Web focus

Imaging: Welcome to The EMBO Journal's 2006 web focus on imaging. This review series highlights imaging of biological membranes, the dynamics of protein structure, gene expression, cell polarity and cell migration — accompanied by a selection of movies from our archive, linked to the articles in which they originally appeared.

Editorial
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- Let's go to the movies FREE
  Valerie Ferrier
  The EMBO Journal (2006), 25, - 3445 | doi:10.1038/sj.emboj.7601200
  - Full text
  - PDF (35 KB) - Let's go to the movies
Reviews
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- Visualizing polynucleotide polymerase machines at work FREE
  Thomas A Steitz
  The EMBO Journal (2006), 25, - 3458–3468 | doi:10.1038/sj.emboj.7601211
  This review article sums up our current knowledge on the conformational changes that polynucleotide polymerases undergo during the reaction cycle. Movies are provided that allow the reader to "watch" the enzymes in action.
- Gene expression within a dynamic nuclear landscape FREE
  Yaron Shav-Tal, Xavier Darzacq and Robert H Singer
  The EMBO Journal (2006), 25, - 3469–3479 | doi:10.1038/sj.emboj.7601226
  This review article focuses on the application of non-invasive single cell imaging approaches to reveal the dynamic nature of gene expression and elucidate how chromatin, nucleosomes and the transcriptional machinery work together at gene loci and sites of transcription.
- Imaging of cell migration FREE
  Dirk Dormann and Cornelis J Weijer
  The EMBO Journal (2006), 25, - 3480–3493 | doi:10.1038/sj.emboj.7601227
  This review provides a comprehensive overview of the imaging techniques used to analyze cell motility and illustrates how these techniques have been used to characterize chemotaxis in dictyostelium and cell migration in the chick embryo.
- Dynamics in the plasma membrane: how to combine fluidity and order FREE
  Didier Marguet, Pierre-François Lenne, Hervé Rigneault and Hai-Tao He
  The EMBO Journal (2006), 25, - 3446–3457 | doi:10.1038/sj.emboj.7601204
  Marguet and colleagues provide a detailed account of the physicochemical aspects of membrane dynamics, the imaging technologies available for its investigation and the impact of lateral diffusion on signal transduction.
  >
See also
Top of page
- Modeling the early stages of vascular network assembly
  
  Guido Serini, Davide Ambrosi, Enrico Giraudo, Andrea Gamba, Luigi Prezios and Federico Bussolino
  The EMBO Journal (2003), 22, - 1771–1779 | doi:10.1093/emboj/cdg176
- The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport
  Simon L. Bullock, Daniel Zicha and David Ish-Horowicz
  The EMBO Journal (2003), 22, - 2484–2494 | doi:10.1093/emboj/cdg230
- Direct imaging of lateral movements of AMPA receptors inside synapses
  Catherine Tardin, Laurent Cognet, Cécile Bats, Brahim Lounis and Daniel Choquet
  The EMBO Journal (2003), 22, - 4656–4665 | doi:10.1093/emboj/cdg463
- Prickle and Strabismus form a functional complex to generate a correct axis during planar cell polarity signaling
  Andreas Jenny, Rachel S Darken, Paul A Wilson and Marek Mlodzik
  The EMBO Journal (2003), 22, - 4409–4420 | doi:10.1093/emboj/cdg424
- Mechanism controlling perpendicular alignment of the spindle to the axis of cell division in fission yeast
  Yannick Gachet, Sylvie Tournier, Jonathan B A Millar and Jeremy S Hyams
  The EMBO Journal (2004), 23, - 1289–1300 | doi:10.1038/sj.emboj.7600156
- DIP (mDia interacting protein) is a key molecule regulating Rho and Rac in a Src-dependent manner
  Wenxiang Meng, Mitsuko Numazaki, Kumiko Takeuchi, Yoshiari Uchibori, Yuhko Ando-Akatsuka, Makoto Tominaga and Tomoko Tominaga
  The EMBO Journal (2004), 23 | - 760–771, doi:10.1038/sj.emboj.7600095
- Phosphorylation of BCL-2 regulates ER Ca2+ homeostasis and apoptosis
  Michael C Bassik, Luca Scorrano, Scott A Oakes, Tullio Pozzan and Stanley J Korsmeyer
  The EMBO Journal (2004), 23, - 1207–1216 | doi:10.1038/sj.emboj.7600104
- Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation
  Anika Steffen, Klemens Rottner, Julia Ehinger, Metello Innocenti, Giorgio Scita, Jürgen Wehland and Theresia E B Stradal
  The EMBO Journal (2004), 23, - 749–759 | doi:10.1038/sj.emboj.7600084
- Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis
  Marc Germain, Jaigi P Mathai, Heidi M McBride and Gordon C Shore
  The EMBO Journal (2005), 24, - 1546–1556 | doi:10.1038/sj.emboj.7600592
- TI-VAMP/VAMP7 is required for optimal phagocytosis of opsonised particles in macrophages
  Virginie Braun, Vincent Fraisier, Graça Raposo, Ilse Hurbain, Jean-Baptiste Sibarita, Philippe Chavrier, Thierry Galli and Florence Niedergang
  The EMBO Journal (2004), 23 | - 4166–4176, doi:10.1038/sj.emboj.7600427
- A novel mechanism of nuclear envelope break-down in a fungus: nuclear migration strips off the envelope
  Anne Straube, Isabella Weber and Gero Steinberg
  The EMBO Journal (2005), 24, - 1674–1685 | doi:10.1038/sj.emboj.7600644
- Rab11-FIP3 and FIP4 interact with Arf6 and the Exocyst to control membrane traffic in cytokinesis
  Andrew B Fielding, Eric Schonteich, Johanne Matheson, Gayle Wilson, Xinzi Yu, Gilles R X Hickson, Sweta Srivastava, Stephen A Baldwin, Rytis Prekeris and Gwyn W Gould
  The EMBO Journal (2005), 24, - 3389–3399 | doi:10.1038/sj.emboj.7600803
- Multistep and multimode cortical anchoring of tea1p at cell tips in fission yeast
  Hilary A Snaith, Itaru Samejima and Kenneth E Sawin
  The EMBO Journal (2005), 24, - 3690–3699 | doi:10.1038/sj.emboj.7600838
- Ca2+ spikes in the flagellum control chemotactic behavior of sperm
  Martin Böhmer, Qui Van, Ingo Weyand, Volker Hagen, Michael Beyermann, Midori Matsumoto, Motonori Hoshi, Eilo Hildebrand and Ulrich Benjamin Kaupp
  The EMBO Journal (2005), 24, - 2741–2752 | doi:10.1038/sj.emboj.7600744
- The Bud14p-Glc7p complex functions as a cortical regulator of dynein in budding yeast
  Michèle Knaus, Elisabetta Cameroni, Ivo Pedruzzi, Kelly Tatchell, Claudio De Virgilio and Matthias Peter
  The EMBO Journal (2005), 24, - 3000–3011 | doi:10.1038/sj.emboj.7600783
- TRPM7, a novel regulator of actomyosin contractility and cell adhesion
  Michèle Knaus, Elisabetta Cameroni, Ivo Pedruzzi, Kelly Tatchell, Claudio De Virgilio and Matthias Peter
  The EMBO Journal (2006), 25, - 290–301 | doi:10.1038/sj.emboj.7600931
- Unstable microtubule capture at kinetochores depleted of the centromere-associated protein CENP-F
  Pascale Bomont, Paul Maddox, Jagesh V Shah, Arshad B Desai and Don W Cleveland
  The EMBO Journal (2005), 24, - 3927–3939 | doi:10.1038/sj.emboj.7600848
- Dynamic study of the transition from hyaluronan- to integrin-mediated adhesion in chondrocytes
  Miriam Cohen, Zvi Kam, Lia Addadi and Benjamin Geiger
  The EMBO Journal (2006), 25, - 302–311 | doi:10.1038/sj.emboj.7600960
- The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time
  Shin-ichiro Hiraga, E Douglas Robertson and Anne D Donaldson
  The EMBO Journal (2006), 25, - 1505–1514 | doi:10.1038/sj.emboj.7601038
- Seeing is understanding: Improvements in computer software and hardware are revolutionizing three-dimensional imaging in biology
  Holger Breithaupt
  EMBO reports (2006), 7, - 467–470 | doi:10.1038/sj.embor.7400695

Web focus

Editorial

Let's go to the movies FREE

Reviews

Visualizing polynucleotide polymerase machines at work FREE

Gene expression within a dynamic nuclear landscape FREE

Imaging of cell migration FREE

Dynamics in the plasma membrane: how to combine fluidity and order FREE

See also

Modeling the early stages of vascular network assembly

The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport

Direct imaging of lateral movements of AMPA receptors inside synapses

Prickle and Strabismus form a functional complex to generate a correct axis during planar cell polarity signaling

Mechanism controlling perpendicular alignment of the spindle to the axis of cell division in fission yeast

DIP (mDia interacting protein) is a key molecule regulating Rho and Rac in a Src-dependent manner

Phosphorylation of BCL-2 regulates ER Ca2+ homeostasis and apoptosis

Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation

Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis

TI-VAMP/VAMP7 is required for optimal phagocytosis of opsonised particles in macrophages

A novel mechanism of nuclear envelope break-down in a fungus: nuclear migration strips off the envelope

Rab11-FIP3 and FIP4 interact with Arf6 and the Exocyst to control membrane traffic in cytokinesis

Multistep and multimode cortical anchoring of tea1p at cell tips in fission yeast

Ca2+ spikes in the flagellum control chemotactic behavior of sperm

The Bud14p-Glc7p complex functions as a cortical regulator of dynein in budding yeast

TRPM7, a novel regulator of actomyosin contractility and cell adhesion

Unstable microtubule capture at kinetochores depleted of the centromere-associated protein CENP-F

Dynamic study of the transition from hyaluronan- to integrin-mediated adhesion in chondrocytes

The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time

Seeing is understanding: Improvements in computer software and hardware are revolutionizing three-dimensional imaging in biology

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