Table of Contents

Volume 18, Number 8
15 April 1999

pp 2021-2310

• Articles

  Top of page

  • The crystal structure of a novel bacterial adenylyltransferase reveals half of sites reactivity FREE

    Tina Izard and Arie Geerlof

    The EMBO Journal (1999), 18, - 2021 - 2030, doi:10.1093/emboj/18.8.2021

    • Abstract - The crystal structure of a novel bacterial adenylyltransferase reveals half of sites reactivity
    • Full text
    • PDF (468 KB) - The crystal structure of a novel bacterial adenylyltransferase reveals half of sites reactivity

  • Crystal structure of baculovirus P35: role of a novel reactive site loop in apoptotic caspase inhibition FREE

    Andrew J. Fisher, Wilfred dela Cruz, Stephen J. Zoog, Christine L. Schneider and Paul D. Friesen

    The EMBO Journal (1999), 18, - 2031 - 2039, doi:10.1093/emboj/18.8.2031

    • Abstract - Crystal structure of baculovirus P35: role of a novel reactive site loop in apoptotic caspase inhibition
    • Full text
    • PDF (436 KB) - Crystal structure of baculovirus P35: role of a novel reactive site loop in apoptotic caspase inhibition

  • Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of Jurkat cells FREE

    Afshin Samali, Jiyang Cai, Boris Zhivotovsky, Dean P. Jones and Sten Orrenius

    The EMBO Journal (1999), 18, - 2040 - 2048, doi:10.1093/emboj/18.8.2040

    • Abstract - Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of Jurkat cells
    • Full text
    • PDF (334 KB) - Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of Jurkat cells

  • Hsp60 accelerates the maturation of pro-caspase-3 by upstream activator proteases during apoptosis FREE

    Steven Xanthoudakis, Sophie Roy, Dita Rasper, Trevor Hennessey, Yves Aubin, Robin Cassady, Paul Tawa, Rejean Ruel, Antony Rosen and Donald W. Nicholson

    The EMBO Journal (1999), 18, - 2049 - 2056, doi:10.1093/emboj/18.8.2049

    • Abstract - Hsp60 accelerates the maturation of pro-caspase-3 by upstream activator proteases during apoptosis
    • Full text
    • PDF (267 KB) - Hsp60 accelerates the maturation of pro-caspase-3 by upstream activator proteases during apoptosis

  • Flagellar protein localization mediated by a calcium–myristoyl/palmitoyl switch mechanism FREE

    Lisa M. Godsel and David M. Engman

    The EMBO Journal (1999), 18, - 2057 - 2065, doi:10.1093/emboj/18.8.2057

    • Abstract - Flagellar protein localization mediated by a calcium-myristoyl/palmitoyl switch mechanism
    • Full text
    • PDF (234 KB) - Flagellar protein localization mediated by a calcium-myristoyl/palmitoyl switch mechanism

  • AUX1 regulates root gravitropism in Arabidopsis by facilitating auxin uptake within root apical tissues FREE

    Alan Marchant, Joanna Kargul, Sean T. May, Philippe Muller, Alain Delbarre, Catherine Perrot-Rechenmann and Malcolm J. Bennett

    The EMBO Journal (1999), 18, - 2066 - 2073, doi:10.1093/emboj/18.8.2066

    • Abstract - AUX1 regulates root gravitropism in : Arabidopsis: by facilitating auxin uptake within root apical tissues
    • Full text
    • PDF (359 KB) - AUX1 regulates root gravitropism in : Arabidopsis: by facilitating auxin uptake within root apical tissues

  • Cytosolic ATPases, p97 and NSF, are sufficient to mediate rapid membrane fusion FREE

    Marlies Otter-Nilsson, Rob Hendriks, Eve-Isabelle Pecheur-Huet, Dick Hoekstra and Tommy Nilsson

    The EMBO Journal (1999), 18, - 2074 - 2083, doi:10.1093/emboj/18.8.2074

    • Abstract - Cytosolic ATPases, p97 and NSF, are sufficient to mediate rapid membrane fusion
    • Full text
    • PDF (295 KB) - Cytosolic ATPases, p97 and NSF, are sufficient to mediate rapid membrane fusion

  • Sequence determinants directing conversion of cysteine to formylglycine in eukaryotic sulfatases FREE

    Thomas Dierks, M.Rita Lecca, Petra Schlotterhose, Bernhard Schmidt and Kurt von Figura

    The EMBO Journal (1999), 18, - 2084 - 2091, doi:10.1093/emboj/18.8.2084

    • Abstract - Sequence determinants directing conversion of cysteine to formylglycine in eukaryotic sulfatases
    • Full text
    • PDF (405 KB) - Sequence determinants directing conversion of cysteine to formylglycine in eukaryotic sulfatases

  • Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium FREE

    Ruedi Meili, Charlene Ellsworth, Susan Lee, T.B.K. Reddy, Hui Ma and Richard A Firtel

    The EMBO Journal (1999), 18, - 2092 - 2105, doi:10.1093/emboj/18.8.2092

    • Abstract - Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in : Dictyostelium
    • Full text
    • PDF (739 KB) - Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in : Dictyostelium

  • The p16^INK4a tumour suppressor protein inhibits _v3 integrin-mediated cell spreading on vitronectin by blocking PKC-dependent localization of _v3 to focal contacts FREE

    Robin Fåhraeus and David P. Lane

    The EMBO Journal (1999), 18, - 2106 - 2118, doi:10.1093/emboj/18.8.2106

    • Abstract - The p16: INK4a: tumour suppressor protein inhibits [alpha]: v: [beta]: 3: integrin-mediated cell spreading on vitronectin by blocking PKC-dependent localization of [alpha]: v: [beta]: 3: to focal contacts
    • Full text
    • PDF (599 KB) - The p16: INK4a: tumour suppressor protein inhibits [alpha]: v: [beta]: 3: integrin-mediated cell spreading on vitronectin by blocking PKC-dependent localization of [alpha]: v: [beta]: 3: to focal contacts

  • A casein kinase I motif present in the cytoplasmic domain of members of the tumour necrosis factor ligand family is implicated in 'reverse signalling' FREE

    Alan D. Watts, Nicholas H. Hunt, Yewlan Wanigasekara, Garry Bloomfield, David Wallach, Basil D. Roufogalis and Geeta Chaudhri

    The EMBO Journal (1999), 18, - 2119 - 2126, doi:10.1093/emboj/18.8.2119

    • Abstract - A casein kinase I motif present in the cytoplasmic domain of members of the tumour necrosis factor ligand family is implicated in 'reverse signalling'
    • Full text
    • PDF (262 KB) - A casein kinase I motif present in the cytoplasmic domain of members of the tumour necrosis factor ligand family is implicated in 'reverse signalling'

  • Fetal liver development requires a paracrine action of oncostatin M through the gp130 signal transducer FREE

    Akihide Kamiya, Taisei Kinoshita, Yoshiaki Ito, Takaaki Matsui, Yoshihiro Morikawa, Emiko Senba, Kinichi Nakashima, Tetsuya Taga, Kanji Yoshida, Tadamitsu Kishimoto and Atsushi Miyajima

    The EMBO Journal (1999), 18, - 2127 - 2136, doi:10.1093/emboj/18.8.2127

    • Abstract - Fetal liver development requires a paracrine action of oncostatin M through the gp130 signal transducer
    • Full text
    • PDF (498 KB) - Fetal liver development requires a paracrine action of oncostatin M through the gp130 signal transducer

  • Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation FREE

    Clive S. Mason, Caroline J. Springer, Robert G Cooper, Giulio Superti-Furga, Christopher J. Marshall and Richard Marais

    The EMBO Journal (1999), 18, - 2137 - 2148, doi:10.1093/emboj/18.8.2137

    • Abstract - Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation
    • Full text
    • PDF (329 KB) - Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation

  • Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer FREE

    Peter M. Siegel, Eamonn D. Ryan, Robert D. Cardiff and William J. Muller

    The EMBO Journal (1999), 18, - 2149 - 2164, doi:10.1093/emboj/18.8.2149

    • Abstract - Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer
    • Full text
    • PDF (686 KB) - Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer

  • Surface densities of ephrin-B1 determine EphB1-coupled activation of cell attachment through _v3 and ₅₁ integrins FREE

    Uyen Huynh-Do, Elke Stein, Andy A. Lane, Hua Liu, Douglas P. Cerretti and Thomas O. Daniel

    The EMBO Journal (1999), 18, - 2165 - 2173, doi:10.1093/emboj/18.8.2165

    • Abstract - Surface densities of ephrin-B1 determine EphB1-coupled activation of cell attachment through [alpha]: v: [beta]: 3: and [alpha]: 5: [beta]: 1: integrins
    • Full text
    • PDF (277 KB) - Surface densities of ephrin-B1 determine EphB1-coupled activation of cell attachment through [alpha]: v: [beta]: 3: and [alpha]: 5: [beta]: 1: integrins

  • Maintenance of G₂ arrest in the Xenopus oocyte: a role for 14-3-3-mediated inhibition of Cdc25 nuclear import FREE

    Jing Yang, Katharine Winkler, Minoru Yoshida and Sally Kornbluth

    The EMBO Journal (1999), 18, - 2174 - 2183, doi:10.1093/emboj/18.8.2174

    • Abstract - Maintenance of G: 2: arrest in the : Xenopus: oocyte: a role for 14-3-3-mediated inhibition of Cdc25 nuclear import
    • Full text
    • PDF (355 KB) - Maintenance of G: 2: arrest in the : Xenopus: oocyte: a role for 14-3-3-mediated inhibition of Cdc25 nuclear import

  • The disappearance of cyclin B at the end of mitosis is regulated spatially in Drosophila cells FREE

    Jun-yong Huang and Jordan W. Raff

    The EMBO Journal (1999), 18, - 2184 - 2195, doi:10.1093/emboj/18.8.2184

    • Abstract - The disappearance of cyclin B at the end of mitosis is regulated spatially in : Drosophila: cells
    • Full text
    • PDF (455 KB) - The disappearance of cyclin B at the end of mitosis is regulated spatially in : Drosophila: cells

  • Hes1 and Hes5 as Notch effectors in mammalian neuronal differentiation FREE

    Toshiyuki Ohtsuka, Makoto Ishibashi, Gérald Gradwohl, Shigetada Nakanishi, François Guillemot and Ryoichiro Kageyama

    The EMBO Journal (1999), 18, - 2196 - 2207, doi:10.1093/emboj/18.8.2196

    • Abstract - Hes1: and : Hes5: as Notch effectors in mammalian neuronal differentiation
    • Full text
    • PDF (870 KB) - Hes1: and : Hes5: as Notch effectors in mammalian neuronal differentiation

  • The C-terminal domain of Armadillo binds to hypophosphorylated Teashirt to modulate Wingless signalling in Drosophila FREE

    Armel Gallet, Corinne Angelats, Alfrun Erkner, Bernard Charroux, Laurent Fasano and Stephen Kerridge

    The EMBO Journal (1999), 18, - 2208 - 2217, doi:10.1093/emboj/18.8.2208

    • Abstract - The C-terminal domain of Armadillo binds to hypophosphorylated Teashirt to modulate Wingless signalling in : Drosophila
    • Full text
    • PDF (389 KB) - The C-terminal domain of Armadillo binds to hypophosphorylated Teashirt to modulate Wingless signalling in : Drosophila

  • A 3'-flanking NF-B site mediates developmental silencing of the human -globin gene FREE

    Zhibin Wang and Stephen A. Liebhaber

    The EMBO Journal (1999), 18, - 2218 - 2228, doi:10.1093/emboj/18.8.2218

    • Abstract - A 3[prime]-flanking NF-[kappa]B site mediates developmental silencing of the human [zeta]-globin gene
    • Full text
    • PDF (337 KB) - A 3[prime]-flanking NF-[kappa]B site mediates developmental silencing of the human [zeta]-globin gene

  • Role of the essential yeast protein PSU1 in transcriptional enhancement by the ligand-dependent activation function AF-2 of nuclear receptors FREE

    Claudine Gaudon, Pierre Chambon and Régine Losson

    The EMBO Journal (1999), 18, - 2229 - 2240, doi:10.1093/emboj/18.8.2229

    • Abstract - Role of the essential yeast protein PSU1 in transcriptional enhancement by the ligand-dependent activation function AF-2 of nuclear receptors
    • Full text
    • PDF (619 KB) - Role of the essential yeast protein PSU1 in transcriptional enhancement by the ligand-dependent activation function AF-2 of nuclear receptors

  • Regional specialization in human nuclei: visualization of discrete sites of transcription by RNA polymerase III FREE

    Ana Pombo, Dean A. Jackson, Michael Hollinshead, Zhengxin Wang, Robert G. Roeder and Peter R. Cook

    The EMBO Journal (1999), 18, - 2241 - 2253, doi:10.1093/emboj/18.8.2241

    • Abstract - Regional specialization in human nuclei: visualization of discrete sites of transcription by RNA polymerase III
    • Full text
    • PDF (484 KB) - Regional specialization in human nuclei: visualization of discrete sites of transcription by RNA polymerase III

  • Continuous and widespread roles for the Swi–Snf complex in transcription FREE

    Stephen R. Biggar and Gerald R. Crabtree

    The EMBO Journal (1999), 18, - 2254 - 2264, doi:10.1093/emboj/18.8.2254

    • Abstract - Continuous and widespread roles for the Swi-Snf complex in transcription
    • Full text
    • PDF (324 KB) - Continuous and widespread roles for the Swi-Snf complex in transcription

  • Trypanosoma brucei variant surface glycoprotein regulation involves coupled activation/inactivation and chromatin remodeling of expression sites FREE

    Miguel Navarro, George A.M. Cross and Elizabeth Wirtz

    The EMBO Journal (1999), 18, - 2265 - 2272, doi:10.1093/emboj/18.8.2265

    • Abstract - Trypanosoma brucei: variant surface glycoprotein regulation involves coupled activation/inactivation and chromatin remodeling of expression sites
    • Full text
    • PDF (224 KB) - Trypanosoma brucei: variant surface glycoprotein regulation involves coupled activation/inactivation and chromatin remodeling of expression sites

  • Influenza A virus NS1 protein targetspoly(A)-binding protein II of the cellular 3'-end processing machinery FREE

    Zhongying Chen, Yongzhong Li and Robert M. Krug

    The EMBO Journal (1999), 18, - 2273 - 2283, doi:10.1093/emboj/18.8.2273

    • Abstract - Influenza A virus NS1 protein targetspoly(A)-binding protein II of the cellular 3[prime]-end processing machinery
    • Full text
    • PDF (314 KB) - Influenza A virus NS1 protein targetspoly(A)-binding protein II of the cellular 3[prime]-end processing machinery

  • Dynamics and efficiency in vivo of UGA-directed selenocysteine insertion at the ribosome FREE

    Sabine Suppmann, Britt C. Persson and August Böck

    The EMBO Journal (1999), 18, - 2284 - 2293, doi:10.1093/emboj/18.8.2284

    • Abstract - Dynamics and efficiency : in vivo: of UGA-directed selenocysteine insertion at the ribosome
    • Full text
    • PDF (237 KB) - Dynamics and efficiency : in vivo: of UGA-directed selenocysteine insertion at the ribosome

  • Cytoplasmic polyadenylation elements mediate masking and unmasking of cyclin B1 mRNA FREE

    Cornelia H. de Moor and Joel D. Richter

    The EMBO Journal (1999), 18, - 2294 - 2303, doi:10.1093/emboj/18.8.2294

    • Abstract - Cytoplasmic polyadenylation elements mediate masking and unmasking of cyclin B1 mRNA
    • Full text
    • PDF (361 KB) - Cytoplasmic polyadenylation elements mediate masking and unmasking of cyclin B1 mRNA

  • Binding of SeqA protein to DNA requires interaction between two or more complexes bound to separate hemimethylated GATC sequences FREE

    Therese Brendler and Stuart Austin

    The EMBO Journal (1999), 18, - 2304 - 2310, doi:10.1093/emboj/18.8.2304

    • Abstract - Binding of SeqA protein to DNA requires interaction between two or more complexes bound to separate hemimethylated GATC sequences
    • Full text
    • PDF (242 KB) - Binding of SeqA protein to DNA requires interaction between two or more complexes bound to separate hemimethylated GATC sequences

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