Close window
The EMBO Journal (2000) 19, 3990–4003, doi:10.1093/emboj/19.15.3990 Figure 11 Skin and hair follicle integrity is crucially dependent on 1 integrin expression on keratinocytes Cord Brakebusch, Richard Grose, Fabio Quondamatteo, Angel Ramirez, Jose L. Jorcano, Alison Pirro, Marcus Svensson, Rainer Herken, Takako Sasaki, Rupert Timpl, Sabine Werner and Reinhard Fässler

Figure 11 Defects in the esophagus of mutant mice. Esophagus sections of 2- (A–F) and 6-week-old (G and H) control (A, C, E and G) and mutant mice (B, D, F and H) were stained for lacZ activity (A and B), Ki67 (C and D), 4 integrin (E and F), and with hematoxylin–eosin (G and H). Basal cells in the mutant esophagus showed strong lacZ activity (B), reduced Ki67-positive proliferating cells (D) and a reduced staining for 4 integrin (F). In 6-week-old mice, mutant basal cells (H) displayed a different morphology than in normal mice (G). In addition, blisters were observed (H, arrow).

previous | next

Privacy policy	Copyright © 2000 by the European Molecular Biology Organization