Welcome to The EMBO Journal web focus on imaging
- recently published Reviews on imaging of biological membranes, the dynamics of protein structure, gene expression, cell polarity and cell migration, together with a selection of movies from our archive linked to the article in which they originally appeared.
Editorial
Let's go to the movies
Valerie Ferrier
doi: 10.1038/sj.emboj.7601200
The EMBO Journal 25, 3445 (2006)
Reviews
Visualizing polynucleotide polymerase machines at work
Thomas A Steitz
doi: 10.1038/sj.emboj.7601211
The EMBO Journal 25, 3458-3468 (2006)
This review article sums up our current knowledge on the conformational changes that polynucleotide polymerases undergo during the reaction cycle. Movies are provided that allow the reader to "watch" the enzymes in action.
Gene expression within a dynamic nuclear landscape
Yaron Shav-Tal, Xavier Darzacq and Robert H Singer
doi: 10.1038/sj.emboj.7601226
The EMBO Journal 25, 3469-3479 (2006)
This review article focuses on the application of non-invasive single cell imaging approaches to reveal the dynamic nature of gene expression and elucidate how chromatin, nucleosomes and the transcriptional machinery work together at gene loci and sites of transcription.
Imaging of cell migration
Dirk Dormann and Cornelis J Weijer
doi: 10.1038/sj.emboj.7601227
The EMBO Journal 25, 3480-3493 (2006)
This review provides a comprehensive overview of the imaging techniques used to analyze cell motility and illustrates how these techniques have been used to characterize chemotaxis in dictyostelium and cell migration in the chick embryo.
Dynamics in the plasma membrane - How to combine fluidity and order?
Didier Marguet, Pierre-François Lenne, Hervé Rigneault and Hai-Tao He
doi: 10.1038/sj.emboj.7601204
The EMBO Journal 25, 3446-3457 (2006)
Marguet and colleagues provide a detailed account of the physicochemical aspects of membrane dynamics, the imaging technologies available for its investigation and the impact of lateral diffusion on signal transduction.
See also
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Modeling the early stages of vascular network assemblyGuido Serini, Davide Ambrosi, Enrico Giraudo, Andrea Gamba, Luigi Preziosi, Federico Bussolino doi: 10.1093/emboj/cdg176 The EMBO Journal 22, 1771-1779 (2003) |
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The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transportSimon L. Bullock, Daniel Zicha, David Ish-Horowicz doi: 10.1093/emboj/cdg230 The EMBO Journal 22, 2484-2494 (2003) |
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Direct imaging of lateral movements of AMPA receptors inside synapsesCatherine Tardin, Laurent Cognet, Cécile Bats, Brahim Lounis, Daniel Choquet doi: doi: 10.1093/emboj/cdg463 The EMBO Journal 22, 4656-4665 (2003) |
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Prickle and Strabismus form a functional complex to generate a correct axis during planar cell polarity signalingAndreas Jenny, Rachel S Darken, Paul A Wilson, Marek Mlodzik doi: 10.1093/emboj/cdg424 The EMBO Journal 22, 4409-4420 (2003) |
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Mechanism controlling perpendicular alignment of the spindle to the axis of cell division in fission yeastYannick Gachet, Sylvie Tournier, Jonathan B A Millar, Jeremy S Hyams doi: 10.1038/sj.emboj.7600156 The EMBO Journal 23, 1289-1300 (2004) |
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DIP (mDia interacting protein) is a key molecule regulating Rho and Rac in a Src-dependent mannerWenxiang Meng, Mitsuko Numazaki, Kumiko Takeuchi, Yoshiari Uchibori, Yuhko Ando-Akatsuka, Makoto Tominaga, Tomoko Tominaga doi: 10.1038/sj.emboj.7600095 The EMBO Journal 23, 760-771 (2004) |
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Phosphorylation of BCL-2 regulates ER Ca2+ homeostasis and apoptosisMichael C Bassik, Luca Scorrano, Scott A Oakes, Tullio Pozzan, Stanley J Korsmeyer doi: 10.1038/sj.emboj.7600104 The EMBO Journal 23, 1207-1216 (2004) |
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Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formationAnika Steffen, Klemens Rottner, Julia Ehinger, Metello Innocenti, Giorgio Scita, Jürgen Wehland, Theresia E B Stradal doi: 10.1038/sj.emboj.7600084 The EMBO Journal 23, 749-759 (2004) |
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Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosisMarc Germain, Jaigi P Mathai, Heidi M McBride, Gordon C Shore doi: 10.1038/sj.emboj.7600592 The EMBO Journal 24, 1546-1556 (2005) |
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TI-VAMP/VAMP7 is required for optimal phagocytosis of opsonised particles in macrophagesVirginie Braun, Vincent Fraisier, Graça Raposo, Ilse Hurbain, Jean-Baptiste Sibarita, Philippe Chavrier, Thierry Galli, Florence Niedergang doi: 10.1038/sj.emboj.7600427 The EMBO Journal 23, 4166-4176 (2004) |
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A novel mechanism of nuclear envelope break-down in a fungus: nuclear migration strips off the envelopeAnne Straube, Isabella Weber, Gero Steinberg doi: 10.1038/sj.emboj.7600644 The EMBO Journal 24, 1674-1685 (2005) |
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Rab11-FIP3 and FIP4 interact with Arf6 and the Exocyst to control membrane traffic in cytokinesisAndrew B Fielding, Eric Schonteich, Johanne Matheson, Gayle Wilson, Xinzi Yu, Gilles R X Hickson, Sweta Srivastava, Stephen A Baldwin, Rytis Prekeris, Gwyn W Gould doi: 10.1038/sj.emboj.7600803 The EMBO Journal 24, 3389-3399 (2005) |
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Multistep and multimode cortical anchoring of tea1p at cell tips in fission yeastHilary A Snaith, Itaru Samejima, Kenneth E Sawin doi: 10.1038/sj.emboj.7600838 The EMBO Journal 24, 3690-3699 (2005) |
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Ca2+ spikes in the flagellum control chemotactic behavior of spermMartin Böhmer, Qui Van, Ingo Weyand, Volker Hagen, Michael Beyermann, Midori Matsumoto, Motonori Hoshi, Eilo Hildebrand, Ulrich Benjamin Kaupp doi: 10.1038/sj.emboj.7600744 The EMBO Journal 24, 2741-2752 (2005) |
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The Bud14p-Glc7p complex functions as a cortical regulator of dynein in budding yeastMichèle Knaus, Elisabetta Cameroni, Ivo Pedruzzi, Kelly Tatchell, Claudio De Virgilio, Matthias Peter doi: 10.1038/sj.emboj.7600783 The EMBO Journal 24, 3000-3011 (2005) |
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TRPM7, a novel regulator of actomyosin contractility and cell adhesionKristopher Clark, Michiel Langeslag, Bart van Leeuwen, Leonie Ran, Alexey G Ryazanov, Carl G Figdor, Wouter H Moolenaar, Kees Jalink, Frank N van Leeuwen doi: 10.1038/sj.emboj.7600931 The EMBO Journal 25, 290-301 (2006) |
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Unstable microtubule capture at kinetochores depleted of the centromere-associated protein CENP-FPascale Bomont, Paul Maddox, Jagesh V Shah, Arshad B Desai, Don W Cleveland doi: 10.1038/sj.emboj.7600848 The EMBO Journal 24, 3927-3939 (2005) |
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Dynamic study of the transition from hyaluronan- to integrin-mediated adhesion in chondrocytesMiriam Cohen, Zvi Kam, Lia Addadi, Benjamin Geiger doi: 10.1038/sj.emboj.7600960 The EMBO Journal 25, 302-311 (2006) |
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The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication timeShin-ichiro Hiraga, E Douglas Robertson, Anne D Donaldson doi: 10.1093/emboj/cdg589 The EMBO Journal 25, 1505-1514 (2006) |
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Seeing is understanding: Improvements in computer software and hardware are revolutionizing three-dimensional imaging in biologyHolger Breithaupt doi: 10.1038/sj.embor.7400695 EMBO reports 7, 467-470 (2006) |
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