Possible association of BLM in decreasing DNA double strand breaks during DNA replication

The EMBO Journal (2000) 19, 3428–3435, doi:10.1093/emboj/19.13.3428

Figure 5

Wensheng Wang, Masayuki Seki, Yoshiyasu Narita, Eiichiro Sonoda, Shunichi Takeda, Kouichi Yamada, Takashi Masuko, Toshiaki Katada and Takemi Enomoto

Figure 5
Histograms of SCE in wild-type, RAD54^-/-, BLM^-/- and BLM^-/-/RAD54^-/- cells. SCEs in the macrochromosomes were counted. Histograms show the frequency of cells with the indicated number of SCEs per cell. The mean number of SCEs per cell is shown in the upper right corner. (A) Wild-type cells; (B) BLM^-/- cells; (C) BLM^-/-/RAD54^-/- cells; (D) RAD54^-/- cells; (E) a superimposed figure of (A), (B), (C) and (D) expressed on the same scale.


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