Table of Contents : The EMBO Journal

Volume 17, Number 22
16 November 1998

pp 6427-6766

EMBO Members Review
Top of page
- Replication errors: cha(lle)nging the genome FREE
  Josef Jiricny
  The EMBO Journal (1998), 17, - 6427 - 6436, doi:10.1093/emboj/17.22.6427
Articles
Top of page
- Structural origins of gentamicin antibiotic action FREE
  Satoko Yoshizawa, Dominique Fourmy and Joseph D. Puglisi
  The EMBO Journal (1998), 17, - 6437 - 6448, doi:10.1093/emboj/17.22.6437
  - Abstract - Structural origins of gentamicin antibiotic action
  - Full text
  - PDF (647 KB) - Structural origins of gentamicin antibiotic action
- A novel complex of membrane proteins required for formation of a spherical nucleus FREE
  Symeon Siniossoglou, Helena Santos-Rosa, Juri Rappsilber, Mathias Mann and Ed Hurt
  The EMBO Journal (1998), 17, - 6449 - 6464, doi:10.1093/emboj/17.22.6449
  - Abstract - A novel complex of membrane proteins required for formation of a spherical nucleus
  - Full text
  - PDF (970 KB) - A novel complex of membrane proteins required for formation of a spherical nucleus
- Localization of the 26S proteasome during mitosis and meiosis in fission yeast FREE
  Caroline R.M. Wilkinson, Mairi Wallace, Mary Morphew, Paul Perry, Robin Allshire, Jean-Paul Javerzat, J.Richard McIntosh and Colin Gordon
  The EMBO Journal (1998), 17, - 6465 - 6476, doi:10.1093/emboj/17.22.6465
  - Abstract - Localization of the 26S proteasome during mitosis and meiosis in fission yeast
  - Full text
  - PDF (601 KB) - Localization of the 26S proteasome during mitosis and meiosis in fission yeast
- Tim9p, an essential partner subunit of Tim10p for the import of mitochondrial carrier proteins FREE
  Carla M. Koehler, Sabeeha Merchant, Wolfgang Oppliger, Karl Schmid, Ernst Jarosch, Luisita Dolfini, Tina Junne, Gottfried Schatz and Kostas Tokatlidis
  The EMBO Journal (1998), 17, - 6477 - 6486, doi:10.1093/emboj/17.22.6477
  - Abstract - Tim9p, an essential partner subunit of Tim10p for the import of mitochondrial carrier proteins
  - Full text
  - PDF (475 KB) - Tim9p, an essential partner subunit of Tim10p for the import of mitochondrial carrier proteins
- Substrate-induced assembly of a contiguous channel for protein export from E.coli: reversible bridging of an inner-membrane translocase to an outer membrane exit pore FREE
  Thirumaran Thanabalu, Eva Koronakis, Colin Hughes and Vassilis Koronakis
  The EMBO Journal (1998), 17, - 6487 - 6496, doi:10.1093/emboj/17.22.6487
  - Abstract - Substrate-induced assembly of a contiguous channel for protein export from : E.coli: : reversible bridging of an inner-membrane translocase to an outer membrane exit pore
  - Full text
  - PDF (414 KB) - Substrate-induced assembly of a contiguous channel for protein export from : E.coli: : reversible bridging of an inner-membrane translocase to an outer membrane exit pore
- Unfolding of preproteins upon import into mitochondria FREE
  Brigitte Gaume, Christian Klaus, Christian Ungermann, Bernard Guiard, Walter Neupert and Michael Brunner
  The EMBO Journal (1998), 17, - 6497 - 6507, doi:10.1093/emboj/17.22.6497
  - Abstract - Unfolding of preproteins upon import into mitochondria
  - Full text
  - PDF (455 KB) - Unfolding of preproteins upon import into mitochondria
- C- to N-terminal translocation of preproteins into mitochondria FREE
  Heike Fölsch, Brigitte Gaume, Michael Brunner, Walter Neupert and Rosemary A. Stuart
  The EMBO Journal (1998), 17, - 6508 - 6515, doi:10.1093/emboj/17.22.6508
  - Abstract - C- to N-terminal translocation of preproteins into mitochondria
  - Full text
  - PDF (327 KB) - C- to N-terminal translocation of preproteins into mitochondria
- The essential role of profilin in the assembly of actin for microspike formation FREE
  Shiro Suetsugu, Hiroaki Miki and Tadaomi Takenawa
  The EMBO Journal (1998), 17, - 6516 - 6526, doi:10.1093/emboj/17.22.6516
  - Abstract - The essential role of profilin in the assembly of actin for microspike formation
  - Full text
  - PDF (538 KB) - The essential role of profilin in the assembly of actin for microspike formation
- PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia FREE
  Arie Abo, Jian Qu, Marta S. Cammarano, Chuntao Dan, Alexandra Fritsch, Veronique Baud, Barbara Belisle and Audrey Minden
  The EMBO Journal (1998), 17, - 6527 - 6540, doi:10.1093/emboj/17.22.6527
  - Abstract - PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia
  - Full text
  - PDF (728 KB) - PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia
- Recognition specificity of individual EH domains of mammals and yeast FREE
  Serena Paoluzi, Luisa Castagnoli, Ilde Lauro, Anna Elisabetta Salcini, Laura Coda, Silvia Fre´, Stefano Confalonieri, Pier Giuseppe Pelicci, Pier Paolo Di Fiore and Gianni Cesareni
  The EMBO Journal (1998), 17, - 6541 - 6550, doi:10.1093/emboj/17.22.6541
  - Abstract - Recognition specificity of individual EH domains of mammals and yeast
  - Full text
  - PDF (815 KB) - Recognition specificity of individual EH domains of mammals and yeast
- Functional dissection of the cytoplasmic subregions of the IL-2 receptor c chain in primary lymphocyte populations FREE
  Hodaka Fujii, Kouetsu Ogasawara, Hidefumi Otsuka, Misao Suzuki, Ken-ichi Yamamura, Taeko Yokochi, Tadaaki Miyazaki, Haruhiko Suzuki, Tak W. Mak, Shinsuke Taki and Tadatsugu Taniguchi
  The EMBO Journal (1998), 17, - 6551 - 6557, doi:10.1093/emboj/17.22.6551
  - Abstract - Functional dissection of the cytoplasmic subregions of the IL-2 receptor [beta]c chain in primary lymphocyte populations
  - Full text
  - PDF (401 KB) - Functional dissection of the cytoplasmic subregions of the IL-2 receptor [beta]c chain in primary lymphocyte populations
- Structure of the IGF-binding domain of the insulin-like growth factor-binding protein-5 (IGFBP-5): implications for IGF and IGF-I receptor interactions FREE
  Wenzel Kalus, Markus Zweckstetter, Christian Renner, Yolanda Sanchez, Julia Georgescu, Michael Grol, Dirk Demuth, Ralf Schumacher, Carola Dony, Kurt Lang and Tad A. Holak
  The EMBO Journal (1998), 17, - 6558 - 6572, doi:10.1093/emboj/17.22.6558
  - Abstract - Structure of the IGF-binding domain of the insulin-like growth factor-binding protein-5 (IGFBP-5): implications for IGF and IGF-I receptor interactions
  - Full text
  - PDF (928 KB) - Structure of the IGF-binding domain of the insulin-like growth factor-binding protein-5 (IGFBP-5): implications for IGF and IGF-I receptor interactions
- Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of theCBP/p300 coactivator by the hypoxia-induciblefactor-1 FREE
  Pekka J. Kallio, Kensaku Okamoto, Sallyann O'Brien, Pilar Carrero, Yuichi Makino, Hirotoshi Tanaka and Lorenz Poellinger
  The EMBO Journal (1998), 17, - 6573 - 6586, doi:10.1093/emboj/17.22.6573
  - Abstract - Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of theCBP/p300 coactivator by the hypoxia-induciblefactor-1[alpha]
  - Full text
  - PDF (531 KB) - Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of theCBP/p300 coactivator by the hypoxia-induciblefactor-1[alpha]
- NTF2 mediates nuclear import of Ran FREE
  Katharina Ribbeck, Gerd Lipowsky, Helen M. Kent, Murray Stewart and Dirk Görlich
  The EMBO Journal (1998), 17, - 6587 - 6598, doi:10.1093/emboj/17.22.6587
  - Abstract - NTF2 mediates nuclear import of Ran
  - Full text
  - PDF (599 KB) - NTF2 mediates nuclear import of Ran
- A novel context for the 'MutT' module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase FREE
  Stephen T. Safrany, James J. Caffrey, Xiaonian Yang, Michael E. Bembenek, Mary B. Moyer, William A. Burkhart and Stephen B. Shears
  The EMBO Journal (1998), 17, - 6599 - 6607, doi:10.1093/emboj/17.22.6599
  - Abstract - A novel context for the 'MutT' module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase
  - Full text
  - PDF (458 KB) - A novel context for the 'MutT' module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase
- Phosphorylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2 FREE
  Kornel E. Schuebel, Nieves Movilla, José Luis Rosa and Xosé R. Bustelo
  The EMBO Journal (1998), 17, - 6608 - 6621, doi:10.1093/emboj/17.22.6608
  - Abstract - Phosphorylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2
  - Full text
  - PDF (784 KB) - Phosphorylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2
- Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival FREE
  Laura Moro, Mascia Venturino, Chiarella Bozzo, Lorenzo Silengo, Fiorella Altruda, Laura Beguinot, Guido Tarone and Paola Defilippi
  The EMBO Journal (1998), 17, - 6622 - 6632, doi:10.1093/emboj/17.22.6622
  - Abstract - Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival
  - Full text
  - PDF (424 KB) - Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival
- Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade FREE
  Ferruccio Galbiati, Daniela Volonté, Jeffrey A. Engelman, Genichi Watanabe, Robert Burk, Richard G. Pestell and Michael P. Lisanti
  The EMBO Journal (1998), 17, - 6633 - 6648, doi:10.1093/emboj/17.22.6633
  - Abstract - Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade
  - Full text
  - PDF (1,051 KB) - Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade
- Disruption of the p70^s6k/p85^s6k gene reveals a small mouse phenotype and a new functional S6 kinase FREE
  Hiroshi Shima, Mario Pende, Yi Chen, Stefano Fumagalli, George Thomas and Sara C. Kozma
  The EMBO Journal (1998), 17, - 6649 - 6659, doi:10.1093/emboj/17.22.6649
  - Abstract - Disruption of the p70: s6k: /p85: s6k: gene reveals a small mouse phenotype and a new functional S6 kinase
  - Full text
  - PDF (511 KB) - Disruption of the p70: s6k: /p85: s6k: gene reveals a small mouse phenotype and a new functional S6 kinase
- Differential viral induction of distinct interferon- genes by positive feedback through interferon regulatory factor-7 FREE
  Isabelle Marié, Joan E. Durbin and David E. Levy
  The EMBO Journal (1998), 17, - 6660 - 6669, doi:10.1093/emboj/17.22.6660
  - Abstract - Differential viral induction of distinct interferon-[alpha] genes by positive feedback through interferon regulatory factor-7
  - Full text
  - PDF (362 KB) - Differential viral induction of distinct interferon-[alpha] genes by positive feedback through interferon regulatory factor-7
- STAT3 orchestrates contradictory signals in cytokine-induced G₁ to S cell-cycle transition FREE
  Toshiyuki Fukada, Takuya Ohtani, Yuichi Yoshida, Takahiro Shirogane, Keigo Nishida, Koichi Nakajima, Masahiko Hibi and Toshio Hirano
  The EMBO Journal (1998), 17, - 6670 - 6677, doi:10.1093/emboj/17.22.6670
  - Abstract - STAT3 orchestrates contradictory signals in cytokine-induced G: 1: to S cell-cycle transition
  - Full text
  - PDF (521 KB) - STAT3 orchestrates contradictory signals in cytokine-induced G: 1: to S cell-cycle transition
- Control of Swe1p degradation by the morphogenesis checkpoint FREE
  Rey A.L. Sia, Elaine S.G. Bardes and Daniel J. Lew
  The EMBO Journal (1998), 17, - 6678 - 6688, doi:10.1093/emboj/17.22.6678
  - Abstract - Control of Swe1p degradation by the morphogenesis checkpoint
  - Full text
  - PDF (573 KB) - Control of Swe1p degradation by the morphogenesis checkpoint
- Rescue of the embryonic lethal hematopoietic defect reveals a critical role for GATA-2 in urogenital development FREE
  Yinghui Zhou, Kim-Chew Lim, Ko Onodera, Satoru Takahashi, Jun Ohta, Naoko Minegishi, Fong-Ying Tsai, Stuart H. Orkin, Masayuki Yamamoto and James Douglas Engel
  The EMBO Journal (1998), 17, - 6689 - 6700, doi:10.1093/emboj/17.22.6689
  - Abstract - Rescue of the embryonic lethal hematopoietic defect reveals a critical role for GATA-2 in urogenital development
  - Full text
  - PDF (1,035 KB) - Rescue of the embryonic lethal hematopoietic defect reveals a critical role for GATA-2 in urogenital development
- Dominant-negative suppression of HNF-1 function results in defective insulin gene transcription and impaired metabolism–secretion coupling in a pancreatic -cell line FREE
  Haiyan Wang, Pierre Maechler, Kerstin A. Hagenfeldt and Claes B. Wollheim
  The EMBO Journal (1998), 17, - 6701 - 6713, doi:10.1093/emboj/17.22.6701
  - Abstract - Dominant-negative suppression of HNF-1[alpha] function results in defective insulin gene transcription and impaired metabolism–secretion coupling in a pancreatic [beta]-cell line
  - Full text
  - PDF (664 KB) - Dominant-negative suppression of HNF-1[alpha] function results in defective insulin gene transcription and impaired metabolism–secretion coupling in a pancreatic [beta]-cell line
- Association of distinct yeast Not2 functional domains with components of Gcn5 histone acetylase and Ccr4 transcriptional regulatory complexes FREE
  John D. Benson, Mark Benson, Peter M. Howley and Kevin Struhl
  The EMBO Journal (1998), 17, - 6714 - 6722, doi:10.1093/emboj/17.22.6714
  - Abstract - Association of distinct yeast Not2 functional domains with components of Gcn5 histone acetylase and Ccr4 transcriptional regulatory complexes
  - Full text
  - PDF (310 KB) - Association of distinct yeast Not2 functional domains with components of Gcn5 histone acetylase and Ccr4 transcriptional regulatory complexes
- Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation FREE
  Hui Ge, Yuanzheng Si and Robert G. Roeder
  The EMBO Journal (1998), 17, - 6723 - 6729, doi:10.1093/emboj/17.22.6723
  - Abstract - Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation
  - Full text
  - PDF (295 KB) - Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation
- Competence in Bacillus subtilis is controlled by regulated proteolysis of a transcription factor FREE
  Kürad Turgay, Jeanette Hahn, Jan Burghoorn and David Dubnau
  The EMBO Journal (1998), 17, - 6730 - 6738, doi:10.1093/emboj/17.22.6730
  - Abstract - Competence in : Bacillus subtilis: is controlled by regulated proteolysis of a transcription factor
  - Full text
  - PDF (257 KB) - Competence in : Bacillus subtilis: is controlled by regulated proteolysis of a transcription factor
- Viral pathogenicity determinants are suppressors of transgene silencing in Nicotiana benthamiana FREE
  Gianinna Brigneti, Olivier Voinnet, Wan-Xiang Li, Liang-Hui Ji, Shou-Wei Ding and David C. Baulcombe
  The EMBO Journal (1998), 17, - 6739 - 6746, doi:10.1093/emboj/17.22.6739
  - Abstract - Viral pathogenicity determinants are suppressors of transgene silencing in : Nicotiana benthamiana
  - Full text
  - PDF (484 KB) - Viral pathogenicity determinants are suppressors of transgene silencing in : Nicotiana benthamiana
- A systematic analysis of the factors that determine the strength of pre-mRNA splicing enhancers FREE
  Brenton R. Graveley, Klemens J. Hertel and Tom Maniatis
  The EMBO Journal (1998), 17, - 6747 - 6756, doi:10.1093/emboj/17.22.6747
  - Abstract - A systematic analysis of the factors that determine the strength of pre-mRNA splicing enhancers
  - Full text
  - PDF (414 KB) - A systematic analysis of the factors that determine the strength of pre-mRNA splicing enhancers
- Crosslinking the EcoRV restriction endonuclease across the DNA-binding site reveals transient intermediates and conformational changes of the enzyme during DNA binding and catalytic turnover FREE
  Claudia Schulze, Albert Jeltsch, Ingo Franke, Claus Urbanke and Alfred Pingoud
  The EMBO Journal (1998), 17, - 6757 - 6766, doi:10.1093/emboj/17.22.6757
  - Abstract - Crosslinking the : Eco: RV restriction endonuclease across the DNA-binding site reveals transient intermediates and conformational changes of the enzyme during DNA binding and catalytic turnover
  - Full text
  - PDF (432 KB) - Crosslinking the : Eco: RV restriction endonuclease across the DNA-binding site reveals transient intermediates and conformational changes of the enzyme during DNA binding and catalytic turnover

Table of Contents

Volume 17, Number 22 16 November 1998

EMBO Members Review

Replication errors: cha(lle)nging the genome FREE

Articles

Structural origins of gentamicin antibiotic action FREE

A novel complex of membrane proteins required for formation of a spherical nucleus FREE

Localization of the 26S proteasome during mitosis and meiosis in fission yeast FREE

Tim9p, an essential partner subunit of Tim10p for the import of mitochondrial carrier proteins FREE

Substrate-induced assembly of a contiguous channel for protein export from E.coli: reversible bridging of an inner-membrane translocase to an outer membrane exit pore FREE

Unfolding of preproteins upon import into mitochondria FREE

C- to N-terminal translocation of preproteins into mitochondria FREE

The essential role of profilin in the assembly of actin for microspike formation FREE

PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia FREE

Recognition specificity of individual EH domains of mammals and yeast FREE

Functional dissection of the cytoplasmic subregions of the IL-2 receptor c chain in primary lymphocyte populations FREE

Structure of the IGF-binding domain of the insulin-like growth factor-binding protein-5 (IGFBP-5): implications for IGF and IGF-I receptor interactions FREE

Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of theCBP/p300 coactivator by the hypoxia-induciblefactor-1 FREE

NTF2 mediates nuclear import of Ran FREE

A novel context for the 'MutT' module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase FREE

Phosphorylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2 FREE

Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival FREE

Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade FREE

Disruption of the p70s6k/p85s6k gene reveals a small mouse phenotype and a new functional S6 kinase FREE

Differential viral induction of distinct interferon- genes by positive feedback through interferon regulatory factor-7 FREE

STAT3 orchestrates contradictory signals in cytokine-induced G1 to S cell-cycle transition FREE

Control of Swe1p degradation by the morphogenesis checkpoint FREE

Rescue of the embryonic lethal hematopoietic defect reveals a critical role for GATA-2 in urogenital development FREE

Dominant-negative suppression of HNF-1 function results in defective insulin gene transcription and impaired metabolism–secretion coupling in a pancreatic -cell line FREE

Association of distinct yeast Not2 functional domains with components of Gcn5 histone acetylase and Ccr4 transcriptional regulatory complexes FREE

Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation FREE

Competence in Bacillus subtilis is controlled by regulated proteolysis of a transcription factor FREE

Viral pathogenicity determinants are suppressors of transgene silencing in Nicotiana benthamiana FREE

A systematic analysis of the factors that determine the strength of pre-mRNA splicing enhancers FREE

Crosslinking the EcoRV restriction endonuclease across the DNA-binding site reveals transient intermediates and conformational changes of the enzyme during DNA binding and catalytic turnover FREE

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Volume 17, Number 22
16 November 1998

Disruption of the p70^s6k/p85^s6k gene reveals a small mouse phenotype and a new functional S6 kinase FREE

STAT3 orchestrates contradictory signals in cytokine-induced G₁ to S cell-cycle transition FREE