Figure 3
Planar polarity in the Drosophila eye: a multifaceted view of signaling specificity and cross-talk
Marek Mlodzik
- The EMBO Journal (1999) 18, 6873 - 6879
- doi:10.1093/emboj/18.24.6873
The planar polarity signaling cascade. Schematic presentation of the information flow and its comparison with canonical Wnt signaling (in gray) is shown. The two pathways split (probably) at the level of Dsh. Different domains within Dsh are responsible for the specific activation of the two pathways. In the embryo, however, both Fz and Fz2 are activated by Wg and signal through the Armadillo/
-catenin/Wnt pathway.
