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Figure 1

Electron microscopic structure of agrin and mapping of its binding site in laminin-1

Alain J. Denzer, Therese Schulthess, Charlotte Fauser, Beat Schumacher, Richard A. Kammerer, Jürgen Engel and Markus A. Ruegg

  • The EMBO Journal (1998) 17, 335 - 343
  • doi:10.1093/emboj/17.2.335
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Structure and SDS–PAGE analysis of chick agrin constructs. (A) Schematic diagram of the structural domains of chick agrin and representation of the regions covered by the agrin fragments used in this study. Symbols and designations of structural domains are according to Bork and Bairoch (1995). (B) Purified agrin proteins after separation by 3–12% SDS–PAGE and visualization by silver staining. cAgrin purified by anion exchange column using Mono Q-Sepharose is shown. The molecular mass of standard proteins is given in kDa.

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