Table of Contents

Volume 17, Number 10
15 May 1998

pp 2721-2969

• Medal Review

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  • Transport into and out of the cell nucleus FREE

    Dirk Görlich

    The EMBO Journal (1998), 17, - 2721 - 2727, doi:10.1093/emboj/17.10.2721

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• Articles

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  • Nuclear export of cyclin B1 and its possible role in the DNA damage-induced G₂ checkpoint FREE

    Fumiko Toyoshima, Tetsuo Moriguchi, Atsushi Wada, Makoto Fukuda and Eisuke Nishida

    The EMBO Journal (1998), 17, - 2728 - 2735, doi:10.1093/emboj/17.10.2728

    • Abstract - Nuclear export of cyclin B1 and its possible role in the DNA damage-induced G: 2: checkpoint
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  • p53-inducible human homologue of Drosophila seven in absentia (Siah) inhibits cell growth: suppression by BAG-1 FREE

    Shu-ichi Matsuzawa, Shinichi Takayama, Barbara A. Froesch, Juan M. Zapata and John C. Reed

    The EMBO Journal (1998), 17, - 2736 - 2747, doi:10.1093/emboj/17.10.2736

    • Abstract - p53-inducible human homologue of : Drosophila seven in absentia: (Siah) inhibits cell growth: suppression by BAG-1
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  • Nine hydrophobic side chains are key determinants of the thermodynamic stability and oligomerization status of tumour suppressor p53 tetramerization domain FREE

    Mauricio G. Mateu and Alan R. Fersht

    The EMBO Journal (1998), 17, - 2748 - 2758, doi:10.1093/emboj/17.10.2748

    • Abstract - Nine hydrophobic side chains are key determinants of the thermodynamic stability and oligomerization status of tumour suppressor p53 tetramerization domain
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  • Degradation signals for ubiquitin system proteolysis in Saccharomyces cerevisiae FREE

    Tamar Gilon, Orna Chomsky and Richard G. Kulka

    The EMBO Journal (1998), 17, - 2759 - 2766, doi:10.1093/emboj/17.10.2759

    • Abstract - Degradation signals for ubiquitin system proteolysis in : Saccharomyces cerevisiae
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  • Neural Wiskott–Aldrich syndrome protein is implicated in the actin-based motility of Shigella flexneri FREE

    Toshihiko Suzuki, Hiroaki Miki, Tadaomi Takenawa and Chihiro Sasakawa

    The EMBO Journal (1998), 17, - 2767 - 2776, doi:10.1093/emboj/17.10.2767

    • Abstract - Neural Wiskott-Aldrich syndrome protein is implicated in the actin-based motility of : Shigella flexneri
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  • The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes FREE

    Michael E. Greenberg, A.John Iafrate and Jacek Skowronski

    The EMBO Journal (1998), 17, - 2777 - 2789, doi:10.1093/emboj/17.10.2777

    • Abstract - The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes
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  • Functional properties of the ryanodine receptor type 3 (RyR3) Ca²⁺ release channel FREE

    Alois Sonnleitner, Antonio Conti, Federica Bertocchini, Hansgeorg Schindler and Vincenzo Sorrentino

    The EMBO Journal (1998), 17, - 2790 - 2798, doi:10.1093/emboj/17.10.2790

    • Abstract - Functional properties of the ryanodine receptor type 3 (RyR3) Ca: 2+: release channel
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  • Identification of BCAR3 by a random search for genes involved in antiestrogen resistance of human breast cancer cells FREE

    Ton van Agthoven, Thecla L. A. van Agthoven, Anita Dekker, Peter J. van der Spek, Lilian Vreede and Lambert C. J. Dorssers

    The EMBO Journal (1998), 17, - 2799 - 2808, doi:10.1093/emboj/17.10.2799

    • Abstract - Identification of : BCAR: 3 by a random search for genes involved in antiestrogen resistance of human breast cancer cells
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  • Evidence that the RdeA protein is a component of a multistep phosphorelay modulating rate of development in Dictyostelium FREE

    Wen-Tsan Chang, Peter A. Thomason, Julian D. Gross and Peter C. Newell

    The EMBO Journal (1998), 17, - 2809 - 2816, doi:10.1093/emboj/17.10.2809

    • Abstract - Evidence that the RdeA protein is a component of a multistep phosphorelay modulating rate of development in : Dictyostelium
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  • Interferon- expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway FREE

    Mercedes Rincón, Hervé Enslen, Joël Raingeaud, Michael Recht, Tyler Zapton, Michael S-S. Su, Laurie A. Penix, Roger J. Davis and Richard A. Flavell

    The EMBO Journal (1998), 17, - 2817 - 2829, doi:10.1093/emboj/17.10.2817

    • Abstract - Interferon-[gamma] expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway
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  • Sphingosine kinase-mediated Ca²⁺ signalling by G-protein-coupled receptors FREE

    Dagmar Meyer zu Heringdorf, Holger Lass, Regina Alemany, Kai T. Laser, Eva Neumann, Chunyi Zhang, Martina Schmidt, Ursula Rauen, Karl H. Jakobs and Chris J. van Koppen

    The EMBO Journal (1998), 17, - 2830 - 2837, doi:10.1093/emboj/17.10.2830

    • Abstract - Sphingosine kinase-mediated Ca: 2+: signalling by G-protein-coupled receptors
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  • An intersection of the cAMP/PKA and two-component signal transduction systems in Dictyostelium FREE

    Peter A. Thomason, David Traynor, Guy Cavet, Wen-Tsan Chang, Adrian J. Harwood and Robert R. Kay

    The EMBO Journal (1998), 17, - 2838 - 2845, doi:10.1093/emboj/17.10.2838

    • Abstract - An intersection of the cAMP/PKA and two-component signal transduction systems in : Dictyostelium
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  • Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-1 FREE

    Çagatay Günes, Rainer Heuchel, Oleg Georgiev, Karl-Heinz Müller, Peter Lichtlen, Horst Blüthmann, Silvia Marino, Adriano Aguzzi and Walter Schaffner

    The EMBO Journal (1998), 17, - 2846 - 2854, doi:10.1093/emboj/17.10.2846

    • Abstract - Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-1
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  • Cloning and functional characterization of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes FREE

    Petr Jansa, Stephen W. Mason, Urs Hoffmann-Rohrer and Ingrid Grummt

    The EMBO Journal (1998), 17, - 2855 - 2864, doi:10.1093/emboj/17.10.2855

    • Abstract - Cloning and functional characterization of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes
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  • Histone acetylation facilitates RNA polymerase II transcription of the Drosophila hsp26 gene in chromatin FREE

    Karl P. Nightingale, Ralf E. Wellinger, Jose M. Sogo and Peter B. Becker

    The EMBO Journal (1998), 17, - 2865 - 2876, doi:10.1093/emboj/17.10.2865

    • Abstract - Histone acetylation facilitates RNA polymerase II transcription of the : Drosophila hsp26: gene in chromatin
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  • Regulation of crp transcription by oscillation between distinct nucleoprotein complexes FREE

    Gardenia González-Gil, Regine Kahmann and Georgi Muskhelishvili

    The EMBO Journal (1998), 17, - 2877 - 2885, doi:10.1093/emboj/17.10.2877

    • Abstract - Regulation of : crp: transcription by oscillation between distinct nucleoprotein complexes
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  • The acetyltransferase activity of CBP stimulates transcription FREE

    Marian A. Martínez-Balbás, Andrew J. Bannister, Klaus Martin, Philipp Haus-Seuffert, Michael Meisterernst and Tony Kouzarides

    The EMBO Journal (1998), 17, - 2886 - 2893, doi:10.1093/emboj/17.10.2886

    • Abstract - The acetyltransferase activity of CBP stimulates transcription
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  • Induction of type III secretion in Shigella flexneri is associated with differential control of transcription of genes encoding secreted proteins FREE

    Brigitte Demers, Philippe J. Sansonetti and Claude Parsot

    The EMBO Journal (1998), 17, - 2894 - 2903, doi:10.1093/emboj/17.10.2894

    • Abstract - Induction of type III secretion in : Shigella flexneri: is associated with differential control of transcription of genes encoding secreted proteins
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  • Coupling of signal transduction to alternative pre-mRNA splicing by a composite splice regulator FREE

    Harald König, Helmut Ponta and Peter Herrlich

    The EMBO Journal (1998), 17, - 2904 - 2913, doi:10.1093/emboj/17.10.2904

    • Abstract - Coupling of signal transduction to alternative pre-mRNA splicing by a composite splice regulator
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  • A single amino acid substitution in yeast eIF-5A results in mRNA stabilization FREE

    Dorit Zuk and Allan Jacobson

    The EMBO Journal (1998), 17, - 2914 - 2925, doi:10.1093/emboj/17.10.2914

    • Abstract - A single amino acid substitution in yeast eIF-5A results in mRNA stabilization
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  • The DEAH-box protein PRP22 is an ATPase that mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes FREE

    John D.O. Wagner, Eckhard Jankowsky, Mahshid Company, Anna Marie Pyle and John N. Abelson

    The EMBO Journal (1998), 17, - 2926 - 2937, doi:10.1093/emboj/17.10.2926

    • Abstract - The DEAH-box protein PRP22 is an ATPase that mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes
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  • Progression through the spliceosome cycle requires Prp38p function for U4/U6 snRNA dissociation FREE

    Jian Xie, Kristopher Beickman, Elizabeth Otte and Brian C. Rymond

    The EMBO Journal (1998), 17, - 2938 - 2946, doi:10.1093/emboj/17.10.2938

    • Abstract - Progression through the spliceosome cycle requires Prp38p function for U4/U6 snRNA dissociation
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  • The crystal structure of asparaginyl-tRNA synthetase from Thermus thermophilus and its complexes with ATP and asparaginyl-adenylate: the mechanism of discrimination between asparagine and aspartic acid FREE

    Carmen Berthet-Colominas, Laurence Seignovert, Michael Härtlein, Morten Grotli, Stephen Cusack and Reuben Leberman

    The EMBO Journal (1998), 17, - 2947 - 2960, doi:10.1093/emboj/17.10.2947

    • Abstract - The crystal structure of asparaginyl-tRNA synthetase from : Thermus thermophilus: and its complexes with ATP and asparaginyl-adenylate: the mechanism of discrimination between asparagine and aspartic acid
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    • PDF (1,188 KB) - The crystal structure of asparaginyl-tRNA synthetase from : Thermus thermophilus: and its complexes with ATP and asparaginyl-adenylate: the mechanism of discrimination between asparagine and aspartic acid

  • Cell cycle modulation of protein–DNA interactions at a human replication origin FREE

    Gulnara Abdurashidova, Silvano Riva, Giuseppe Biamonti, Mauro Giacca and Arturo Falaschi

    The EMBO Journal (1998), 17, - 2961 - 2969, doi:10.1093/emboj/17.10.2961

    • Abstract - Cell cycle modulation of protein-DNA interactions at a human replication origin
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