Table of Contents

Volume 19, Number 16
15 August 2000
pp 4193-4422
Cover. Fluke of a Southern Right Whale. This photograph was taken by Freddy Frischknecht off the South African coast from a small research boat. Note the missing triangle that was most likely bitten out by a passing shark. Freddy joined whale researcher Peter Best for 2 weeks to help collect skin biopsies from the Southern Right. An article about this research has been published by Freddy in the Sueddeutsche Zeitung (4 July 2000). After being hunted to almost complete extinction, Southern Right Whales are increasing in numbers, unlike their cousin, the Northern Right Whale, which is the most endangered of whales. Freddy has just finished his PhD at EMBL in Heidelberg, Germany, working on the actin tail formation of vaccinia virus, and will move to a post-doctoral position at the Pasteur Institute in Paris. While the (actin-containing) tail of the pictured whale is a good 4 m wide, vaccinia actin tails are a bare 10
mlong.
Articles
Top of pageCrystal structure of mammalian poly(A) polymerase in complex with an analog of ATP FREE
The EMBO Journal (2000), 19, - 4193 - 4203, doi:10.1093/emboj/19.16.4193
The structure of L-amino acid oxidase reveals the substrate trajectory into an enantiomerically conserved active site FREE
The EMBO Journal (2000), 19, - 4204 - 4215, doi:10.1093/emboj/19.16.4204
The structure and function of the
2-adaptin appendage domain
FREE The EMBO Journal (2000), 19, - 4216 - 4227, doi:10.1093/emboj/19.16.4216
Crystal structure of the matrix protein VP40 from Ebola virus FREE
The EMBO Journal (2000), 19, - 4228 - 4236, doi:10.1093/emboj/19.16.4228
Redox signaling: globalization of gene expression FREE
The EMBO Journal (2000), 19, - 4237 - 4247, doi:10.1093/emboj/19.16.4237
ACAULIS5, an Arabidopsis gene required for stem elongation, encodes a spermine synthase FREE
The EMBO Journal (2000), 19, - 4248 - 4256, doi:10.1093/emboj/19.16.4248
Molecular targets of a human HNF1
mutation responsible for pancreatic
-cell dysfunction
FREE The EMBO Journal (2000), 19, - 4257 - 4264, doi:10.1093/emboj/19.16.4257
Dominant-negative activity of an
1B-adrenergic receptor signal-inactivating point mutation
FREE The EMBO Journal (2000), 19, - 4265 - 4271, doi:10.1093/emboj/19.16.4265
Dynamin mediates caveolar sequestration of muscarinic cholinergic receptors and alteration in NO signaling FREE
The EMBO Journal (2000), 19, - 4272 - 4280, doi:10.1093/emboj/19.16.4272
An intact SH3 domain is required for myosin I-induced actin polymerization FREE
The EMBO Journal (2000), 19, - 4281 - 4291, doi:10.1093/emboj/19.16.4281
The protein kinase PKR is required for p38 MAPK activation and the innate immune response to bacterial endotoxin FREE
The EMBO Journal (2000), 19, - 4292 - 4297, doi:10.1093/emboj/19.16.4292
Mechanism of regulation of the hypoxia-inducible factor-1
by the von Hippel-Lindau tumor suppressor protein
FREE The EMBO Journal (2000), 19, - 4298 - 4309, doi:10.1093/emboj/19.16.4298
Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90 FREE
The EMBO Journal (2000), 19, - 4310 - 4322, doi:10.1093/emboj/19.16.4310
Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis FREE
The EMBO Journal (2000), 19, - 4323 - 4331, doi:10.1093/emboj/19.16.4323
dMi-2 and ISWI chromatin remodelling factors have distinct nucleosome binding and mobilization properties FREE
The EMBO Journal (2000), 19, - 4332 - 4341, doi:10.1093/emboj/19.16.4332
Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3 FREE
The EMBO Journal (2000), 19, - 4342 - 4350, doi:10.1093/emboj/19.16.4342
Inhibition of S-phase progression by adeno-associated virus Rep78 protein is mediated by hypophosphorylated pRb FREE
The EMBO Journal (2000), 19, - 4351 - 4361, doi:10.1093/emboj/19.16.4351
Exportin 4: a mediator of a novel nuclear export pathway in higher eukaryotes FREE
The EMBO Journal (2000), 19, - 4362 - 4371, doi:10.1093/emboj/19.16.4362
The eukaryotic mRNA decapping protein Dcp1 interacts physically and functionally with the eIF4F translation initiation complex FREE
The EMBO Journal (2000), 19, - 4372 - 4382, doi:10.1093/emboj/19.16.4372
The ATPase cycle of Hsp90 drives a molecular 'clamp' via transient dimerization of the N-terminal domains FREE
The EMBO Journal (2000), 19, - 4383 - 4392, doi:10.1093/emboj/19.16.4383
Evaluating the oligomeric state of SecYEG in preprotein translocase FREE
The EMBO Journal (2000), 19, - 4393 - 4401, doi:10.1093/emboj/19.16.4393
Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2 FREE
The EMBO Journal (2000), 19, - 4402 - 4411, doi:10.1093/emboj/19.16.4402
Template definition by Tetrahymena telomerase reverse transcriptase FREE
The EMBO Journal (2000), 19, - 4412 - 4422, doi:10.1093/emboj/19.16.4412



