Table of Contents : The EMBO Journal

Volume 20, Number 15
01 August 2001

pp 3893-4323

Cover. The image shows the top view of the docking between the three-dimensional reconstruction of the chaperonin CCT incubated with AMP-PNP (yellow grid) and the X-ray structure of the thermosome (in purple and white; Ditzel et al., 1998). Dr J.M.Valpuesta is a Research Scientist of the Spanish Research Council (CSIC) and works at the Electron Microscopy Unit, Centro Nacional de Biotecnologia, Madrid. His current research involves the study of the structure--function relationship of the eukaryotic chaperonin CCT and its role in the folding of substrates such as actin and tubulin. For further details, see Llorca et al., pages 4065--4075.

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New EMBO Members Review
Top of page
- Cell surface monoamine oxidases: enzymes in search of a function FREE
  S. Jalkanen and M. Salmi
  The EMBO Journal (2001), 20, - 3893 - 3901, doi:10.1093/emboj/20.15.3893
Articles
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- Mycobacterium tuberculosis hemoglobin N displays a protein tunnel suited for O₂ diffusion to the heme FREE
  Mario Milani, Alessandra Pesce, Yannick Ouellet, Paolo Ascenzi, Michel Guertin and Martino Bolognesi
  The EMBO Journal (2001), 20, - 3902 - 3909, doi:10.1093/emboj/20.15.3902
  - Abstract - Mycobacterium tuberculosis: hemoglobin N displays a protein tunnel suited for O: 2: diffusion to the heme
  - Full text
  - PDF (366 KB) - Mycobacterium tuberculosis: hemoglobin N displays a protein tunnel suited for O: 2: diffusion to the heme
- Structure of human cystathionine -synthase: a unique pyridoxal 5'-phosphate-dependent heme protein FREE
  Markus Meier, Miroslav Janosik, Vladimir Kery, Jan P. Kraus and Peter Burkhard
  The EMBO Journal (2001), 20, - 3910 - 3916, doi:10.1093/emboj/20.15.3910
  - Abstract - Structure of human cystathionine [beta]-synthase: a unique pyridoxal 5[prime]-phosphate-dependent heme protein
  - Full text
  - PDF (346 KB) - Structure of human cystathionine [beta]-synthase: a unique pyridoxal 5[prime]-phosphate-dependent heme protein
- X-ray structure of HPr kinase: a bacterial protein kinase with a P-loop nucleotide-binding domain FREE
  Sonia Fieulaine, Solange Morera, Sandrine Poncet, Vicente Monedero, Virginie Gueguen-Chaignon, Anne Galinier, Joël Janin, Josef Deutscher and Sylvie Nessler
  The EMBO Journal (2001), 20, - 3917 - 3927, doi:10.1093/emboj/20.15.3917
  - Abstract - X-ray structure of HPr kinase: a bacterial protein kinase with a P-loop nucleotide-binding domain
  - Full text
  - PDF (604 KB) - X-ray structure of HPr kinase: a bacterial protein kinase with a P-loop nucleotide-binding domain
- Mutations lowering the phosphatase activity of HPr kinase/phosphatase switch off carbon metabolism FREE
  Vicente Monedero, Sandrine Poncet, Ivan Mijakovic, Sonia Fieulaine, Valérie Dossonnet, Isabelle Martin-Verstraete, Sylvie Nessler and Josef Deutscher
  The EMBO Journal (2001), 20, - 3928 - 3937, doi:10.1093/emboj/20.15.3928
  - Abstract - Mutations lowering the phosphatase activity of HPr kinase/phosphatase switch off carbon metabolism
  - Full text
  - PDF (280 KB) - Mutations lowering the phosphatase activity of HPr kinase/phosphatase switch off carbon metabolism
- Novel modular domain PB1 recognizes PC motif to mediate functional protein–protein interactions FREE
  Takashi Ito, Yasushi Matsui, Tetsuro Ago, Kazuhisa Ota and Hideki Sumimoto
  The EMBO Journal (2001), 20, - 3938 - 3946, doi:10.1093/emboj/20.15.3938
  - Abstract - Novel modular domain PB1 recognizes PC motif to mediate functional protein-protein interactions
  - Full text
  - PDF (421 KB) - Novel modular domain PB1 recognizes PC motif to mediate functional protein-protein interactions
- Structure and ligand recognition of the PB1 domain: a novel protein module binding to the PC motif FREE
  Hiroaki Terasawa, Yukiko Noda, Takashi Ito, Hideki Hatanaka, Saori Ichikawa, Kenji Ogura, Hideki Sumimoto and Fuyuhiko Inagaki
  The EMBO Journal (2001), 20, - 3947 - 3956, doi:10.1093/emboj/20.15.3947
  - Abstract - Structure and ligand recognition of the PB1 domain: a novel protein module binding to the PC motif
  - Full text
  - PDF (526 KB) - Structure and ligand recognition of the PB1 domain: a novel protein module binding to the PC motif
- Intracellular re-routing of prion protein prevents propagation of PrP^Sc and delays onset of prion disease FREE
  Sabine Gilch, Konstanze F. Winklhofer, Martin H. Groschup, Max Nunziante, Ralf Lucassen, Christian Spielhaupter, Walter Muranyi, Detlev Riesner, Jörg Tatzelt and Hermann M. Schätzl
  The EMBO Journal (2001), 20, - 3957 - 3966, doi:10.1093/emboj/20.15.3957
  - Abstract - Intracellular re-routing of prion protein prevents propagation of PrP: Sc: and delays onset of prion disease
  - Full text
  - PDF (298 KB) - Intracellular re-routing of prion protein prevents propagation of PrP: Sc: and delays onset of prion disease
- Altered behavioral rhythms and clock gene expression in mice with a targeted mutation in the Period1 gene FREE
  Nicolas Cermakian, Lucia Monaco, Matthew P. Pando, Andrée Dierich and Paolo Sassone-Corsi
  The EMBO Journal (2001), 20, - 3967 - 3974, doi:10.1093/emboj/20.15.3967
  - Abstract - Altered behavioral rhythms and clock gene expression in mice with a targeted mutation in the : Period1: gene
  - Full text
  - PDF (404 KB) - Altered behavioral rhythms and clock gene expression in mice with a targeted mutation in the : Period1: gene
- P25 and P28 proteins of the malaria ookinete surface have multiple and partially redundant functions FREE
  Ana M. Tomas, Gabriele Margos, George Dimopoulos, Leo H.M. van Lin, Tania F. de Koning-Ward, Ria Sinha, Pietro Lupetti, Annette L. Beetsma, Maria C. Rodriguez, Marianna Karras, Ariadne Hager, Jacqui Mendoza, Geoffrey A. Butcher, Fotis Kafatos, Chris J. Janse, Andrew P. Waters and Robert E. Sinden
  The EMBO Journal (2001), 20, - 3975 - 3983, doi:10.1093/emboj/20.15.3975
  - Abstract - P25 and P28 proteins of the malaria ookinete surface have multiple and partially redundant functions
  - Full text
  - PDF (197 KB) - P25 and P28 proteins of the malaria ookinete surface have multiple and partially redundant functions
- Roles for 147 embryonic lethal genes on C.elegans chromosome I identified by RNA interference and video microscopy FREE
  Peder Zipperlen, Andrew G. Fraser, Ravi S. Kamath, Maruxa Martinez-Campos and Julie Ahringer
  The EMBO Journal (2001), 20, - 3984 - 3992, doi:10.1093/emboj/20.15.3984
  - Abstract - Roles for 147 embryonic lethal genes on : C.elegans: chromosome I identified by RNA interference and video microscopy
  - Full text
  - PDF (966 KB) - Roles for 147 embryonic lethal genes on : C.elegans: chromosome I identified by RNA interference and video microscopy
  - Supplementary information
- CHIF, a member of the FXYD protein family, is a regulator of Na,K-ATPase distinct from the -subunit FREE
  Pascal Béguin, Gilles Crambert, Saida Guennoun, Haim Garty, Jean-Daniel Horisberger and Käthi Geering
  The EMBO Journal (2001), 20, - 3993 - 4002, doi:10.1093/emboj/20.15.3993
  - Abstract - CHIF, a member of the FXYD protein family, is a regulator of Na,K-ATPase distinct from the [gamma]-subunit
  - Full text
  - PDF (388 KB) - CHIF, a member of the FXYD protein family, is a regulator of Na,K-ATPase distinct from the [gamma]-subunit
- NEDD8 recruits E2-ubiquitin to SCF E3 ligase FREE
  Takayuki Kawakami, Tomoki Chiba, Toshiaki Suzuki, Kazuhiro Iwai, Koji Yamanaka, Nagahiro Minato, Hiroshi Suzuki, Naoki Shimbara, Yuko Hidaka, Fumio Osaka, Masao Omata and Keiji Tanaka
  The EMBO Journal (2001), 20, - 4003 - 4012, doi:10.1093/emboj/20.15.4003
  - Abstract - NEDD8 recruits E2-ubiquitin to SCF E3 ligase
  - Full text
  - PDF (360 KB) - NEDD8 recruits E2-ubiquitin to SCF E3 ligase
- Dephosphorylation of 2-syntrophin and Ca²⁺/-calpain-mediated cleavage of ICA512 upon stimulation of insulin secretion FREE
  Tatiana Ort, Sergei Voronov, Jun Guo, Kathleen Zawalich, Stanley C. Froehner, Walter Zawalich and Michele Solimena
  The EMBO Journal (2001), 20, - 4013 - 4023, doi:10.1093/emboj/20.15.4013
  - Abstract - Dephosphorylation of [beta]2-syntrophin and Ca: 2+: /[mu]-calpain-mediated cleavage of ICA512 upon stimulation of insulin secretion
  - Full text
  - PDF (361 KB) - Dephosphorylation of [beta]2-syntrophin and Ca: 2+: /[mu]-calpain-mediated cleavage of ICA512 upon stimulation of insulin secretion
- Membrane fusion machines of paramyxoviruses: capture of intermediates of fusion FREE
  Charles J. Russell, Theodore S. Jardetzky and Robert A. Lamb
  The EMBO Journal (2001), 20, - 4024 - 4034, doi:10.1093/emboj/20.15.4024
  - Abstract - Membrane fusion machines of paramyxoviruses: capture of intermediates of fusion
  - Full text
  - PDF (429 KB) - Membrane fusion machines of paramyxoviruses: capture of intermediates of fusion
- Ergosterol is required for the Sec18/ATP-dependent priming step of homotypic vacuole fusion FREE
  Masashi Kato and William Wickner
  The EMBO Journal (2001), 20, - 4035 - 4040, doi:10.1093/emboj/20.15.4035
  - Abstract - Ergosterol is required for the Sec18/ATP-dependent priming step of homotypic vacuole fusion
  - Full text
  - PDF (223 KB) - Ergosterol is required for the Sec18/ATP-dependent priming step of homotypic vacuole fusion
- Mammalian Golgi-associated Bicaudal-D2 functions in the dynein–dynactin pathway by interacting with these complexes FREE
  Casper C. Hoogenraad, Anna Akhmanova, Steven A. Howell, Bjorn R. Dortland, Chris I. De Zeeuw, Rob Willemsen, Pim Visser, Frank Grosveld and Niels Galjart
  The EMBO Journal (2001), 20, - 4041 - 4054, doi:10.1093/emboj/20.15.4041
  - Abstract - Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes
  - Full text
  - PDF (799 KB) - Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes
- The p41 isoform of invariant chain is a chaperone for cathepsin L FREE
  Ana-Maria Lennon-Duménil, Rebecca A. Roberts, Karine Valentijn, Christoph Driessen, Herman S. Overkleeft, Ann Erickson, Peter J. Peters, Elizabeth Bikoff, Hidde L. Ploegh and Paula Wolf Bryant
  The EMBO Journal (2001), 20, - 4055 - 4064, doi:10.1093/emboj/20.15.4055
  - Abstract - The p41 isoform of invariant chain is a chaperone for cathepsin L
  - Full text
  - PDF (337 KB) - The p41 isoform of invariant chain is a chaperone for cathepsin L
- The 'sequential allosteric ring' mechanism in the eukaryotic chaperonin-assisted folding of actin and tubulin FREE
  Oscar Llorca, Jaime Martín-Benito, Julie Grantham, Monica Ritco-Vonsovici, Keith R. Willison, José L. Carrascosa and José M. Valpuesta
  The EMBO Journal (2001), 20, - 4065 - 4075, doi:10.1093/emboj/20.15.4065
  - Abstract - The 'sequential allosteric ring' mechanism in the eukaryotic chaperonin-assisted folding of actin and tubulin
  - Full text
  - PDF (414 KB) - The 'sequential allosteric ring' mechanism in the eukaryotic chaperonin-assisted folding of actin and tubulin
- The Ras-like GTPase Gem is involved in cell shape remodelling and interacts with the novel kinesin-like protein KIF9 FREE
  Eugenia Piddini, Johannes A. Schmid, Rainer de Martin and Carlos G. Dotti
  The EMBO Journal (2001), 20, - 4076 - 4087, doi:10.1093/emboj/20.15.4076
  - Abstract - The Ras-like GTPase Gem is involved in cell shape remodelling and interacts with the novel kinesin-like protein KIF9
  - Full text
  - PDF (587 KB) - The Ras-like GTPase Gem is involved in cell shape remodelling and interacts with the novel kinesin-like protein KIF9
  - Supplementary information
- PIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8 FREE
  Kazuhito Ohishi, Norimitsu Inoue and Taroh Kinoshita
  The EMBO Journal (2001), 20, - 4088 - 4098, doi:10.1093/emboj/20.15.4088
  - Abstract - PIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8
  - Full text
  - PDF (673 KB) - PIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8
- Functional reconstitution of the import of the yeast ADP/ATP carrier mediated by the TIM10 complex FREE
  P. Luciano, S. Vial, M.A.S. Vergnolle, S.D. Dyall, D.R. Robinson and K. Tokatlidis
  The EMBO Journal (2001), 20, - 4099 - 4106, doi:10.1093/emboj/20.15.4099
  - Abstract - Functional reconstitution of the import of the yeast ADP/ATP carrier mediated by the TIM10 complex
  - Full text
  - PDF (201 KB) - Functional reconstitution of the import of the yeast ADP/ATP carrier mediated by the TIM10 complex
- Propagation of the apoptotic signal by mitochondrial waves FREE
  Pál Pacher and György Hajnóczky
  The EMBO Journal (2001), 20, - 4107 - 4121, doi:10.1093/emboj/20.15.4107
  - Abstract - Propagation of the apoptotic signal by mitochondrial waves
  - Full text
  - PDF (1,042 KB) - Propagation of the apoptotic signal by mitochondrial waves
- Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus FREE
  Xinghai Li, H.Joseph Yost, David M. Virshup and Joni M. Seeling
  The EMBO Journal (2001), 20, - 4122 - 4131, doi:10.1093/emboj/20.15.4122
  - Abstract - Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in : Xenopus
  - Full text
  - PDF (404 KB) - Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in : Xenopus
- Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads FREE
  Fumiko Itoh, Hironobu Asao, Kazuo Sugamura, Carl-Henrik Heldin, Peter ten Dijke and Susumu Itoh
  The EMBO Journal (2001), 20, - 4132 - 4142, doi:10.1093/emboj/20.15.4132
  - Abstract - Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads
  - Full text
  - PDF (372 KB) - Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads
- The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1 FREE
  Ralph Tiedt, Boris A. Bartholdy, Gabriele Matthias, John W. Newell and Patrick Matthias
  The EMBO Journal (2001), 20, - 4143 - 4152, doi:10.1093/emboj/20.15.4143
  - Abstract - The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1
  - Full text
  - PDF (285 KB) - The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1
- Regulation of BOB.1/OBF.1 stability by SIAH FREE
  Jannic Boehm, Yunsheng He, Axel Greiner, Louis Staudt and Thomas Wirth
  The EMBO Journal (2001), 20, - 4153 - 4162, doi:10.1093/emboj/20.15.4153
  - Abstract - Regulation of BOB.1/OBF.1 stability by SIAH
  - Full text
  - PDF (302 KB) - Regulation of BOB.1/OBF.1 stability by SIAH
- Integrity of the N-terminal transcription domain of p53 is required for mutant p53 interference with drug-induced apoptosis FREE
  Devorah Matas, Alex Sigal, Perry Stambolsky, Michael Milyavsky, Lilach Weisz, Dov Schwartz, Naomi Goldfinger and Varda Rotter
  The EMBO Journal (2001), 20, - 4163 - 4172, doi:10.1093/emboj/20.15.4163
  - Abstract - Integrity of the N-terminal transcription domain of p53 is required for mutant p53 interference with drug-induced apoptosis
  - Full text
  - PDF (259 KB) - Integrity of the N-terminal transcription domain of p53 is required for mutant p53 interference with drug-induced apoptosis
- Polymerization of the SAM domain of TEL in leukemogenesis and transcriptional repression FREE
  Chongwoo A. Kim, Martin L. Phillips, Woojae Kim, Mari Gingery, Hoang H. Tran, Michael A. Robinson, Salem Faham and James U. Bowie
  The EMBO Journal (2001), 20, - 4173 - 4182, doi:10.1093/emboj/20.15.4173
  - Abstract - Polymerization of the SAM domain of TEL in leukemogenesis and transcriptional repression
  - Full text
  - PDF (475 KB) - Polymerization of the SAM domain of TEL in leukemogenesis and transcriptional repression
- An essential nuclear envelope integral membrane protein, Brr6p, required for nuclear transport FREE
  Anne de Bruyn Kops and Christine Guthrie
  The EMBO Journal (2001), 20, - 4183 - 4193, doi:10.1093/emboj/20.15.4183
  - Abstract - An essential nuclear envelope integral membrane protein, Brr6p, required for nuclear transport
  - Full text
  - PDF (325 KB) - An essential nuclear envelope integral membrane protein, Brr6p, required for nuclear transport
  - Supplementary information
- Regulation of alternative pre-mRNA splicing by the ERK MAP-kinase pathway FREE
  Susanne Weg-Remers, Helmut Ponta, Peter Herrlich and Harald König
  The EMBO Journal (2001), 20, - 4194 - 4203, doi:10.1093/emboj/20.15.4194
  - Abstract - Regulation of alternative pre-mRNA splicing by the ERK MAP-kinase pathway
  - Full text
  - PDF (370 KB) - Regulation of alternative pre-mRNA splicing by the ERK MAP-kinase pathway
- Processing of 20S pre-rRNA to 18S ribosomal RNA in yeast requires Rrp10p, an essential non-ribosomal cytoplasmic protein FREE
  Emmanuel Vanrobays, Pierre-Emmanuel Gleizes, Cécile Bousquet-Antonelli, Jacqueline Noaillac-Depeyre, Michèle Caizergues-Ferrer and Jean-Paul Gélugne
  The EMBO Journal (2001), 20, - 4204 - 4213, doi:10.1093/emboj/20.15.4204
  - Abstract - Processing of 20S pre-rRNA to 18S ribosomal RNA in yeast requires Rrp10p, an essential non-ribosomal cytoplasmic protein
  - Full text
  - PDF (318 KB) - Processing of 20S pre-rRNA to 18S ribosomal RNA in yeast requires Rrp10p, an essential non-ribosomal cytoplasmic protein
  - Supplementary information
- The kink-turn: a new RNA secondary structure motif FREE
  D.J. Klein, T.M. Schmeing, P.B. Moore and T.A. Steitz
  The EMBO Journal (2001), 20, - 4214 - 4221, doi:10.1093/emboj/20.15.4214
  - Abstract - The kink-turn: a new RNA secondary structure motif
  - Full text
  - PDF (454 KB) - The kink-turn: a new RNA secondary structure motif
- Non-canonical mechanism for translational control in bacteria: synthesis of ribosomal protein S1 FREE
  Irina V. Boni, Valentina S. Artamonova, Nina V. Tzareva and Marc Dreyfus
  The EMBO Journal (2001), 20, - 4222 - 4232, doi:10.1093/emboj/20.15.4222
  - Abstract - Non-canonical mechanism for translational control in bacteria: synthesis of ribosomal protein S1
  - Full text
  - PDF (391 KB) - Non-canonical mechanism for translational control in bacteria: synthesis of ribosomal protein S1
- Truncated initiation factor eIF4G lacking an eIF4E binding site can support capped mRNA translation FREE
  Iraj K. Ali, Linda McKendrick, Simon J. Morley and Richard J. Jackson
  The EMBO Journal (2001), 20, - 4233 - 4242, doi:10.1093/emboj/20.15.4233
  - Abstract - Truncated initiation factor eIF4G lacking an eIF4E binding site can support capped mRNA translation
  - Full text
  - PDF (247 KB) - Truncated initiation factor eIF4G lacking an eIF4E binding site can support capped mRNA translation
- Specific cleavage of hyper-edited dsRNAs FREE
  A.D.J. Scadden and Christopher W.J. Smith
  The EMBO Journal (2001), 20, - 4243 - 4252, doi:10.1093/emboj/20.15.4243
  - Abstract - Specific cleavage of hyper-edited dsRNAs
  - Full text
  - PDF (305 KB) - Specific cleavage of hyper-edited dsRNAs
  - Supplementary information
- Hda, a novel DnaA-related protein, regulates the replication cycle in Escherichia coli FREE
  Jun-ichi Kato and Tsutomu Katayama
  The EMBO Journal (2001), 20, - 4253 - 4262, doi:10.1093/emboj/20.15.4253
  - Abstract - Hda, a novel DnaA-related protein, regulates the replication cycle in : Escherichia coli
  - Full text
  - PDF (311 KB) - Hda, a novel DnaA-related protein, regulates the replication cycle in : Escherichia coli
- Stability, chromatin association and functional activity of mammalian pre-replication complex proteins during the cell cycle FREE
  Yukiko Okuno, Adrian J. McNairn, Nicole den Elzen, Jonathon Pines and David M. Gilbert
  The EMBO Journal (2001), 20, - 4263 - 4277, doi:10.1093/emboj/20.15.4263
  - Abstract - Stability, chromatin association and functional activity of mammalian pre-replication complex proteins during the cell cycle
  - Full text
  - PDF (501 KB) - Stability, chromatin association and functional activity of mammalian pre-replication complex proteins during the cell cycle
- Excision of deaminated cytosine from the vertebrate genome: role of the SMUG1 uracil–DNA glycosylase FREE
  Hilde Nilsen, Karl A. Haushalter, Peter Robins, Deborah E. Barnes, Gregory L. Verdine and Tomas Lindahl
  The EMBO Journal (2001), 20, - 4278 - 4286, doi:10.1093/emboj/20.15.4278
  - Abstract - Excision of deaminated cytosine from the vertebrate genome: role of the SMUG1 uracil-DNA glycosylase
  - Full text
  - PDF (395 KB) - Excision of deaminated cytosine from the vertebrate genome: role of the SMUG1 uracil-DNA glycosylase
- Converting a DNA damage checkpoint effector (UmuD₂C) into a lesion bypass polymerase (UmuD'₂C) FREE
  Ann E. Ferentz, Graham C. Walker and Gerhard Wagner
  The EMBO Journal (2001), 20, - 4287 - 4298, doi:10.1093/emboj/20.15.4287
  - Abstract - Converting a DNA damage checkpoint effector (UmuD: 2: C) into a lesion bypass polymerase (UmuD[prime]: 2: C)
  - Full text
  - PDF (564 KB) - Converting a DNA damage checkpoint effector (UmuD: 2: C) into a lesion bypass polymerase (UmuD[prime]: 2: C)
- G-overhang dynamics at Tetrahymena telomeres FREE
  Naduparambil K. Jacob, Rose Skopp and Carolyn M. Price
  The EMBO Journal (2001), 20, - 4299 - 4308, doi:10.1093/emboj/20.15.4299
  - Abstract - G-overhang dynamics at : Tetrahymena: telomeres
  - Full text
  - PDF (289 KB) - G-overhang dynamics at : Tetrahymena: telomeres
- dim-2 encodes a DNA methyltransferase responsible for all known cytosine methylation in Neurospora FREE
  Elena Kouzminova and Eric U. Selker
  The EMBO Journal (2001), 20, - 4309 - 4323, doi:10.1093/emboj/20.15.4309
  - Abstract - dim-2: encodes a DNA methyltransferase responsible for all known cytosine methylation in : Neurospora
  - Full text
  - PDF (552 KB) - dim-2: encodes a DNA methyltransferase responsible for all known cytosine methylation in : Neurospora

Table of Contents

Volume 20, Number 15 01 August 2001

New EMBO Members Review

Cell surface monoamine oxidases: enzymes in search of a function FREE

Articles

Mycobacterium tuberculosis hemoglobin N displays a protein tunnel suited for O2 diffusion to the heme FREE

Structure of human cystathionine -synthase: a unique pyridoxal 5'-phosphate-dependent heme protein FREE

X-ray structure of HPr kinase: a bacterial protein kinase with a P-loop nucleotide-binding domain FREE

Mutations lowering the phosphatase activity of HPr kinase/phosphatase switch off carbon metabolism FREE

Novel modular domain PB1 recognizes PC motif to mediate functional protein–protein interactions FREE

Structure and ligand recognition of the PB1 domain: a novel protein module binding to the PC motif FREE

Intracellular re-routing of prion protein prevents propagation of PrPSc and delays onset of prion disease FREE

Altered behavioral rhythms and clock gene expression in mice with a targeted mutation in the Period1 gene FREE

P25 and P28 proteins of the malaria ookinete surface have multiple and partially redundant functions FREE

Roles for 147 embryonic lethal genes on C.elegans chromosome I identified by RNA interference and video microscopy FREE

CHIF, a member of the FXYD protein family, is a regulator of Na,K-ATPase distinct from the -subunit FREE

NEDD8 recruits E2-ubiquitin to SCF E3 ligase FREE

Dephosphorylation of 2-syntrophin and Ca2+/-calpain-mediated cleavage of ICA512 upon stimulation of insulin secretion FREE

Membrane fusion machines of paramyxoviruses: capture of intermediates of fusion FREE

Ergosterol is required for the Sec18/ATP-dependent priming step of homotypic vacuole fusion FREE

Mammalian Golgi-associated Bicaudal-D2 functions in the dynein–dynactin pathway by interacting with these complexes FREE

The p41 isoform of invariant chain is a chaperone for cathepsin L FREE

The 'sequential allosteric ring' mechanism in the eukaryotic chaperonin-assisted folding of actin and tubulin FREE

The Ras-like GTPase Gem is involved in cell shape remodelling and interacts with the novel kinesin-like protein KIF9 FREE

PIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8 FREE

Functional reconstitution of the import of the yeast ADP/ATP carrier mediated by the TIM10 complex FREE

Propagation of the apoptotic signal by mitochondrial waves FREE

Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus FREE

Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads FREE

The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1 FREE

Regulation of BOB.1/OBF.1 stability by SIAH FREE

Integrity of the N-terminal transcription domain of p53 is required for mutant p53 interference with drug-induced apoptosis FREE

Polymerization of the SAM domain of TEL in leukemogenesis and transcriptional repression FREE

An essential nuclear envelope integral membrane protein, Brr6p, required for nuclear transport FREE

Regulation of alternative pre-mRNA splicing by the ERK MAP-kinase pathway FREE

Processing of 20S pre-rRNA to 18S ribosomal RNA in yeast requires Rrp10p, an essential non-ribosomal cytoplasmic protein FREE

The kink-turn: a new RNA secondary structure motif FREE

Non-canonical mechanism for translational control in bacteria: synthesis of ribosomal protein S1 FREE

Truncated initiation factor eIF4G lacking an eIF4E binding site can support capped mRNA translation FREE

Specific cleavage of hyper-edited dsRNAs FREE

Hda, a novel DnaA-related protein, regulates the replication cycle in Escherichia coli FREE

Stability, chromatin association and functional activity of mammalian pre-replication complex proteins during the cell cycle FREE

Excision of deaminated cytosine from the vertebrate genome: role of the SMUG1 uracil–DNA glycosylase FREE

Converting a DNA damage checkpoint effector (UmuD2C) into a lesion bypass polymerase (UmuD'2C) FREE

G-overhang dynamics at Tetrahymena telomeres FREE

dim-2 encodes a DNA methyltransferase responsible for all known cytosine methylation in Neurospora FREE

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Volume 20, Number 15
01 August 2001

Mycobacterium tuberculosis hemoglobin N displays a protein tunnel suited for O₂ diffusion to the heme FREE

Intracellular re-routing of prion protein prevents propagation of PrP^Sc and delays onset of prion disease FREE

Dephosphorylation of 2-syntrophin and Ca²⁺/-calpain-mediated cleavage of ICA512 upon stimulation of insulin secretion FREE

Converting a DNA damage checkpoint effector (UmuD₂C) into a lesion bypass polymerase (UmuD'₂C) FREE