Web focus
- The Middle & The End
In 2009 The EMBO Journal review series focuses on different facets of centromere and telomere biology. The specialisation of the centromeres and telomeres, the middle and end regions of eukaryotic chromosomes, respectively, is reflected at numerous levels, such as chromatin, gene regulation, signalling or cellular function. Nine review articles, combined in this web focus series, The Middle & The End, and published in print over several issues of The EMBO Journal, summarise our current understanding of these various aspects of chromosome biology, especially in the light of recent advances, demonstrating parallels as well as differences in the function and organisation of centres and ends.
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Editorial
Top of page-
The middle and the endFREE
The EMBO Journal (2009) 28, - 2143–2144 | doi:10.1038/emboj.2009.191
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Articles
Top of pageSilent chromatin at the middle and ends: lessons from yeasts EMBO Open
The EMBO Journal (2009) 28, - 2149–2161 | doi:10.1038/emboj.2009.185
A 'higher order' of telomere regulation: telomere heterochromatin and telomeric RNAs EMBO Open
The EMBO Journal (2009) 28, - 2323–2336 | doi:10.1038/emboj.2009.197
Focus on the centre: the role of chromatin on the regulation of centromere identity and function EMBO Open
The EMBO Journal (2009) 28, - 2337–2348 | doi:10.1038/emboj.2009.174
TERRA: telomeric repeat-containing RNA EMBO Open
The EMBO Journal (2009) 28, - 2503–2510 | doi:10.1038/emboj.2009.166
The life and miracles of kinetochores EMBO Open
The EMBO Journal (2009) 28, - 2511–2531 | doi:10.1038/emboj.2009.173
A quantitative systems view of the spindle assembly checkpoint EMBO Open
The EMBO Journal (2009) 28, - 2162–2173 | doi:10.1038/emboj.2008.186
Taming the tiger by the tail: modulation of DNA damage responses by telomeres EMBO Open
The EMBO Journal (2009) 28, - 2174–2187 | doi:10.1038/emboj.2009.176
Telomere length regulation: coupling DNA end processing to feedback regulation of telomerase EMBO Open
The EMBO Journal (2009) 28, - 2309–2322 | doi:10.1038/emboj.2009.195
Telomeres and disease EMBO Open
The EMBO Journal (2009) 28, - 2532–2540 | doi:10.1038/emboj.2009.172
