:10.1093/emboj/20.17.4987
  - Abstract - The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay
  - Full text
  - PDF (446 KB) - The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay
- Beat-to-beat oscillations of mitochondrial [Ca²⁺] in cardiac cells FREE
  Valérie Robert, Pamela Gurlini, Valeria Tosello, Takeharu Nagai, Atsushi Miyawaki, Fabio Di Lisa and Tullio Pozzan
  The EMBO Journal (2001), 20, - 4998 - 5007, doi:10.1093/emboj/20.17.4998
  - Abstract - Beat-to-beat oscillations of mitochondrial [Ca: 2+: ] in cardiac cells
  - Full text
  - PDF (561 KB) - Beat-to-beat oscillations of mitochondrial [Ca: 2+: ] in cardiac cells
- Hrs recruits clathrin to early endosomes FREE
  Camilla Raiborg, Kristi Grønvold Bache, Anja Mehlum, Espen Stang and Harald Stenmark
  The EMBO Journal (2001), 20, - 5008 - 5021, doi:10.1093/emboj/20.17.5008
  - Abstract - Hrs recruits clathrin to early endosomes
  - Full text
  - PDF (724 KB) - Hrs recruits clathrin to early endosomes
- The Usf-1 transcription factor is a novel target for the stress-responsive p38 kinase and mediates UV-induced Tyrosinase expression FREE
  Marie-Dominique Galibert, Suzanne Carreira and Colin R. Goding
  The EMBO Journal (2001), 20, - 5022 - 5031, doi:10.1093/emboj/20.17.5022
  - Abstract - The Usf-1 transcription factor is a novel target for the stress-responsive p38 kinase and mediates UV-induced : Tyrosinase: expression
  - Full text
  - PDF (261 KB) - The Usf-1 transcription factor is a novel target for the stress-responsive p38 kinase and mediates UV-induced : Tyrosinase: expression

Table of Contents

Volume 20, Number 17 03 September 2001

New EMBO Members Review

Lysosomal cysteine proteases: facts and opportunities FREE

Hsp70 interactions with the p53 tumour suppressor protein FREE

Articles

Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment FREE

Expression of Cdc18/Cdc6 and Cdt1 during G2 phase induces initiation of DNA replication FREE

Folded HasA inhibits its own secretion through its ABC exporter FREE

Glide2, a second glial promoting factor in Drosophila melanogaster FREE

RNA interference of a trypanosome topoisomerase II causes progressive loss of mitochondrial DNA FREE

Ski7p G protein interacts with the exosome and the Ski complex for 3'-to-5' mRNA decay in yeast FREE

Roles for ligases in the RNA editing complex of Trypanosoma brucei: band IV is needed for U-deletion and RNA repair FREE

Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences FREE

The tight interallelic positional coincidence that distinguishes T-cell receptor J usage does not result from homologous chromosomal pairing during VJ rearrangement FREE

Ara6, a plant-unique novel type Rab GTPase, functions in the endocytic pathway of Arabidopsis thaliana FREE

NRG1 represses yeast–hypha morphogenesis and hypha-specific gene expression in Candida albicans FREE

NRG1, a repressor of filamentous growth in C.albicans, is down-regulated during filament induction FREE

Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3 FREE

Three-dimensional domain swapping in the folded and molten-globule states of cystatins, an amyloid-forming structural superfamily FREE

Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion FREE

Wobble modification defect in tRNA disturbs codon–anticodon interaction in a mitochondrial disease FREE

The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif FREE

The FK506-binding protein 25 functionally associates with histone deacetylases and with transcription factor YY1 FREE

Invertebrate connectin spans as much as 3.5 m in the giant sarcomeres of crayfish claw muscle FREE

Separate SCFCDC4 recognition elements target Cdc6 for proteolysis in S phase and mitosis FREE

Translocation within the acceptor helix of a major tRNA identity determinant FREE

Repression of bacterial motility by a novel fimbrial gene product FREE

Improvement of reading frame maintenance is a common function for several tRNA modifications FREE

Heterologous, splicing-dependent RNA editing in chloroplasts: allotetraploidy provides trans-factors FREE

Energetic contribution of non-essential 5' sequence to catalysis in a hepatitis delta virus ribozyme FREE

NoRC—a novel member of mammalian ISWI-containing chromatin remodeling machines FREE

Probing the ATP-binding site of P1 ParA: partition and repression have different requirements for ATP binding and hydrolysis FREE

Deregulated -catenin induces a p53- and ARF-dependent growth arrest and cooperates with Ras in transformation FREE

Purification, cloning and characterization of a GPI inositol deacylase from Trypanosoma brucei FREE

The chromatin remodelling factor Brg-1 interacts with -catenin to promote target gene activation FREE

Increasing the rate of chromatin remodeling and gene activation—a novel role for the histone acetyltransferase Gcn5 FREE

A moving DNA replication factory in Caulobacter crescentus FREE

Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing FREE

An essential role for ARF6-regulated membrane traffic in adherens junction turnover and epithelial cell migration FREE

The exon–exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay FREE

Beat-to-beat oscillations of mitochondrial [Ca2+] in cardiac cells FREE

Hrs recruits clathrin to early endosomes FREE

The Usf-1 transcription factor is a novel target for the stress-responsive p38 kinase and mediates UV-induced Tyrosinase expression FREE

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Volume 20, Number 17
03 September 2001

Expression of Cdc18/Cdc6 and Cdt1 during G₂ phase induces initiation of DNA replication FREE

Separate SCF^CDC4 recognition elements target Cdc6 for proteolysis in S phase and mitosis FREE

Beat-to-beat oscillations of mitochondrial [Ca²⁺] in cardiac cells FREE