Table of Contents : The EMBO Journal

Volume 18, Number 22
15 November 1999

pp 6201-6582

EMBO Workshop Report
Top of page
- Steroid and nuclear receptors Villefranche-sur-Mer, France, May 25–27, 1999 FREE
  Luciano Di Croce, Sam Okret, Sander Kersten, Jan-Åke Gustafsson, Malcolm Parker, Walter Wahli and Miguel Beato
  The EMBO Journal (1999), 18, - 6201 - 6210, doi:10.1093/emboj/18.22.6201
  - Full text
  - PDF (410 KB) - Steroid and nuclear receptors Villefranche-sur-Mer, France, May 25-27, 1999
Articles
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- Membrane raft microdomains mediate front–rear polarity in migrating cells FREE
  Santos Mañes, Emilia Mira, Concepción Gómez-Moutón, Rosa Ana Lacalle, Patrick Keller, Juan Pablo Labrador and Carlos Martínez-A
  The EMBO Journal (1999), 18, - 6211 - 6220, doi:10.1093/emboj/18.22.6211
  - Abstract - Membrane raft microdomains mediate front-rear polarity in migrating cells
  - Full text
  - PDF (447 KB) - Membrane raft microdomains mediate front-rear polarity in migrating cells
- CTRP is essential for mosquito infection by malaria ookinetes FREE
  Johannes T. Dessens, Annette L. Beetsma, George Dimopoulos, Kai Wengelnik, Andrea Crisanti, Fotis C. Kafatos and Robert E. Sinden
  The EMBO Journal (1999), 18, - 6221 - 6227, doi:10.1093/emboj/18.22.6221
  - Abstract - CTRP is essential for mosquito infection by malaria ookinetes
  - Full text
  - PDF (161 KB) - CTRP is essential for mosquito infection by malaria ookinetes
- Crystal structure of human 2-glycoprotein I: implications for phospholipid binding and the antiphospholipid syndrome FREE
  Robert Schwarzenbacher, Kornelius Zeth, Kay Diederichs, Anna Gries, Gerhard M. Kostner, Peter Laggner and Ruth Prassl
  The EMBO Journal (1999), 18, - 6228 - 6239, doi:10.1093/emboj/18.22.6228
  - Abstract - Crystal structure of human [beta]2-glycoprotein I: implications for phospholipid binding and the antiphospholipid syndrome
  - Full text
  - PDF (593 KB) - Crystal structure of human [beta]2-glycoprotein I: implications for phospholipid binding and the antiphospholipid syndrome
- Structural basis and potential role of heparin/heparan sulfate binding to the angiogenesis inhibitor endostatin FREE
  Takako Sasaki, Helena Larsson, Johan Kreuger, Markku Salmivirta, Lena Claesson-Welsh, Ulf Lindahl, Erhard Hohenester and Rupert Timpl
  The EMBO Journal (1999), 18, - 6240 - 6248, doi:10.1093/emboj/18.22.6240
  - Abstract - Structural basis and potential role of heparin/heparan sulfate binding to the angiogenesis inhibitor endostatin
  - Full text
  - PDF (305 KB) - Structural basis and potential role of heparin/heparan sulfate binding to the angiogenesis inhibitor endostatin
- Structural studies of two rhinovirus serotypes complexed with fragments of their cellular receptor FREE
  Prasanna R. Kolatkar, Jordi Bella, Norman H. Olson, Carol M. Bator, Timothy S. Baker and Michael G. Rossmann
  The EMBO Journal (1999), 18, - 6249 - 6259, doi:10.1093/emboj/18.22.6249
  - Abstract - Structural studies of two rhinovirus serotypes complexed with fragments of their cellular receptor
  - Full text
  - PDF (542 KB) - Structural studies of two rhinovirus serotypes complexed with fragments of their cellular receptor
- Inducible nitric oxide synthase: role of the N-terminal -hairpin hook and pterin-binding segment in dimerization and tetrahydrobiopterin interaction FREE
  Dipak K. Ghosh, Brian R. Crane, Sanjay Ghosh, Dennis Wolan, Ratan Gachhui, Carol Crooks, Anthony Presta, John A. Tainer, Elizabeth D. Getzoff and Dennis J. Stuehr
  The EMBO Journal (1999), 18, - 6260 - 6270, doi:10.1093/emboj/18.22.6260
  - Abstract - Inducible nitric oxide synthase: role of the N-terminal [beta]-hairpin hook and pterin-binding segment in dimerization and tetrahydrobiopterin interaction
  - Full text
  - PDF (483 KB) - Inducible nitric oxide synthase: role of the N-terminal [beta]-hairpin hook and pterin-binding segment in dimerization and tetrahydrobiopterin interaction
- N-terminal domain swapping and metal ion binding in nitric oxide synthase dimerization FREE
  Brian R. Crane, Robin J. Rosenfeld, Andrew S. Arvai, Dipak K. Ghosh, Sanjay Ghosh, John A. Tainer, Dennis J. Stuehr and Elizabeth D. Getzoff
  The EMBO Journal (1999), 18, - 6271 - 6281, doi:10.1093/emboj/18.22.6271
  - Abstract - N-terminal domain swapping and metal ion binding in nitric oxide synthase dimerization
  - Full text
  - PDF (584 KB) - N-terminal domain swapping and metal ion binding in nitric oxide synthase dimerization
- Heme deficiency in erythroid lineage causes differentiation arrest and cytoplasmic iron overload FREE
  Osamu Nakajima, Satoru Takahashi, Hideo Harigae, Kazumichi Furuyama, Norio Hayashi, Shigeru Sassa and Masayuki Yamamoto
  The EMBO Journal (1999), 18, - 6282 - 6289, doi:10.1093/emboj/18.22.6282
  - Abstract - Heme deficiency in erythroid lineage causes differentiation arrest and cytoplasmic iron overload
  - Full text
  - PDF (380 KB) - Heme deficiency in erythroid lineage causes differentiation arrest and cytoplasmic iron overload
- An unstable transmembrane segment in the cystic fibrosis transmembrane conductance regulator FREE
  Matthew Tector and F. Ulrich Hartl
  The EMBO Journal (1999), 18, - 6290 - 6298, doi:10.1093/emboj/18.22.6290
  - Abstract - An unstable transmembrane segment in the cystic fibrosis transmembrane conductance regulator
  - Full text
  - PDF (275 KB) - An unstable transmembrane segment in the cystic fibrosis transmembrane conductance regulator
- Hydrophobic forces drive spontaneous membrane insertion of the bacteriophage Pf3 coat protein without topological control FREE
  Dorothee Kiefer and Andreas Kuhn
  The EMBO Journal (1999), 18, - 6299 - 6306, doi:10.1093/emboj/18.22.6299
  - Abstract - Hydrophobic forces drive spontaneous membrane insertion of the bacteriophage Pf3 coat protein without topological control
  - Full text
  - PDF (260 KB) - Hydrophobic forces drive spontaneous membrane insertion of the bacteriophage Pf3 coat protein without topological control
- E2A activity is induced during B-cell activation to promote immunoglobulin class switch recombination FREE
  Melanie W. Quong, David P. Harris, Susan L. Swain and Cornelis Murre
  The EMBO Journal (1999), 18, - 6307 - 6318, doi:10.1093/emboj/18.22.6307
  - Abstract - E2A activity is induced during B-cell activation to promote immunoglobulin class switch recombination
  - Full text
  - PDF (588 KB) - E2A activity is induced during B-cell activation to promote immunoglobulin class switch recombination
- Efficient antibody diversification by gene conversion in vivo in the absence of selection for V(D)J-encoded determinants FREE
  Camil E. Sayegh, Gillian Drury and Michael J.H. Ratcliffe
  The EMBO Journal (1999), 18, - 6319 - 6328, doi:10.1093/emboj/18.22.6319
  - Abstract - Efficient antibody diversification by gene conversion : in vivo: in the absence of selection for V(D)J-encoded determinants
  - Full text
  - PDF (383 KB) - Efficient antibody diversification by gene conversion : in vivo: in the absence of selection for V(D)J-encoded determinants
- Ca²⁺ bridges the C2 membrane-binding domain of protein kinase C directly to phosphatidylserine FREE
  Nuria Verdaguer, Senena Corbalan-Garcia, Wendy F. Ochoa, Ignacio Fita and Juan C. Gómez-Fernández
  The EMBO Journal (1999), 18, - 6329 - 6338, doi:10.1093/emboj/18.22.6329
  - Abstract - Ca: 2+: bridges the C2 membrane-binding domain of protein kinase C[alpha] directly to phosphatidylserine
  - Full text
  - PDF (574 KB) - Ca: 2+: bridges the C2 membrane-binding domain of protein kinase C[alpha] directly to phosphatidylserine
- Loss of receptor regulation by a phospholipase D1 mutant unresponsive to protein kinase C FREE
  Yue Zhang, Yelena M. Altshuller, Scott M. Hammond, Andrew J. Morris and Michael A. Frohman
  The EMBO Journal (1999), 18, - 6339 - 6348, doi:10.1093/emboj/18.22.6339
  - Abstract - Loss of receptor regulation by a phospholipase D1 mutant unresponsive to protein kinase C
  - Full text
  - PDF (447 KB) - Loss of receptor regulation by a phospholipase D1 mutant unresponsive to protein kinase C
- Apoptosis driven by IP₃-linked mitochondrial calcium signals FREE
  Gábor Szalai, Rajeshwari Krishnamurthy and György Hajnóczky
  The EMBO Journal (1999), 18, - 6349 - 6361, doi:10.1093/emboj/18.22.6349
  - Abstract - Apoptosis driven by IP: 3: -linked mitochondrial calcium signals
  - Full text
  - PDF (545 KB) - Apoptosis driven by IP: 3: -linked mitochondrial calcium signals
- The downregulation of the pro-apoptotic protein Par-4 is critical for Ras-induced survival and tumor progression FREE
  Marta Barradas, Alicia Monjas, María T. Diaz-Meco, Manuel Serrano and Jorge Moscat
  The EMBO Journal (1999), 18, - 6362 - 6369, doi:10.1093/emboj/18.22.6362
  - Abstract - The downregulation of the pro-apoptotic protein Par-4 is critical for Ras-induced survival and tumor progression
  - Full text
  - PDF (252 KB) - The downregulation of the pro-apoptotic protein Par-4 is critical for Ras-induced survival and tumor progression
- Functional diversity of LAP2 and LAP2 in postmitotic chromosome association is caused by an -specific nuclear targeting domain FREE
  Sylvia Vlcek, Herwig Just, Thomas Dechat and Roland Foisner
  The EMBO Journal (1999), 18, - 6370 - 6384, doi:10.1093/emboj/18.22.6370
  - Abstract - Functional diversity of LAP2[alpha] and LAP2[beta] in postmitotic chromosome association is caused by an [alpha]-specific nuclear targeting domain
  - Full text
  - PDF (671 KB) - Functional diversity of LAP2[alpha] and LAP2[beta] in postmitotic chromosome association is caused by an [alpha]-specific nuclear targeting domain
- Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family FREE
  Anders L. Nielsen, José A. Ortiz, Jun You, Mustapha Oulad-Abdelghani, Ruben Khechumian, Anne Gansmuller, Pierre Chambon and Régine Losson
  The EMBO Journal (1999), 18, - 6385 - 6395, doi:10.1093/emboj/18.22.6385
  - Abstract - Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family
  - Full text
  - PDF (471 KB) - Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family
- Human HMG box transcription factor HBP1: a role in hCD2 LCR function FREE
  Talgat Zhuma, Richard Tyrrell, Belaïd Sekkali, George Skavdis, Alexander Saveliev, Mauro Tolaini, Kathleen Roderick, Trisha Norton, Steve Smerdon, Steve Sedgwick, Richard Festenstein and Dimitris Kioussis
  The EMBO Journal (1999), 18, - 6396 - 6406, doi:10.1093/emboj/18.22.6396
  - Abstract - Human HMG box transcription factor HBP1: a role in hCD2 LCR function
  - Full text
  - PDF (568 KB) - Human HMG box transcription factor HBP1: a role in hCD2 LCR function
- Chromatin remodelling at the PHO8 promoter requires SWI–SNF and SAGA at a step subsequent to activator binding FREE
  Philip D. Gregory, Andrea Schmid, Maasoumeh Zavari, Martin Münsterkötter and Wolfram Hörz
  The EMBO Journal (1999), 18, - 6407 - 6414, doi:10.1093/emboj/18.22.6407
  - Abstract - Chromatin remodelling at the : PHO8: promoter requires SWI-SNF and SAGA at a step subsequent to activator binding
  - Full text
  - PDF (251 KB) - Chromatin remodelling at the : PHO8: promoter requires SWI-SNF and SAGA at a step subsequent to activator binding
- Constitutive silencing of IFN- promoter is mediated by NRF (NF-B-repressing factor), a nuclear inhibitor of NF-B FREE
  Mahtab Nourbakhsh and Hansjörg Hauser
  The EMBO Journal (1999), 18, - 6415 - 6425, doi:10.1093/emboj/18.22.6415
  - Abstract - Constitutive silencing of IFN-[beta] promoter is mediated by NRF (NF-[kappa]B-repressing factor), a nuclear inhibitor of NF-[kappa]B
  - Full text
  - PDF (369 KB) - Constitutive silencing of IFN-[beta] promoter is mediated by NRF (NF-[kappa]B-repressing factor), a nuclear inhibitor of NF-[kappa]B
- The mesoderm determinant Snail collaborates with related zinc-finger proteins to control Drosophila neurogenesis FREE
  Shovon I. Ashraf, Xiaodi Hu, John Roote and Y. Tony Ip
  The EMBO Journal (1999), 18, - 6426 - 6438, doi:10.1093/emboj/18.22.6426
  - Abstract - The mesoderm determinant Snail collaborates with related zinc-finger proteins to control : Drosophila: neurogenesis
  - Full text
  - PDF (710 KB) - The mesoderm determinant Snail collaborates with related zinc-finger proteins to control : Drosophila: neurogenesis
- Proteasome-mediated degradation of transcriptional activators correlates with activation domain potency in vivo FREE
  Elizabeth Molinari, Michael Gilman and Sridaran Natesan
  The EMBO Journal (1999), 18, - 6439 - 6447, doi:10.1093/emboj/18.22.6439
  - Abstract - Proteasome-mediated degradation of transcriptional activators correlates with activation domain potency : in vivo
  - Full text
  - PDF (214 KB) - Proteasome-mediated degradation of transcriptional activators correlates with activation domain potency : in vivo
- Sum1 and Hst1 repress middle sporulation-specific gene expression during mitosis in Saccharomyces cerevisiae FREE
  Jianxin Xie, Michael Pierce, Valérie Gailus-Durner, Marisa Wagner, Edward Winter and Andrew K. Vershon
  The EMBO Journal (1999), 18, - 6448 - 6454, doi:10.1093/emboj/18.22.6448
  - Abstract - Sum1 and Hst1 repress middle sporulation-specific gene expression during mitosis in : Saccharomyces cerevisiae
  - Full text
  - PDF (257 KB) - Sum1 and Hst1 repress middle sporulation-specific gene expression during mitosis in : Saccharomyces cerevisiae
- SUMO-1 modification activates the transcriptional response of p53 FREE
  Manuel S. Rodriguez, Joana M. P. Desterro, Sonia Lain, Carol A. Midgley, David P. Lane and Ronald T. Hay
  The EMBO Journal (1999), 18, - 6455 - 6461, doi:10.1093/emboj/18.22.6455
  - Abstract - SUMO-1 modification activates the transcriptional response of p53
  - Full text
  - PDF (190 KB) - SUMO-1 modification activates the transcriptional response of p53
- Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1 FREE
  Monica Gostissa, Arnd Hengstermann, Valentina Fogal, Peter Sandy, Sylvia E. Schwarz, Martin Scheffner and Giannino Del Sal
  The EMBO Journal (1999), 18, - 6462 - 6471, doi:10.1093/emboj/18.22.6462
  - Abstract - Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1
  - Full text
  - PDF (329 KB) - Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1
- Hinge-helix formation and DNA bending in various lac repressor–operator complexes FREE
  Christian A. E. M. Spronk, Gert E. Folkers, Anne-Marie G. W. Noordman, Rainer Wechselberger, Nienke van den Brink, Rolf Boelens and Robert Kaptein
  The EMBO Journal (1999), 18, - 6472 - 6480, doi:10.1093/emboj/18.22.6472
  - Abstract - Hinge-helix formation and DNA bending in various : lac: repressor-operator complexes
  - Full text
  - PDF (458 KB) - Hinge-helix formation and DNA bending in various : lac: repressor-operator complexes
- A factor related to pseudouridine synthases is required for chloroplast group II intron trans-splicing in Chlamydomonas reinhardtii FREE
  Karl Perron, Michel Goldschmidt-Clermont and Jean-David Rochaix
  The EMBO Journal (1999), 18, - 6481 - 6490, doi:10.1093/emboj/18.22.6481
  - Abstract - A factor related to pseudouridine synthases is required for chloroplast group II intron : trans: -splicing in : Chlamydomonas reinhardtii
  - Full text
  - PDF (407 KB) - A factor related to pseudouridine synthases is required for chloroplast group II intron : trans: -splicing in : Chlamydomonas reinhardtii
- Self-splicing of the Tetrahymena intron from mRNA in mammalian cells FREE
  Moira Hagen and Thomas R. Cech
  The EMBO Journal (1999), 18, - 6491 - 6500, doi:10.1093/emboj/18.22.6491
  - Abstract - Self-splicing of the : Tetrahymena: intron from mRNA in mammalian cells
  - Full text
  - PDF (330 KB) - Self-splicing of the : Tetrahymena: intron from mRNA in mammalian cells
- Major rearrangements in the 70S ribosomal 3D structure caused by a conformational switch in 16S ribosomal RNA FREE
  Irene S. Gabashvili, Rajendra K. Agrawal, Robert Grassucci, Catherine L. Squires, Albert E. Dahlberg and Joachim Frank
  The EMBO Journal (1999), 18, - 6501 - 6507, doi:10.1093/emboj/18.22.6501
  - Abstract - Major rearrangements in the 70S ribosomal 3D structure caused by a conformational switch in 16S ribosomal RNA
  - Full text
  - PDF (361 KB) - Major rearrangements in the 70S ribosomal 3D structure caused by a conformational switch in 16S ribosomal RNA
- The NMR structure of the 5S rRNA E-domain–protein L25 complex shows preformed and induced recognition FREE
  Matthias Stoldt, Jens Wöhnert, Oliver Ohlenschläger, Matthias Görlach and Larry R. Brown
  The EMBO Journal (1999), 18, - 6508 - 6521, doi:10.1093/emboj/18.22.6508
  - Abstract - The NMR structure of the 5S rRNA E-domain-protein L25 complex shows preformed and induced recognition
  - Full text
  - PDF (1,086 KB) - The NMR structure of the 5S rRNA E-domain-protein L25 complex shows preformed and induced recognition
- A new class of enzyme acting on damaged ribosomes: ribosomal RNA apurinic site specific lyase found in wheat germ FREE
  Tomio Ogasawara, Tatsuya Sawasaki, Ryo Morishita, Akihiko Ozawa, Kairat Madin and Yaeta Endo
  The EMBO Journal (1999), 18, - 6522 - 6531, doi:10.1093/emboj/18.22.6522
  - Abstract - A new class of enzyme acting on damaged ribosomes: ribosomal RNA apurinic site specific lyase found in wheat germ
  - Full text
  - PDF (478 KB) - A new class of enzyme acting on damaged ribosomes: ribosomal RNA apurinic site specific lyase found in wheat germ
- Synthesis of aspartyl-tRNA^Asp in Escherichia coli—a snapshot of the second step FREE
  S. Eiler, A.-C. Dock-Bregeon, L. Moulinier, J.-C. Thierry and D. Moras
  The EMBO Journal (1999), 18, - 6532 - 6541, doi:10.1093/emboj/18.22.6532
  - Abstract - Synthesis of aspartyl-tRNA: Asp: in : Escherichia coli: [mdash]a snapshot of the second step
  - Full text
  - PDF (426 KB) - Synthesis of aspartyl-tRNA: Asp: in : Escherichia coli: [mdash]a snapshot of the second step
- Asymmetry of Dam remethylation on the leading and lagging arms of plasmid replicative intermediates FREE
  Irina Stancheva, Theodor Koller and José M. Sogo
  The EMBO Journal (1999), 18, - 6542 - 6551, doi:10.1093/emboj/18.22.6542
  - Abstract - Asymmetry of Dam remethylation on the leading and lagging arms of plasmid replicative intermediates
  - Full text
  - PDF (363 KB) - Asymmetry of Dam remethylation on the leading and lagging arms of plasmid replicative intermediates
- The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51 FREE
  Jean-Yves Masson, Adelina A. Davies, Nasser Hajibagheri, Eric Van Dyck, Fiona E. Benson, Alicja Z. Stasiak, Andrzej Stasiak and Stephen C. West
  The EMBO Journal (1999), 18, - 6552 - 6560, doi:10.1093/emboj/18.22.6552
  - Abstract - The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51
  - Full text
  - PDF (274 KB) - The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51
- Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase FREE
  Achille Pellicioli, Chiara Lucca, Giordano Liberi, Federica Marini, Massimo Lopes, Paolo Plevani, Alfredo Romano, Pier Paolo Di Fiore and Marco Foiani
  The EMBO Journal (1999), 18, - 6561 - 6572, doi:10.1093/emboj/18.22.6561
  - Abstract - Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase
  - Full text
  - PDF (382 KB) - Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase
- The modified base J is the target for a nove lDNA-binding protein in kinetoplastid protozoans FREE
  Mike Cross, Rudo Kieft, Robert Sabatini, Matthias Wilm, Martin de Kort, Gijs A. van der Marel, Jacques H. van Boom, Fred van Leeuwen and Piet Borst
  The EMBO Journal (1999), 18, - 6573 - 6581, doi:10.1093/emboj/18.22.6573
  - Abstract - The modified base J is the target for a nove lDNA-binding protein in kinetoplastid protozoans
  - Full text
  - PDF (334 KB) - The modified base J is the target for a nove lDNA-binding protein in kinetoplastid protozoans
Corrigendum
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- Membrane trafficking and the cytoskeleton: an integrated view Santa Maria Imbaro, Italy, June 26–30, 1999 FREE
  Roger D. Sloboda
  The EMBO Journal (1999), 18, - 6582, doi:10.1038/sj.emboj.7592059
  - Full text
  - PDF (24 KB) - Membrane trafficking and the cytoskeleton: an integrated view Santa Maria Imbaro, Italy, June 26-30, 1999

Table of Contents

Volume 18, Number 22 15 November 1999

EMBO Workshop Report

Steroid and nuclear receptors Villefranche-sur-Mer, France, May 25–27, 1999 FREE

Articles

Membrane raft microdomains mediate front–rear polarity in migrating cells FREE

CTRP is essential for mosquito infection by malaria ookinetes FREE

Crystal structure of human 2-glycoprotein I: implications for phospholipid binding and the antiphospholipid syndrome FREE

Structural basis and potential role of heparin/heparan sulfate binding to the angiogenesis inhibitor endostatin FREE

Structural studies of two rhinovirus serotypes complexed with fragments of their cellular receptor FREE

Inducible nitric oxide synthase: role of the N-terminal -hairpin hook and pterin-binding segment in dimerization and tetrahydrobiopterin interaction FREE

N-terminal domain swapping and metal ion binding in nitric oxide synthase dimerization FREE

Heme deficiency in erythroid lineage causes differentiation arrest and cytoplasmic iron overload FREE

An unstable transmembrane segment in the cystic fibrosis transmembrane conductance regulator FREE

Hydrophobic forces drive spontaneous membrane insertion of the bacteriophage Pf3 coat protein without topological control FREE

E2A activity is induced during B-cell activation to promote immunoglobulin class switch recombination FREE

Efficient antibody diversification by gene conversion in vivo in the absence of selection for V(D)J-encoded determinants FREE

Ca2+ bridges the C2 membrane-binding domain of protein kinase C directly to phosphatidylserine FREE

Loss of receptor regulation by a phospholipase D1 mutant unresponsive to protein kinase C FREE

Apoptosis driven by IP3-linked mitochondrial calcium signals FREE

The downregulation of the pro-apoptotic protein Par-4 is critical for Ras-induced survival and tumor progression FREE

Functional diversity of LAP2 and LAP2 in postmitotic chromosome association is caused by an -specific nuclear targeting domain FREE

Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family FREE

Human HMG box transcription factor HBP1: a role in hCD2 LCR function FREE

Chromatin remodelling at the PHO8 promoter requires SWI–SNF and SAGA at a step subsequent to activator binding FREE

Constitutive silencing of IFN- promoter is mediated by NRF (NF-B-repressing factor), a nuclear inhibitor of NF-B FREE

The mesoderm determinant Snail collaborates with related zinc-finger proteins to control Drosophila neurogenesis FREE

Proteasome-mediated degradation of transcriptional activators correlates with activation domain potency in vivo FREE

Sum1 and Hst1 repress middle sporulation-specific gene expression during mitosis in Saccharomyces cerevisiae FREE

SUMO-1 modification activates the transcriptional response of p53 FREE

Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1 FREE

Hinge-helix formation and DNA bending in various lac repressor–operator complexes FREE

A factor related to pseudouridine synthases is required for chloroplast group II intron trans-splicing in Chlamydomonas reinhardtii FREE

Self-splicing of the Tetrahymena intron from mRNA in mammalian cells FREE

Major rearrangements in the 70S ribosomal 3D structure caused by a conformational switch in 16S ribosomal RNA FREE

The NMR structure of the 5S rRNA E-domain–protein L25 complex shows preformed and induced recognition FREE

A new class of enzyme acting on damaged ribosomes: ribosomal RNA apurinic site specific lyase found in wheat germ FREE

Synthesis of aspartyl-tRNAAsp in Escherichia coli—a snapshot of the second step FREE

Asymmetry of Dam remethylation on the leading and lagging arms of plasmid replicative intermediates FREE

The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51 FREE

Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase FREE

The modified base J is the target for a nove lDNA-binding protein in kinetoplastid protozoans FREE

Corrigendum

Membrane trafficking and the cytoskeleton: an integrated view Santa Maria Imbaro, Italy, June 26–30, 1999 FREE

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Volume 18, Number 22
15 November 1999

Ca²⁺ bridges the C2 membrane-binding domain of protein kinase C directly to phosphatidylserine FREE

Apoptosis driven by IP₃-linked mitochondrial calcium signals FREE

Synthesis of aspartyl-tRNA^Asp in Escherichia coli—a snapshot of the second step FREE