Archive: Signal Transduction

Archive type: Issues; : current viewSubject categories; Article categories

Signal Transduction from: 2009 Signal Transduction; 2008 Signal Transduction; 2007 Signal Transduction; 2006 Signal Transduction; 2005 Signal Transduction; 2004 Signal Transduction; 2003 Signal Transduction; 2002 Signal Transduction

| Signal Transduction
- SnoN functions as a tumour suppressor by inducing premature senescence
  Deng Pan, Qingwei Zhu and Kunxin Luo
  The EMBO Journal (2009), 28, - 3500 - 3513, doi:10.1038/emboj.2009.250
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  - Signal Transduction | Molecular Biology of Disease
- Participation of Tom1L1 in EGF-stimulated endocytosis of EGF receptor FREE
  Ning Sheng Liu, Li Shen Loo, Eva Loh, Li-Fong Seet and Wanjin Hong
  The EMBO Journal (2009), 28, - 3485 - 3499, doi:10.1038/emboj.2009.282
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  - Membranes and Transport | Signal Transduction
- Structural basis of phosphodiesterase 6 inhibition by the C-terminal region of the -subunit
  Brandy Barren, Lokesh Gakhar, Hakim Muradov, Kimberly K Boyd, S Ramaswamy and Nikolai O Artemyev
  The EMBO Journal (2009), 28, - 3613 - 3622, doi:10.1038/emboj.2009.284
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  - Signal Transduction | Structural Biology
- The structure of an integrin/talin complex reveals the basis of inside-out signal transduction
  Nicholas J Anthis, Kate L Wegener, Feng Ye, Chungho Kim, Benjamin T Goult, Edward D Lowe, Ioannis Vakonakis, Neil Bate, David R Critchley, Mark H Ginsberg and Iain D Campbell
  The EMBO Journal (2009), 28, - 3623 - 3632, doi:10.1038/emboj.2009.287
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  - Signal Transduction | Structural Biology
- Synapse formation regulated by protein tyrosine phosphatase receptor T through interaction with cell adhesion molecules and Fyn
  So-Hee Lim, Seok-Kyu Kwon, Myung Kyu Lee, Jeonghee Moon, Dae Gwin Jeong, Eunha Park, Seung Jun Kim, Byung Chul Park, Sang Chul Lee, Seong-Eon Ryu, Dae-Yeul Yu, Bong Hyun Chung, Eunjoon Kim, Pyung-Keun Myung and Jae-Ran Lee
  The EMBO Journal (2009), 28, - 3564 - 3578, doi:10.1038/emboj.2009.289
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  - Signal Transduction | Neuroscience
- 4E-BP1 is a target of Smad4 essential for TGF-mediated inhibition of cell proliferation
  Rania Azar, Amandine Alard, Christiane Susini, Corinne Bousquet and Stéphane Pyronnet
  The EMBO Journal (2009), 28, - 3514 - 3522, doi:10.1038/emboj.2009.291
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  - Signal Transduction | Molecular Biology of Disease
- Ligand-regulated oligomerization of ₂-adrenoceptors in a model lipid bilayer FREE
  Juan José Fung, Xavier Deupi, Leonardo Pardo, Xiao Jie Yao, Gisselle A Velez-Ruiz, Brian T DeVree, Roger K Sunahara and Brian K Kobilka
  The EMBO Journal (2009), 28, - 3315 - 3328, doi:10.1038/emboj.2009.267
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  - Signal Transduction
- The kinase TNIK is an essential activator of Wnt target genes
  Tokameh Mahmoudi, Vivian S W Li, Ser Sue Ng, Nadia Taouatas, Robert G J Vries, Shabaz Mohammed, Albert J Heck and Hans Clevers
  The EMBO Journal (2009), 28, - 3329 - 3340, doi:10.1038/emboj.2009.285
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  - Signal Transduction | Chromatin and Transcription
- Zfh1 promotes survival of a peripheral glia subtype by antagonizing a Jun N-terminal kinase-dependent apoptotic pathway
  David Ohayon, Alexandre Pattyn, Stephanie Venteo, Jean Valmier, Patrick Carroll and Alain Garces
  The EMBO Journal (2009), 28, - 3228 - 3243, doi:10.1038/emboj.2009.247
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  - Signal Transduction | Differentiation and Death
- Emerging common themes in regulation of PIKKs and PI3Ks FREE
  Harri Lempiäinen and Thanos D Halazonetis
  The EMBO Journal (2009), 28, - 3067 - 3073, doi:10.1038/emboj.2009.281
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  - Signal Transduction | Genome Stability and Dynamics
- Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal 7 nicotinic acetylcholine receptor
  Ryan E Hibbs, Gerlind Sulzenbacher, Jianxin Shi, Todd T Talley, Sandrine Conrod, William R Kem, Palmer Taylor, Pascale Marchot and Yves Bourne
  The EMBO Journal (2009), 28, - 3040 - 3051, doi:10.1038/emboj.2009.227
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  - Signal Transduction | Structural Biology
- A non-redundant role for MKP5 in limiting ROS production and preventing LPS-induced vascular injury
  Feng Qian, Jing Deng, Ni Cheng, Emily J Welch, Yongliang Zhang, Asrar B Malik, Richard A Flavell, Chen Dong and Richard D Ye
  The EMBO Journal (2009), 28, - 2896 - 2907, doi:10.1038/emboj.2009.234
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  - Signal Transduction | Immunology
- Neurogranin enhances synaptic strength through its interaction with calmodulin FREE
  Ling Zhong, Tiffani Cherry, Christine E Bies, Matthew A Florence and Nashaat Z Gerges
  The EMBO Journal (2009), 28, - 3027 - 3039, doi:10.1038/emboj.2009.236
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  - Signal Transduction | Neuroscience
- FoxM1, a critical regulator of oxidative stress during oncogenesis FREE
  Hyun Jung Park, Janai R Carr, Zebin Wang, Veronique Nogueira, Nissim Hay, Angela L Tyner, Lester F Lau, Robert H Costa and Pradip Raychaudhuri
  The EMBO Journal (2009), 28, - 2908 - 2918, doi:10.1038/emboj.2009.239
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  - Signal Transduction | Molecular Biology of Disease
- NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain
  E Laplantine, E Fontan, J Chiaravalli, T Lopez, G Lakisic, M Véron, F Agou and Alain Israël
  The EMBO Journal (2009), 28, - 2885 - 2895, doi:10.1038/emboj.2009.241
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  - Signal Transduction
- The making of a chloroplast FREE
  Mark T Waters and Jane A Langdale
  The EMBO Journal (2009), 28, - 2861 - 2873, doi:10.1038/emboj.2009.264
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  - Signal Transduction | Plant Biology
- The structural basis of Arf effector specificity: the crystal structure of ARF6 in a complex with JIP4
  Tatiana Isabet, Guillaume Montagnac, Karine Regazzoni, Bertrand Raynal, Fatima El Khadali, Patrick England, Michel Franco, Philippe Chavrier, Anne Houdusse and Julie Ménétrey
  The EMBO Journal (2009), 28, - 2835 - 2845, doi:10.1038/emboj.2009.209
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  - Signal Transduction | Structural Biology
- -arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT₄ receptor signalling
  Gaël Barthet, Gaëlle Carrat, Elizabeth Cassier, Breann Barker, Florence Gaven, Marion Pillot, Bérénice Framery, Lucie P Pellissier, Julie Augier, Dong Soo Kang, Sylvie Claeysen, Eric Reiter, Jean-Louis Banères, Jeffrey L Benovic, Philippe Marin, Joël Bockaert and Aline Dumuis
  The EMBO Journal (2009), 28, - 2706 - 2718, doi:10.1038/emboj.2009.215
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  - Signal Transduction
- Regulation of heterochromatin remodelling and myogenin expression during muscle differentiation by FAK interaction with MBD2
  Shi-Wen Luo, Chun Zhang, Bin Zhang, Chang-Hoon Kim, Yuan-Zheng Qiu, Quan-Sheng Du, Lin Mei and Wen-Cheng Xiong
  The EMBO Journal (2009), 28, - 2568 - 2582, doi:10.1038/emboj.2009.178
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  - Signal Transduction | Differentiation and Death
- The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding
  Jennifer N Cash, Carlis A Rejon, Alexandra C McPherron, Daniel J Bernard and Thomas B Thompson
  The EMBO Journal (2009), 28, - 2662 - 2676, doi:10.1038/emboj.2009.205
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  - Signal Transduction | Structural Biology
- Structural basis of GDP release and gating in G protein coupled Fe²⁺ transport
  Amy Guilfoyle, Megan J Maher, Mikaela Rapp, Ronald Clarke, Stephen Harrop and Mika Jormakka
  The EMBO Journal (2009), 28, - 2677 - 2685, doi:10.1038/emboj.2009.208
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  - Signal Transduction | Structural Biology
- Numb regulates cell–cell adhesion and polarity in response to tyrosine kinase signalling FREE
  Zezhou Wang, Shelley Sandiford, Chenggang Wu and Shawn Shun-Cheng Li
  The EMBO Journal (2009), 28, - 2360 - 2373, doi:10.1038/emboj.2009.190
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  - Cell and Tissue Architecture | Signal Transduction
- Crosstalk between GABA_B and mGlu1a receptors reveals new insight into GPCR signal integration
  Marie-Laure Rives, Claire Vol, Yugo Fukazawa, Norbert Tinel, Eric Trinquet, Mohammed Akli Ayoub, Ryuichi Shigemoto, Jean-Philippe Pin and Laurent Prézeau
  The EMBO Journal (2009), 28, - 2195 - 2208, doi:10.1038/emboj.2009.177
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  - Signal Transduction | Neuroscience
- Mechanisms of regulation of RNA polymerase III-dependent transcription by TORC1
  Yuehua Wei, Chi Kwan Tsang and X F Steven Zheng
  The EMBO Journal (2009), 28, - 2220 - 2230, doi:10.1038/emboj.2009.179
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  - Signal Transduction | Chromatin and Transcription
- A quantitative systems view of the spindle assembly checkpoint FREE
  Andrea Ciliberto and Jagesh V Shah
  The EMBO Journal (2009), 28, - 2162 - 2173, doi:10.1038/emboj.2009.186
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  - Signal Transduction | Cell Cycle
- Mal connects TLR2 to PI3Kinase activation and phagocyte polarization
  S Santos-Sierra, S D Deshmukh, J Kalnitski, P Küenzi, M P Wymann, D T Golenbock and Philipp Henneke
  The EMBO Journal (2009), 28, - 2018 - 2027, doi:10.1038/emboj.2009.158
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  - Signal Transduction
- TAK1 is an essential regulator of BMP signalling in cartilage FREE
  Jae-Hyuck Shim, Matthew B Greenblatt, Min Xie, Michael D Schneider, Weiguo Zou, Bo Zhai, Steven Gygi and Laurie H Glimcher
  The EMBO Journal (2009), 28, - 2028 - 2041, doi:10.1038/emboj.2009.162
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  - Signal Transduction | Development
- Dynamics of macrophage polarization reveal new mechanism to inhibit IL-1 release through pyrophosphates FREE
  Pablo Pelegrin and Annmarie Surprenant
  The EMBO Journal (2009), 28, - 2114 - 2127, doi:10.1038/emboj.2009.163
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  - Signal Transduction | Immunology
- JNK signalling modulates intestinal homeostasis and tumourigenesis in mice
  Rocio Sancho, Abdolrahman S Nateri, Amaya Garcia de Vinuesa, Cristina Aguilera, Emma Nye, Bradley Spencer-Dene and Axel Behrens
  The EMBO Journal (2009), 28, - 1843 - 1854, doi:10.1038/emboj.2009.153
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  - Signal Transduction | Molecular Biology of Disease
- The deubiquitinases USP33 and USP20 coordinate ₂ adrenergic receptor recycling and resensitization
  Magali Berthouze, Vidya Venkataramanan, Yi Li and Sudha K Shenoy
  The EMBO Journal (2009), 28, - 1684 - 1696, doi:10.1038/emboj.2009.128
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  - Signal Transduction | Proteins
- Mitochondrial apoptosis induced by BH3-only molecules in the exclusive presence of endoplasmic reticular Bak
  Martina Klee, Kathrin Pallauf, Sonia Alcalá, Aarne Fleischer and Felipe X Pimentel-Muiños
  The EMBO Journal (2009), 28, - 1757 - 1768, doi:10.1038/emboj.2009.90
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  - Signal Transduction | Differentiation and Death
- Novel crosstalk to BMP signalling: cGMP-dependent kinase I modulates BMP receptor and Smad activity
  Raphaela Schwappacher, Jörg Weiske, Eva Heining, Verena Ezerski, Barak Marom, Yoav I Henis, Otmar Huber and Petra Knaus
  The EMBO Journal (2009), 28, - 1537 - 1550, doi:10.1038/emboj.2009.103
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  - Signal Transduction
- Auto-phosphorylation of a voltage-gated K⁺ channel controls non-associative learning
  Shi-Qing Cai, Yi Wang, Ki Ho Park, Xin Tong, Zui Pan and Federico Sesti
  The EMBO Journal (2009), 28, - 1601 - 1611, doi:10.1038/emboj.2009.112
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  - Signal Transduction | Neuroscience
- MAPKAP kinase MK2 maintains self-renewal capacity of haematopoietic stem cells
  Jessica Schwermann, Chozhavendan Rathinam, Maria Schubert, Stefanie Schumacher, Fatih Noyan, Haruhiko Koseki, Alexey Kotlyarov, Christoph Klein and Matthias Gaestel
  The EMBO Journal (2009), 28, - 1392 - 1406, doi:10.1038/emboj.2009.100
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  - Signal Transduction | Differentiation and Death
- Glycosylation defects activate filamentous growth Kss1 MAPK and inhibit osmoregulatory Hog1 MAPK
  Hui-Yu Yang, Kazuo Tatebayashi, Katsuyoshi Yamamoto and Haruo Saito
  The EMBO Journal (2009), 28, - 1380 - 1391, doi:10.1038/emboj.2009.104
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  - Signal Transduction
- The mechano-activated K⁺ channels TRAAK and TREK-1 control both warm and cold perception
  Jacques Noël, Katharina Zimmermann, Jérome Busserolles, Emanuel Deval, Abdelkrim Alloui, Sylvie Diochot, Nicolas Guy, Marc Borsotto, Peter Reeh, Alain Eschalier and Michel Lazdunski
  The EMBO Journal (2009), 28, - 1308 - 1318, doi:10.1038/emboj.2009.57
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  - Signal Transduction | Neuroscience
- A constitutively active GPCR governs morphogenic transitions in Cryptococcus neoformans
  Yen-Ping Hsueh, Chaoyang Xue and Joseph Heitman
  The EMBO Journal (2009), 28, - 1220 - 1233, doi:10.1038/emboj.2009.68
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  - Signal Transduction
- CtBP1/BARS is an activator of phospholipase D1 necessary for agonist-induced macropinocytosis FREE
  Yuki Haga, Noriko Miwa, Saleem Jahangeer, Taro Okada and Shun-ichi Nakamura
  The EMBO Journal (2009), 28, - 1197 - 1207, doi:10.1038/emboj.2009.78
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  - Membranes and Transport | Signal Transduction
- Synaptic removal of diacylglycerol by DGK and PSD-95 regulates dendritic spine maintenance
  Karam Kim, Jinhee Yang, Xiao-Ping Zhong, Myoung-Hwan Kim, Yun Sook Kim, Hyun Woo Lee, Seungnam Han, Jeonghoon Choi, Kihoon Han, Jinsoo Seo, Stephen M Prescott, Matthew K Topham, Yong Chul Bae, Gary Koretzky, Se-Young Choi and Eunjoon Kim
  The EMBO Journal (2009), 28, - 1170 - 1179, doi:10.1038/emboj.2009.44
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  - Signal Transduction | Neuroscience
- Acid sphingomyelinase activity triggers microparticle release from glial cells FREE
  Fabio Bianco, Cristiana Perrotta, Luisa Novellino, Maura Francolini, Loredana Riganti, Elisabetta Menna, Laura Saglietti, Edward H Schuchman, Roberto Furlan, Emilio Clementi, Michela Matteoli and Claudia Verderio
  The EMBO Journal (2009), 28, - 1043 - 1054, doi:10.1038/emboj.2009.45
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  - Signal Transduction | Neuroscience
- Genome-wide analysis of light-inducible responses reveals hierarchical light signalling in Neurospora
  Chen-Hui Chen, Carol S Ringelberg, Robert H Gross, Jay C Dunlap and Jennifer J Loros
  The EMBO Journal (2009), 28, - 1029 - 1042, doi:10.1038/emboj.2009.54
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  - Signal Transduction | Chromatin and Transcription | Genomic and Computational Biology
- Mimicking Ndc80 phosphorylation triggers spindle assembly checkpoint signalling
  Stefan Kemmler, Manuel Stach, Maria Knapp, Jennifer Ortiz, Jens Pfannstiel, Thomas Ruppert and Johannes Lechner
  The EMBO Journal (2009), 28, - 1099 - 1110, doi:10.1038/emboj.2009.62
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  - Signal Transduction | Cell Cycle
- ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis
  Takayuki Iriyama, Kohsuke Takeda, Hiromi Nakamura, Yoshifumi Morimoto, Takumi Kuroiwa, Junya Mizukami, Tsuyoshi Umeda, Takuya Noguchi, Isao Naguro, Hideki Nishitoh, Kaoru Saegusa, Kei Tobiume, Toshiki Homma, Yutaka Shimada, Hitoshi Tsuda, Satoshi Aiko, Issei Imoto, Johji Inazawa, Kazuhiro Chida, Yoshimasa Kamei, Shiro Kozuma, Yuji Taketani, Atsushi Matsuzawa and Hidenori Ichijo
  The EMBO Journal (2009), 28, - 843 - 853, doi:10.1038/emboj.2009.32
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  - Signal Transduction | Molecular Biology of Disease
- Transcription and signalling pathways involved in BCR–ABL-mediated misregulation of 24p3 and 24p3R
  Zhi Sheng, Shu-Zong Wang and Michael R Green
  The EMBO Journal (2009), 28, - 866 - 876, doi:10.1038/emboj.2009.35
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  - Signal Transduction | Chromatin and Transcription
- Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5–type I receptor specificity
  Alexander Kotzsch, Joachim Nickel, Axel Seher, Walter Sebald and Thomas D Müller
  The EMBO Journal (2009), 28, - 937 - 947, doi:10.1038/emboj.2009.37
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  - Signal Transduction | Structural Biology
- Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint
  Mylavarapu V S Sivaram, Thomas L Wadzinski, Sambra D Redick, Tapas Manna and Stephen J Doxsey
  The EMBO Journal (2009), 28, - 902 - 914, doi:10.1038/emboj.2009.38
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  - Signal Transduction | Cell Cycle
- TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells
  Griselda Herrero-Martín, Maria Høyer-Hansen, Celina García-García, Claudia Fumarola, Thomas Farkas, Abelardo López-Rivas and Marja Jäättelä
  The EMBO Journal (2009), 28, - 677 - 685, doi:10.1038/emboj.2009.8
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  - Signal Transduction | Differentiation and Death
- The Axin1 scaffold protein promotes formation of a degradation complex for c-Myc
  Hugh K Arnold, Xiaoli Zhang, Colin J Daniel, Deanne Tibbitts, Julie Escamilla-Powers, Amy Farrell, Sara Tokarz, Charlie Morgan and Rosalie C Sears
  The EMBO Journal (2009), 28, - 500 - 512, doi:10.1038/emboj.2008.279
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  - Signal Transduction | Proteins
- The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-B signalling
  Noula Shembade, Kislay Parvatiyar, Nicole S Harhaj and Edward W Harhaj
  The EMBO Journal (2009), 28, - 513 - 522, doi:10.1038/emboj.2008.285
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  - Signal Transduction | Differentiation and Death
- Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF
  Deo Prakash Pandey, Rosamaria Lappano, Lidia Albanito, Antonio Madeo, Marcello Maggiolini and Didier Picard
  The EMBO Journal (2009), 28, - 523 - 532, doi:10.1038/emboj.2008.304
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  - Signal Transduction | Molecular Biology of Disease
- Spatially and kinetically resolved changes in the conformational dynamics of the Hsp90 chaperone machine
  Christian Graf, Marta Stankiewicz, Günter Kramer and Matthias P Mayer
  The EMBO Journal (2009), 28, - 602 - 613, doi:10.1038/emboj.2008.306
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  - Signal Transduction | Structural Biology
- The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK–ERK pathway to late endosomes
  Shigeyki Nada, Akihiro Hondo, Atsuko Kasai, Masato Koike, Kazunobu Saito, Yasuo Uchiyama and Masato Okada
  The EMBO Journal (2009), 28, - 477 - 489, doi:10.1038/emboj.2008.308
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  - Membranes and Transport | Signal Transduction
- Making a grade: Sonic Hedgehog signalling and the control of neural cell fate FREE
  James Briscoe
  The EMBO Journal (2009), 28, - 457 - 465, doi:10.1038/emboj.2009.12
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  - Signal Transduction | Development
- Interaction of COP1 and UVR8 regulates UV-B-induced photomorphogenesis and stress acclimation in Arabidopsis
  Jean-Jacques Favory, Agnieszka Stec, Henriette Gruber, Luca Rizzini, Attila Oravecz, Markus Funk, Andreas Albert, Catherine Cloix, Gareth I Jenkins, Edward J Oakeley, Harald K Seidlitz, Ferenc Nagy and Roman Ulm
  The EMBO Journal (2009), 28, - 591 - 601, doi:10.1038/emboj.2009.4
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  - Signal Transduction | Plant Biology
- Accumulation of raft lipids in T-cell plasma membrane domains engaged in TCR signalling
  Tobias Zech, Christer S Ejsing, Katharina Gaus, Ben de Wet, Andrej Shevchenko, Kai Simons and Thomas Harder
  The EMBO Journal (2009), 28, - 466 - 476, doi:10.1038/emboj.2009.6
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  - Membranes and Transport | Signal Transduction
- Regulation of Notch and Wingless signalling by phyllopod, a transcriptional target of the EGFR pathway
  Raghavendra Nagaraj and Utpal Banerjee
  The EMBO Journal (2009), 28, - 337 - 346, doi:10.1038/emboj.2008.286
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  - Signal Transduction | Development
- Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7
  Surabhi Dangi-Garimella, Jieun Yun, Eva M Eves, Martin Newman, Stefan J Erkeland, Scott M Hammond, Andy J Minn and Marsha Rich Rosner
  The EMBO Journal (2009), 28, - 347 - 358, doi:10.1038/emboj.2008.294
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  - Full text
  - PDF (277 KB) -
  - Supplementary information
  Subject Categories:
  - Signal Transduction | Molecular Biology of Disease
- Recruitment of a chromatin remodelling complex by the Hog1 MAP kinase to stress genes FREE
  Glòria Mas, Eulàlia de Nadal, Reinhard Dechant, María Luisa Rodríguez de la Concepción, Colin Logie, Silvia Jimeno-González, Sebastián Chávez, Gustav Ammerer and Francesc Posas
  The EMBO Journal (2009), 28, - 326 - 336, doi:10.1038/emboj.2008.299
  - Abstract -
  - Full text
  - PDF (832 KB) -
  - Supplementary information
  Subject Categories:
  - Signal Transduction | Chromatin and Transcription
- Sall2 is a novel p75NTR-interacting protein that links NGF signalling to cell cycle progression and neurite outgrowth
  Roxana Pincheira, Melinda Baerwald, James D Dunbar and David B Donner
  The EMBO Journal (2009), 28, - 261 - 273, doi:10.1038/emboj.2008.274
  - Abstract -
  - Full text
  - PDF (2,334 KB) -
  - Supplementary information
  Subject Categories:
  - Signal Transduction | Neuroscience
- TGF-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGF switch
  Irwin M Liu, Stephen H Schilling, Kristin A Knouse, Lisa Choy, Rik Derynck and Xiao-Fan Wang
  The EMBO Journal (2008), 28, - 88 - 98, doi:10.1038/emboj.2008.266
  - Abstract -
  - Full text
  - PDF (924 KB) -
  - Supplementary information
  Subject Categories:
  - Signal Transduction | Molecular Biology of Disease
- Cancer induction by restriction of oncogene expression to the stem cell compartment FREE
  María Pérez-Caro, César Cobaleda, Inés González-Herrero, Carolina Vicente-Dueñas, Camino Bermejo-Rodríguez, Margarita Sánchez-Beato, Alberto Orfao, Belén Pintado, Teresa Flores, Manuel Sánchez-Martín, Rafael Jiménez, Miguel A Piris and Isidro Sánchez-García
  The EMBO Journal (2009), 28, - 8 - 20, doi:10.1038/emboj.2008.253
  - Abstract -
  - Full text
  - PDF (2,189 KB) -
  - Supplementary information
  Subject Categories:
  - Signal Transduction | Molecular Biology of Disease

Archive: Signal Transduction

| Signal Transduction

SnoN functions as a tumour suppressor by inducing premature senescence

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Participation of Tom1L1 in EGF-stimulated endocytosis of EGF receptor FREE

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Structural basis of phosphodiesterase 6 inhibition by the C-terminal region of the -subunit

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The structure of an integrin/talin complex reveals the basis of inside-out signal transduction

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Synapse formation regulated by protein tyrosine phosphatase receptor T through interaction with cell adhesion molecules and Fyn

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4E-BP1 is a target of Smad4 essential for TGF-mediated inhibition of cell proliferation

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Ligand-regulated oligomerization of 2-adrenoceptors in a model lipid bilayer FREE

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The kinase TNIK is an essential activator of Wnt target genes

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Zfh1 promotes survival of a peripheral glia subtype by antagonizing a Jun N-terminal kinase-dependent apoptotic pathway

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Emerging common themes in regulation of PIKKs and PI3Ks FREE

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Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal 7 nicotinic acetylcholine receptor

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A non-redundant role for MKP5 in limiting ROS production and preventing LPS-induced vascular injury

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Neurogranin enhances synaptic strength through its interaction with calmodulin FREE

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FoxM1, a critical regulator of oxidative stress during oncogenesis FREE

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NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain

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The making of a chloroplast FREE

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The structural basis of Arf effector specificity: the crystal structure of ARF6 in a complex with JIP4

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-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling

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Regulation of heterochromatin remodelling and myogenin expression during muscle differentiation by FAK interaction with MBD2

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The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding

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Structural basis of GDP release and gating in G protein coupled Fe2+ transport

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Numb regulates cell–cell adhesion and polarity in response to tyrosine kinase signalling FREE

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Crosstalk between GABAB and mGlu1a receptors reveals new insight into GPCR signal integration

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Mechanisms of regulation of RNA polymerase III-dependent transcription by TORC1

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A quantitative systems view of the spindle assembly checkpoint FREE

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Mal connects TLR2 to PI3Kinase activation and phagocyte polarization

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TAK1 is an essential regulator of BMP signalling in cartilage FREE

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Dynamics of macrophage polarization reveal new mechanism to inhibit IL-1 release through pyrophosphates FREE

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JNK signalling modulates intestinal homeostasis and tumourigenesis in mice

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The deubiquitinases USP33 and USP20 coordinate 2 adrenergic receptor recycling and resensitization

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Mitochondrial apoptosis induced by BH3-only molecules in the exclusive presence of endoplasmic reticular Bak

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Novel crosstalk to BMP signalling: cGMP-dependent kinase I modulates BMP receptor and Smad activity

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Auto-phosphorylation of a voltage-gated K+ channel controls non-associative learning

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MAPKAP kinase MK2 maintains self-renewal capacity of haematopoietic stem cells

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Glycosylation defects activate filamentous growth Kss1 MAPK and inhibit osmoregulatory Hog1 MAPK

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The mechano-activated K+ channels TRAAK and TREK-1 control both warm and cold perception

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A constitutively active GPCR governs morphogenic transitions in Cryptococcus neoformans

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CtBP1/BARS is an activator of phospholipase D1 necessary for agonist-induced macropinocytosis FREE

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Synaptic removal of diacylglycerol by DGK and PSD-95 regulates dendritic spine maintenance

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Ligand-regulated oligomerization of ₂-adrenoceptors in a model lipid bilayer FREE

-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT₄ receptor signalling

Structural basis of GDP release and gating in G protein coupled Fe²⁺ transport

Crosstalk between GABA_B and mGlu1a receptors reveals new insight into GPCR signal integration

The deubiquitinases USP33 and USP20 coordinate ₂ adrenergic receptor recycling and resensitization

Auto-phosphorylation of a voltage-gated K⁺ channel controls non-associative learning

The mechano-activated K⁺ channels TRAAK and TREK-1 control both warm and cold perception