Figure 2
A region of the Yersinia pseudotuberculosis invasin protein enhances integrin-mediated uptake into mammalian cells and promotes self-association
Petra Dersch and Ralph R. Isberg
- The EMBO Journal (1999) 18, 1199 - 1213
- doi:10.1093/emboj/18.5.1199
Binding and entry efficiency of latex beads coated with different invasin derivatives. A total of 5
106 beads coated with Inv197 (
) and Inv497 (
) as described (Materials and methods) were used to challenge HEp-2 cells, and surface-bound beads were visualized by immunofluorescence microscopy. The total number of cell-associated beads was visualized and counted microscopically with phase contrast (A) and the percentage of adherent beads internalized per cell is shown in (B).
