Table of Contents

Volume 18, Number 24
15 December 1999

pp 6867-7085

• New EMBO Members Review

  Top of page

  • Wnt signaling and the activation of myogenesis in mammals FREE

    Giulio Cossu and Ugo Borello

    The EMBO Journal (1999), 18, - 6867 - 6872, doi:10.1093/emboj/18.24.6867

    • Abstract - Wnt signaling and the activation of myogenesis in mammals
    • Full text
    • PDF (228 KB) - Wnt signaling and the activation of myogenesis in mammals

  • Planar polarity in the Drosophila eye: a multifaceted view of signaling specificity and cross-talk FREE

    Marek Mlodzik

    The EMBO Journal (1999), 18, - 6873 - 6879, doi:10.1093/emboj/18.24.6873

    • Abstract - Planar polarity in the : Drosophila: eye: a multifaceted view of signaling specificity and cross-talk
    • Full text
    • PDF (693 KB) - Planar polarity in the : Drosophila: eye: a multifaceted view of signaling specificity and cross-talk

• Articles

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  • Crystal structure of calpain reveals the structural basis for Ca²⁺-dependent protease activity and a novel mode of enzyme activation FREE

    Christopher M. Hosfield, John S. Elce, Peter L. Davies and Zongchao Jia

    The EMBO Journal (1999), 18, - 6880 - 6889, doi:10.1093/emboj/18.24.6880

    • Abstract - Crystal structure of calpain reveals the structural basis for Ca: 2+: -dependent protease activity and a novel mode of enzyme activation
    • Full text
    • PDF (1,132 KB) - Crystal structure of calpain reveals the structural basis for Ca: 2+: -dependent protease activity and a novel mode of enzyme activation

  • Crystal structure of the ARF-GAP domain and ankyrin repeats of PYK2-associated protein FREE

    Valsan Mandiyan, Julian Andreev, Joseph Schlessinger and Stevan R. Hubbard

    The EMBO Journal (1999), 18, - 6890 - 6898, doi:10.1093/emboj/18.24.6890

    • Abstract - Crystal structure of the ARF-GAP domain and ankyrin repeats of PYK2-associated protein [beta]
    • Full text
    • PDF (1,444 KB) - Crystal structure of the ARF-GAP domain and ankyrin repeats of PYK2-associated protein [beta]

  • Crystal structure of UvrB, a DNA helicase adapted for nucleotide excision repair FREE

    Karsten Theis, Paul J. Chen, Milan Skorvaga, Bennett Van Houten and Caroline Kisker

    The EMBO Journal (1999), 18, - 6899 - 6907, doi:10.1093/emboj/18.24.6899

    • Abstract - Crystal structure of UvrB, a DNA helicase adapted for nucleotide excision repair
    • Full text
    • PDF (794 KB) - Crystal structure of UvrB, a DNA helicase adapted for nucleotide excision repair

  • The monomeric homing endonuclease PI-SceI has two catalytic centres for cleavage of the two strands of its DNA substrate FREE

    Frauke Christ, Sylvia Schoettler, Wolfgang Wende, Shawn Steuer, Alfred Pingoud and Vera Pingoud

    The EMBO Journal (1999), 18, - 6908 - 6916, doi:10.1093/emboj/18.24.6908

    • Abstract - The monomeric homing endonuclease PI-: Sce: I has two catalytic centres for cleavage of the two strands of its DNA substrate
    • Full text
    • PDF (430 KB) - The monomeric homing endonuclease PI-: Sce: I has two catalytic centres for cleavage of the two strands of its DNA substrate

  • Functionally different GPI proteins are organized in different domains on the neuronal surface FREE

    Nathalie Madore, Karen L. Smith, Catriona H. Graham, Angela Jen, Ken Brady, Susan Hall and Roger Morris

    The EMBO Journal (1999), 18, - 6917 - 6926, doi:10.1093/emboj/18.24.6917

    • Abstract - Functionally different GPI proteins are organized in different domains on the neuronal surface
    • Full text
    • PDF (1,342 KB) - Functionally different GPI proteins are organized in different domains on the neuronal surface

  • Effects of macromolecular crowding on protein folding and aggregation FREE

    Bert van den Berg, R.John Ellis and Christopher M. Dobson

    The EMBO Journal (1999), 18, - 6927 - 6933, doi:10.1093/emboj/18.24.6927

    • Abstract - Effects of macromolecular crowding on protein folding and aggregation
    • Full text
    • PDF (111 KB) - Effects of macromolecular crowding on protein folding and aggregation

  • Identification of thermolabile Escherichia coli proteins: prevention and reversion of aggregation by DnaK and ClpB FREE

    Axel Mogk, Toshifumi Tomoyasu, Pierre Goloubinoff, Stefan Rüdiger, Daniel Röder, Hanno Langen and Bernd Bukau

    The EMBO Journal (1999), 18, - 6934 - 6949, doi:10.1093/emboj/18.24.6934

    • Abstract - Identification of thermolabile : Escherichia coli: proteins: prevention and reversion of aggregation by DnaK and ClpB
    • Full text
    • PDF (1,203 KB) - Identification of thermolabile : Escherichia coli: proteins: prevention and reversion of aggregation by DnaK and ClpB

  • Recruitment of the protein tyrosine phosphatase CSW by DOS is an essential step during signaling by the Sevenless receptor tyrosine kinase FREE

    Ronald Herbst, Xiaolong Zhang, Jun Qin and Michael A. Simon

    The EMBO Journal (1999), 18, - 6950 - 6961, doi:10.1093/emboj/18.24.6950

    • Abstract - Recruitment of the protein tyrosine phosphatase CSW by DOS is an essential step during signaling by the Sevenless receptor tyrosine kinase
    • Full text
    • PDF (1,370 KB) - Recruitment of the protein tyrosine phosphatase CSW by DOS is an essential step during signaling by the Sevenless receptor tyrosine kinase

  • Ectodomain shedding of TGF- and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades FREE

    Huizhou Fan and Rik Derynck

    The EMBO Journal (1999), 18, - 6962 - 6972, doi:10.1093/emboj/18.24.6962

    • Abstract - Ectodomain shedding of TGF-[alpha] and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades
    • Full text
    • PDF (548 KB) - Ectodomain shedding of TGF-[alpha] and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades

  • Cell type-specific activation of mitogen-activated protein kinases by CpG-DNA controls interleukin-12 release from antigen-presenting cells FREE

    Hans Häcker, Harald Mischak, Georg Häcker, Sema Eser, Norbert Prenzel, Axel Ullrich and Hermann Wagner

    The EMBO Journal (1999), 18, - 6973 - 6982, doi:10.1093/emboj/18.24.6973

    • Abstract - Cell type-specific activation of mitogen-activated protein kinases by CpG-DNA controls interleukin-12 release from antigen-presenting cells
    • Full text
    • PDF (359 KB) - Cell type-specific activation of mitogen-activated protein kinases by CpG-DNA controls interleukin-12 release from antigen-presenting cells

  • Direct inhibition of G₁ cdk kinase activity by MyoD promotes myoblast cell cycle withdrawal and terminal differentiation FREE

    Jian-Min Zhang, Xiaohang Zhao, Qin Wei and Bruce M. Paterson

    The EMBO Journal (1999), 18, - 6983 - 6993, doi:10.1093/emboj/18.24.6983

    • Abstract - Direct inhibition of G: 1: cdk kinase activity by MyoD promotes myoblast cell cycle withdrawal and terminal differentiation
    • Full text
    • PDF (759 KB) - Direct inhibition of G: 1: cdk kinase activity by MyoD promotes myoblast cell cycle withdrawal and terminal differentiation

  • Interaction between developmental and cell cycle regulators is required for morphogenesis in Aspergillus nidulans FREE

    Xiang S. Ye, Sheau-Ling Lee, Tom D. Wolkow, Sarah-Lee McGuire, John E. Hamer, G.Craig Wood and Stephen A. Osmani

    The EMBO Journal (1999), 18, - 6994 - 7001, doi:10.1093/emboj/18.24.6994

    • Abstract - Interaction between developmental and cell cycle regulators is required for morphogenesis in : Aspergillus nidulans
    • Full text
    • PDF (459 KB) - Interaction between developmental and cell cycle regulators is required for morphogenesis in : Aspergillus nidulans

  • Serine 15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2 FREE

    Nicolas Dumaz and David W. Meek

    The EMBO Journal (1999), 18, - 7002 - 7010, doi:10.1093/emboj/18.24.7002

    • Abstract - Serine 15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2
    • Full text
    • PDF (430 KB) - Serine 15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2

  • RAR-independent RXR signaling induces t(15;17) leukemia cell maturation FREE

    Gérard Benoit, Lucia Altucci, Maria Flexor, Sandrine Ruchaud, Johan Lillehaug, Wolfgang Raffelsberger, Hinrich Gronemeyer and Michel Lanotte

    The EMBO Journal (1999), 18, - 7011 - 7018, doi:10.1093/emboj/18.24.7011

    • Abstract - RAR-independent RXR signaling induces t(15;17) leukemia cell maturation
    • Full text
    • PDF (811 KB) - RAR-independent RXR signaling induces t(15;17) leukemia cell maturation

  • Mga, a dual-specificity transcription factor that interacts with Max and contains a T-domain DNA-binding motif FREE

    Peter J. Hurlin, Eirìkur Steingrìmsson, Neal G. Copeland, Nancy A. Jenkins and Robert N. Eisenman

    The EMBO Journal (1999), 18, - 7019 - 7028, doi:10.1093/emboj/18.24.7019

    • Abstract - Mga, a dual-specificity transcription factor that interacts with Max and contains a T-domain DNA-binding motif
    • Full text
    • PDF (743 KB) - Mga, a dual-specificity transcription factor that interacts with Max and contains a T-domain DNA-binding motif

  • Osa associates with the Brahma chromatin remodeling complex and promotes the activation of some target genes FREE

    Russell T. Collins, Takako Furukawa, Naoko Tanese and Jessica E. Treisman

    The EMBO Journal (1999), 18, - 7029 - 7040, doi:10.1093/emboj/18.24.7029

    • Abstract - Osa associates with the Brahma chromatin remodeling complex and promotes the activation of some target genes
    • Full text
    • PDF (1,161 KB) - Osa associates with the Brahma chromatin remodeling complex and promotes the activation of some target genes

  • SIR repression of a yeast heat shock gene: UAS and TATA footprints persist within heterochromatin FREE

    Edward A. Sekinger and David S. Gross

    The EMBO Journal (1999), 18, - 7041 - 7055, doi:10.1093/emboj/18.24.7041

    • Abstract - SIR: repression of a yeast heat shock gene: UAS and TATA footprints persist within heterochromatin
    • Full text
    • PDF (1,137 KB) - SIR: repression of a yeast heat shock gene: UAS and TATA footprints persist within heterochromatin

  • C to U editing of the anticodon of imported mitochondrial tRNA^Trp allows decoding of the UGA stop codon in Leishmania tarentolae FREE

    Juan D. Alfonzo, Valerie Blanc, Antonio M. Estévez, Mary Anne T. Rubio and Larry Simpson

    The EMBO Journal (1999), 18, - 7056 - 7062, doi:10.1093/emboj/18.24.7056

    • Abstract - C to U editing of the anticodon of imported mitochondrial tRNA: Trp: allows decoding of the UGA stop codon in : Leishmania tarentolae
    • Full text
    • PDF (348 KB) - C to U editing of the anticodon of imported mitochondrial tRNA: Trp: allows decoding of the UGA stop codon in : Leishmania tarentolae

  • The Escherichia coli trmE (mnmE) gene, involved in tRNA modification, codes for an evolutionarily conserved GTPase with unusual biochemical properties FREE

    Hugo Cabedo, Fernando Macián, Magda Villarroya, Juan C. Escudero, Marta Martínez-Vicente, Erwin Knecht and M. Eugenia Armengod

    The EMBO Journal (1999), 18, - 7063 - 7076, doi:10.1093/emboj/18.24.7063

    • Abstract - The : Escherichia coli trmE: (: mnmE: ) gene, involved in tRNA modification, codes for an evolutionarily conserved GTPase with unusual biochemical properties
    • Full text
    • PDF (394 KB) - The : Escherichia coli trmE: (: mnmE: ) gene, involved in tRNA modification, codes for an evolutionarily conserved GTPase with unusual biochemical properties

  • Aphid transmission of cauliflower mosaic virus requires the viral PIII protein FREE

    Véronique Leh, Emmanuel Jacquot, Angèle Geldreich, Thomas Hermann, Denis Leclerc, Martine Cerutti, Pierre Yot, Mario Keller and Stéphane Blanc

    The EMBO Journal (1999), 18, - 7077 - 7085, doi:10.1093/emboj/18.24.7077

    • Abstract - Aphid transmission of cauliflower mosaic virus requires the viral PIII protein
    • Full text
    • PDF (873 KB) - Aphid transmission of cauliflower mosaic virus requires the viral PIII protein

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