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Dynamic study of the transition from hyaluronan- to integrin-mediated adhesion in chondrocytes

Miriam Cohen, Zvi Kam, Lia Addadi and Benjamin Geiger

The EMBO Journal (2006) 25, 302-311

doi:10.1038/sj.emboj.7600960

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Time-lapse movie of cells expressing paxillin-GFP (green), with the hyaluronan coat labeled by quantum dots (QDs) (red) shows that the appearance of hyaluronan-bound QDs precedes integrin-mediated adhesion.

Imaging of in vitro angiogenesis: Migration of microvascular endothelial cells on Matrigel migrate towards zones of high cell density and network formation.

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