Table of Contents

Volume 18, Number 23
01 December 1999

pp 6585-6864

• New EMBO Members Review

  Top of page

  • Light and dark in chromatin repair: repair of UV-induced DNA lesions by photolyase and nucleotide excision repair FREE

    Fritz Thoma

    The EMBO Journal (1999), 18, - 6585 - 6598, doi:10.1093/emboj/18.23.6585

    • Abstract - Light and dark in chromatin repair: repair of UV-induced DNA lesions by photolyase and nucleotide excision repair
    • Full text
    • PDF (469 KB) - Light and dark in chromatin repair: repair of UV-induced DNA lesions by photolyase and nucleotide excision repair

• Articles

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  • Crystal structure of a thwarted mismatch glycosylase DNA repair complex FREE

    Tracey E. Barrett, Orlando D. Schärer, Renos Savva, Tom Brown, Josef Jiricny, Gregory L. Verdine and Laurence H. Pearl

    The EMBO Journal (1999), 18, - 6599 - 6609, doi:10.1093/emboj/18.23.6599

    • Abstract - Crystal structure of a thwarted mismatch glycosylase DNA repair complex
    • Full text
    • PDF (1,765 KB) - Crystal structure of a thwarted mismatch glycosylase DNA repair complex

  • The structure of a chromosomal high mobility group protein–DNA complex reveals sequence-neutral mechanisms important for non-sequence-specific DNA recognition FREE

    Frank V. Murphy IV, Robert M. Sweet and Mair E.A. Churchill

    The EMBO Journal (1999), 18, - 6610 - 6618, doi:10.1093/emboj/18.23.6610

    • Abstract - The structure of a chromosomal high mobility group protein-DNA complex reveals sequence-neutral mechanisms important for non-sequence-specific DNA recognition
    • Full text
    • PDF (819 KB) - The structure of a chromosomal high mobility group protein-DNA complex reveals sequence-neutral mechanisms important for non-sequence-specific DNA recognition

  • Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells FREE

    Yuko Yamaguchi-Iwai, Eiichiro Sonoda, Masao S. Sasaki, Ciaran Morrison, Tokuko Haraguchi, Yasushi Hiraoka, Yukiko M. Yamashita, Takashi Yagi, Minoru Takata, Carolyn Price, Naoki Kakazu and Shunichi Takeda

    The EMBO Journal (1999), 18, - 6619 - 6629, doi:10.1093/emboj/18.23.6619

    • Abstract - Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells
    • Full text
    • PDF (553 KB) - Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells

  • Quantitative comparison of DNA looping in vitro and in vivo: chromatin increases effective DNA flexibility at short distances FREE

    Leonie Ringrose, Sophie Chabanis, Pierre-Olivier Angrand, Catherine Woodroofe and A.Francis Stewart

    The EMBO Journal (1999), 18, - 6630 - 6641, doi:10.1093/emboj/18.23.6630

    • Abstract - Quantitative comparison of DNA looping : in vitro: and : in vivo: : chromatin increases effective DNA flexibility at short distances
    • Full text
    • PDF (685 KB) - Quantitative comparison of DNA looping : in vitro: and : in vivo: : chromatin increases effective DNA flexibility at short distances

  • Replication cycle-coordinated change of the adenine nucleotide-bound forms of DnaA protein in Escherichia coli FREE

    Kenji Kurokawa, Satoshi Nishida, Akiko Emoto, Kazuhisa Sekimizu and Tsutomu Katayama

    The EMBO Journal (1999), 18, - 6642 - 6652, doi:10.1093/emboj/18.23.6642

    • Abstract - Replication cycle-coordinated change of the adenine nucleotide-bound forms of DnaA protein in : Escherichia coli
    • Full text
    • PDF (372 KB) - Replication cycle-coordinated change of the adenine nucleotide-bound forms of DnaA protein in : Escherichia coli

  • Solution structure of the methyl-CpG-binding domain of the methylation-dependent transcriptional repressor MBD1 FREE

    Izuru Ohki, Nobuya Shimotake, Naoyuki Fujita, Mitsuyoshi Nakao and Masahiro Shirakawa

    The EMBO Journal (1999), 18, - 6653 - 6661, doi:10.1093/emboj/18.23.6653

    • Abstract - Solution structure of the methyl-CpG-binding domain of the methylation-dependent transcriptional repressor MBD1
    • Full text
    • PDF (971 KB) - Solution structure of the methyl-CpG-binding domain of the methylation-dependent transcriptional repressor MBD1

  • A new regulatory domain on the TATA-binding protein FREE

    Yong Cang, David T. Auble and Gregory Prelich

    The EMBO Journal (1999), 18, - 6662 - 6671, doi:10.1093/emboj/18.23.6662

    • Abstract - A new regulatory domain on the TATA-binding protein
    • Full text
    • PDF (683 KB) - A new regulatory domain on the TATA-binding protein

  • Gal83 mediates the interaction of the Snf1 kinase complex with the transcription activator Sip4 FREE

    Olivier Vincent and Marian Carlson

    The EMBO Journal (1999), 18, - 6672 - 6681, doi:10.1093/emboj/18.23.6672

    • Abstract - Gal83 mediates the interaction of the Snf1 kinase complex with the transcription activator Sip4
    • Full text
    • PDF (381 KB) - Gal83 mediates the interaction of the Snf1 kinase complex with the transcription activator Sip4

  • An N-terminal nuclear export signal is required for the nucleocytoplasmic shuttling of IB FREE

    Connie Johnson, Daniel Van Antwerp and Thomas J. Hope

    The EMBO Journal (1999), 18, - 6682 - 6693, doi:10.1093/emboj/18.23.6682

    • Abstract - An N-terminal nuclear export signal is required for the nucleocytoplasmic shuttling of I[kappa]B[alpha]
    • Full text
    • PDF (1,097 KB) - An N-terminal nuclear export signal is required for the nucleocytoplasmic shuttling of I[kappa]B[alpha]

  • NF-B activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase FREE

    Joel L. Pomerantz and David Baltimore

    The EMBO Journal (1999), 18, - 6694 - 6704, doi:10.1093/emboj/18.23.6694

    • Abstract - NF-[kappa]B activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase
    • Full text
    • PDF (551 KB) - NF-[kappa]B activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase

  • Kinetic dissection of fundamental processes of eukaryotic translation initiation in vitro FREE

    Jon R. Lorsch and Daniel Herschlag

    The EMBO Journal (1999), 18, - 6705 - 6717, doi:10.1093/emboj/18.23.6705

    • Abstract - Kinetic dissection of fundamental processes of eukaryotic translation initiation : in vitro
    • Full text
    • PDF (282 KB) - Kinetic dissection of fundamental processes of eukaryotic translation initiation : in vitro

  • Calreticulin functions in vitro as a molecular chaperone for both glycosylated and non-glycosylated proteins FREE

    Yoshiro Saito, Yoshito Ihara, Michael R. Leach, Myrna F. Cohen-Doyle and David B. Williams

    The EMBO Journal (1999), 18, - 6718 - 6729, doi:10.1093/emboj/18.23.6718

    • Abstract - Calreticulin functions : in vitro: as a molecular chaperone for both glycosylated and non-glycosylated proteins
    • Full text
    • PDF (577 KB) - Calreticulin functions : in vitro: as a molecular chaperone for both glycosylated and non-glycosylated proteins

  • MtGimC, a novel archaeal chaperone related to the eukaryotic chaperonin cofactor GimC/prefoldin FREE

    Michel R. Leroux, Marcus Fändrich, Daniel Klunker, Katja Siegers, Andrei N. Lupas, James R. Brown, Elmar Schiebel, Christopher M. Dobson and F.Ulrich Hartl

    The EMBO Journal (1999), 18, - 6730 - 6743, doi:10.1093/emboj/18.23.6730

    • Abstract - MtGimC, a novel archaeal chaperone related to the eukaryotic chaperonin cofactor GimC/prefoldin
    • Full text
    • PDF (1,032 KB) - MtGimC, a novel archaeal chaperone related to the eukaryotic chaperonin cofactor GimC/prefoldin

  • Hsp26: a temperature-regulated chaperone FREE

    Martin Haslbeck, Stefan Walke, Thusnelda Stromer, Monika Ehrnsperger, Helen E. White, Shaoxia Chen, Helen R. Saibil and Johannes Buchner

    The EMBO Journal (1999), 18, - 6744 - 6751, doi:10.1093/emboj/18.23.6744

    • Abstract - Hsp26: a temperature-regulated chaperone
    • Full text
    • PDF (545 KB) - Hsp26: a temperature-regulated chaperone

  • Two activities of cofilin, severing and accelerating directional depolymerization of actin filaments, are affected differentially by mutations around the actin-binding helix FREE

    Kenji Moriyama and Ichiro Yahara

    The EMBO Journal (1999), 18, - 6752 - 6761, doi:10.1093/emboj/18.23.6752

    • Abstract - Two activities of cofilin, severing and accelerating directional depolymerization of actin filaments, are affected differentially by mutations around the actin-binding helix
    • Full text
    • PDF (607 KB) - Two activities of cofilin, severing and accelerating directional depolymerization of actin filaments, are affected differentially by mutations around the actin-binding helix

  • Interaction of agrin with laminin requires a coiled-coil conformation of the agrin-binding site within the laminin 1 chain FREE

    Richard A. Kammerer, Therese Schulthess, Ruth Landwehr, Beat Schumacher, Ariel Lustig, Peter D. Yurchenco, Markus A. Ruegg, Jürgen Engel and Alain J. Denzer

    The EMBO Journal (1999), 18, - 6762 - 6770, doi:10.1093/emboj/18.23.6762

    • Abstract - Interaction of agrin with laminin requires a coiled-coil conformation of the agrin-binding site within the laminin [gamma]1 chain
    • Full text
    • PDF (378 KB) - Interaction of agrin with laminin requires a coiled-coil conformation of the agrin-binding site within the laminin [gamma]1 chain

  • Host cyclophilin A mediates HIV-1 attachment to target cells via heparans FREE

    Andrew C.S. Saphire, Michael D. Bobardt and Philippe A. Gallay

    The EMBO Journal (1999), 18, - 6771 - 6785, doi:10.1093/emboj/18.23.6771

    • Abstract - Host cyclophilin A mediates HIV-1 attachment to target cells via heparans
    • Full text
    • PDF (349 KB) - Host cyclophilin A mediates HIV-1 attachment to target cells via heparans

  • Dynein motor regulation stabilizes interphase microtubule arrays and determines centrosome position FREE

    Michael P. Koonce, Jana Köhler, Ralph Neujahr, Jean-Marc Schwartz, Irina Tikhonenko and Günther Gerisch

    The EMBO Journal (1999), 18, - 6786 - 6792, doi:10.1093/emboj/18.23.6786

    • Abstract - Dynein motor regulation stabilizes interphase microtubule arrays and determines centrosome position
    • Full text
    • PDF (769 KB) - Dynein motor regulation stabilizes interphase microtubule arrays and determines centrosome position

  • Yersinia enterocolitica type III secretion–translocationsystem: channel formation by secreted Yops FREE

    Florence Tardy, Fabrice Homblé, Cécile Neyt, Ruddy Wattiez, Guy R. Cornelis, Jean-Marie Ruysschaert and Véronique Cabiaux

    The EMBO Journal (1999), 18, - 6793 - 6799, doi:10.1093/emboj/18.23.6793

    • Abstract - Yersinia enterocolitica: type III secretion-translocationsystem: channel formation by secreted Yops
    • Full text
    • PDF (216 KB) - Yersinia enterocolitica: type III secretion-translocationsystem: channel formation by secreted Yops

  • Cysteine-scanning mutagenesis provides no evidence for the extracellular accessibility of the nucleotide-binding domains of the multidrug resistance transporter P-glycoprotein FREE

    Emma J. Blott, Christopher F. Higgins and Kenneth J. Linton

    The EMBO Journal (1999), 18, - 6800 - 6808, doi:10.1093/emboj/18.23.6800

    • Abstract - Cysteine-scanning mutagenesis provides no evidence for the extracellular accessibility of the nucleotide-binding domains of the multidrug resistance transporter P-glycoprotein
    • Full text
    • PDF (713 KB) - Cysteine-scanning mutagenesis provides no evidence for the extracellular accessibility of the nucleotide-binding domains of the multidrug resistance transporter P-glycoprotein

  • Redox signalling in the chloroplast: structure of oxidized pea fructose-1,6-bisphosphate phosphatase FREE

    Mohammed Chiadmi, Alda Navaza, Myroslawa Miginiac-Maslow, Jean-Pierre Jacquot and Jacqueline Cherfils

    The EMBO Journal (1999), 18, - 6809 - 6815, doi:10.1093/emboj/18.23.6809

    • Abstract - Redox signalling in the chloroplast: structure of oxidized pea fructose-1,6-bisphosphate phosphatase
    • Full text
    • PDF (682 KB) - Redox signalling in the chloroplast: structure of oxidized pea fructose-1,6-bisphosphate phosphatase

  • Carbohydrate deficient glycoprotein syndrome type IV: deficiency of dolichyl-P-Man:Man₅ GlcNAc₂-PP-dolichyl mannosyltransferase FREE

    Christian Körner, Roland Knauer, Ulrich Stephani, Thorsten Marquardt, Ludwig Lehle and Kurt von Figura

    The EMBO Journal (1999), 18, - 6816 - 6822, doi:10.1093/emboj/18.23.6816

    • Abstract - Carbohydrate deficient glycoprotein syndrome type IV: deficiency of dolichyl-P-Man:Man: 5: GlcNAc: 2: -PP-dolichyl mannosyltransferase
    • Full text
    • PDF (402 KB) - Carbohydrate deficient glycoprotein syndrome type IV: deficiency of dolichyl-P-Man:Man: 5: GlcNAc: 2: -PP-dolichyl mannosyltransferase

  • Crystal structure of the surfactin synthetase-activating enzyme Sfp: a prototype of the 4'-phosphopantetheinyl transferase superfamily FREE

    Klaus Reuter, Mohammad R. Mofid, Mohamed A. Marahiel and Ralf Ficner

    The EMBO Journal (1999), 18, - 6823 - 6831, doi:10.1093/emboj/18.23.6823

    • Abstract - Crystal structure of the surfactin synthetase-activating enzyme Sfp: a prototype of the 4[prime]-phosphopantetheinyl transferase superfamily
    • Full text
    • PDF (914 KB) - Crystal structure of the surfactin synthetase-activating enzyme Sfp: a prototype of the 4[prime]-phosphopantetheinyl transferase superfamily

  • The E2–E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain FREE

    Youming Xie and Alexander Varshavsky

    The EMBO Journal (1999), 18, - 6832 - 6844, doi:10.1093/emboj/18.23.6832

    • Abstract - The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain
    • Full text
    • PDF (596 KB) - The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain

  • Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation FREE

    Dmitry V. Bulavin, Shiichi Saito, M. Christine Hollander, Kazuyasu Sakaguchi, Carl W. Anderson, Ettore Appella and Albert J. Fornace Jr

    The EMBO Journal (1999), 18, - 6845 - 6854, doi:10.1093/emboj/18.23.6845

    • Abstract - Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation
    • Full text
    • PDF (629 KB) - Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation

  • A single amino acid alteration (101L) introduced into murine PrP dramatically alters incubation time of transmissible spongiform encephalopathy FREE

    Jean C. Manson, Elizabeth Jamieson, Herbert Baybutt, Nadia L. Tuzi, Rona Barron, Irene McConnell, Robert Somerville, James Ironside, Robert Will, Man-Sun Sy, David W. Melton, James Hope and Christopher Bostock

    The EMBO Journal (1999), 18, - 6855 - 6864, doi:10.1093/emboj/18.23.6855

    • Abstract - A single amino acid alteration (101L) introduced into murine PrP dramatically alters incubation time of transmissible spongiform encephalopathy
    • Full text
    • PDF (1,131 KB) - A single amino acid alteration (101L) introduced into murine PrP dramatically alters incubation time of transmissible spongiform encephalopathy

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