Archive: Articles 1999

Archive type: Issues; Subject categories; : current viewArticle categories

Articles from

2009

2008

2007

2006

2005

2004

2003

2002

2001

2000

1999

1998

1997

December 1999 | Articles
- Crystal structure of calpain reveals the structural basis for Ca²⁺-dependent protease activity and a novel mode of enzyme activation FREE
  Christopher M. Hosfield, John S. Elce, Peter L. Davies and Zongchao Jia
  The EMBO Journal (1999), 18, - 6880 - 6889, doi:10.1093/emboj/18.24.6880
  - Abstract - Crystal structure of calpain reveals the structural basis for Ca: 2+: -dependent protease activity and a novel mode of enzyme activation
  - Full text
  - PDF (1,132 KB) - Crystal structure of calpain reveals the structural basis for Ca: 2+: -dependent protease activity and a novel mode of enzyme activation
- Crystal structure of the ARF-GAP domain and ankyrin repeats of PYK2-associated protein FREE
  Valsan Mandiyan, Julian Andreev, Joseph Schlessinger and Stevan R. Hubbard
  The EMBO Journal (1999), 18, - 6890 - 6898, doi:10.1093/emboj/18.24.6890
  - Abstract - Crystal structure of the ARF-GAP domain and ankyrin repeats of PYK2-associated protein [beta]
  - Full text
  - PDF (1,444 KB) - Crystal structure of the ARF-GAP domain and ankyrin repeats of PYK2-associated protein [beta]
- Crystal structure of UvrB, a DNA helicase adapted for nucleotide excision repair FREE
  Karsten Theis, Paul J. Chen, Milan Skorvaga, Bennett Van Houten and Caroline Kisker
  The EMBO Journal (1999), 18, - 6899 - 6907, doi:10.1093/emboj/18.24.6899
  - Abstract - Crystal structure of UvrB, a DNA helicase adapted for nucleotide excision repair
  - Full text
  - PDF (794 KB) - Crystal structure of UvrB, a DNA helicase adapted for nucleotide excision repair
- The monomeric homing endonuclease PI-SceI has two catalytic centres for cleavage of the two strands of its DNA substrate FREE
  Frauke Christ, Sylvia Schoettler, Wolfgang Wende, Shawn Steuer, Alfred Pingoud and Vera Pingoud
  The EMBO Journal (1999), 18, - 6908 - 6916, doi:10.1093/emboj/18.24.6908
  - Abstract - The monomeric homing endonuclease PI-: Sce: I has two catalytic centres for cleavage of the two strands of its DNA substrate
  - Full text
  - PDF (430 KB) - The monomeric homing endonuclease PI-: Sce: I has two catalytic centres for cleavage of the two strands of its DNA substrate
- Functionally different GPI proteins are organized in different domains on the neuronal surface FREE
  Nathalie Madore, Karen L. Smith, Catriona H. Graham, Angela Jen, Ken Brady, Susan Hall and Roger Morris
  The EMBO Journal (1999), 18, - 6917 - 6926, doi:10.1093/emboj/18.24.6917
  - Abstract - Functionally different GPI proteins are organized in different domains on the neuronal surface
  - Full text
  - PDF (1,342 KB) - Functionally different GPI proteins are organized in different domains on the neuronal surface
- Effects of macromolecular crowding on protein folding and aggregation FREE
  Bert van den Berg, R.John Ellis and Christopher M. Dobson
  The EMBO Journal (1999), 18, - 6927 - 6933, doi:10.1093/emboj/18.24.6927
  - Abstract - Effects of macromolecular crowding on protein folding and aggregation
  - Full text
  - PDF (111 KB) - Effects of macromolecular crowding on protein folding and aggregation
- Identification of thermolabile Escherichia coli proteins: prevention and reversion of aggregation by DnaK and ClpB FREE
  Axel Mogk, Toshifumi Tomoyasu, Pierre Goloubinoff, Stefan Rüdiger, Daniel Röder, Hanno Langen and Bernd Bukau
  The EMBO Journal (1999), 18, - 6934 - 6949, doi:10.1093/emboj/18.24.6934
  - Abstract - Identification of thermolabile : Escherichia coli: proteins: prevention and reversion of aggregation by DnaK and ClpB
  - Full text
  - PDF (1,203 KB) - Identification of thermolabile : Escherichia coli: proteins: prevention and reversion of aggregation by DnaK and ClpB
- Recruitment of the protein tyrosine phosphatase CSW by DOS is an essential step during signaling by the Sevenless receptor tyrosine kinase FREE
  Ronald Herbst, Xiaolong Zhang, Jun Qin and Michael A. Simon
  The EMBO Journal (1999), 18, - 6950 - 6961, doi:10.1093/emboj/18.24.6950
  - Abstract - Recruitment of the protein tyrosine phosphatase CSW by DOS is an essential step during signaling by the Sevenless receptor tyrosine kinase
  - Full text
  - PDF (1,370 KB) - Recruitment of the protein tyrosine phosphatase CSW by DOS is an essential step during signaling by the Sevenless receptor tyrosine kinase
- Ectodomain shedding of TGF- and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades FREE
  Huizhou Fan and Rik Derynck
  The EMBO Journal (1999), 18, - 6962 - 6972, doi:10.1093/emboj/18.24.6962
  - Abstract - Ectodomain shedding of TGF-[alpha] and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades
  - Full text
  - PDF (548 KB) - Ectodomain shedding of TGF-[alpha] and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades
- Cell type-specific activation of mitogen-activated protein kinases by CpG-DNA controls interleukin-12 release from antigen-presenting cells FREE
  Hans Häcker, Harald Mischak, Georg Häcker, Sema Eser, Norbert Prenzel, Axel Ullrich and Hermann Wagner
  The EMBO Journal (1999), 18, - 6973 - 6982, doi:10.1093/emboj/18.24.6973
  - Abstract - Cell type-specific activation of mitogen-activated protein kinases by CpG-DNA controls interleukin-12 release from antigen-presenting cells
  - Full text
  - PDF (359 KB) - Cell type-specific activation of mitogen-activated protein kinases by CpG-DNA controls interleukin-12 release from antigen-presenting cells
- Direct inhibition of G₁ cdk kinase activity by MyoD promotes myoblast cell cycle withdrawal and terminal differentiation FREE
  Jian-Min Zhang, Xiaohang Zhao, Qin Wei and Bruce M. Paterson
  The EMBO Journal (1999), 18, - 6983 - 6993, doi:10.1093/emboj/18.24.6983
  - Abstract - Direct inhibition of G: 1: cdk kinase activity by MyoD promotes myoblast cell cycle withdrawal and terminal differentiation
  - Full text
  - PDF (759 KB) - Direct inhibition of G: 1: cdk kinase activity by MyoD promotes myoblast cell cycle withdrawal and terminal differentiation
- Interaction between developmental and cell cycle regulators is required for morphogenesis in Aspergillus nidulans FREE
  Xiang S. Ye, Sheau-Ling Lee, Tom D. Wolkow, Sarah-Lee McGuire, John E. Hamer, G.Craig Wood and Stephen A. Osmani
  The EMBO Journal (1999), 18, - 6994 - 7001, doi:10.1093/emboj/18.24.6994
  - Abstract - Interaction between developmental and cell cycle regulators is required for morphogenesis in : Aspergillus nidulans
  - Full text
  - PDF (459 KB) - Interaction between developmental and cell cycle regulators is required for morphogenesis in : Aspergillus nidulans
- Serine 15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2 FREE
  Nicolas Dumaz and David W. Meek
  The EMBO Journal (1999), 18, - 7002 - 7010, doi:10.1093/emboj/18.24.7002
  - Abstract - Serine 15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2
  - Full text
  - PDF (430 KB) - Serine 15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2
- RAR-independent RXR signaling induces t(15;17) leukemia cell maturation FREE
  Gérard Benoit, Lucia Altucci, Maria Flexor, Sandrine Ruchaud, Johan Lillehaug, Wolfgang Raffelsberger, Hinrich Gronemeyer and Michel Lanotte
  The EMBO Journal (1999), 18, - 7011 - 7018, doi:10.1093/emboj/18.24.7011
  - Abstract - RAR-independent RXR signaling induces t(15;17) leukemia cell maturation
  - Full text
  - PDF (811 KB) - RAR-independent RXR signaling induces t(15;17) leukemia cell maturation
- Mga, a dual-specificity transcription factor that interacts with Max and contains a T-domain DNA-binding motif FREE
  Peter J. Hurlin, Eirìkur Steingrìmsson, Neal G. Copeland, Nancy A. Jenkins and Robert N. Eisenman
  The EMBO Journal (1999), 18, - 7019 - 7028, doi:10.1093/emboj/18.24.7019
  - Abstract - Mga, a dual-specificity transcription factor that interacts with Max and contains a T-domain DNA-binding motif
  - Full text
  - PDF (743 KB) - Mga, a dual-specificity transcription factor that interacts with Max and contains a T-domain DNA-binding motif
- Osa associates with the Brahma chromatin remodeling complex and promotes the activation of some target genes FREE
  Russell T. Collins, Takako Furukawa, Naoko Tanese and Jessica E. Treisman
  The EMBO Journal (1999), 18, - 7029 - 7040, doi:10.1093/emboj/18.24.7029
  - Abstract - Osa associates with the Brahma chromatin remodeling complex and promotes the activation of some target genes
  - Full text
  - PDF (1,161 KB) - Osa associates with the Brahma chromatin remodeling complex and promotes the activation of some target genes
- SIR repression of a yeast heat shock gene: UAS and TATA footprints persist within heterochromatin FREE
  Edward A. Sekinger and David S. Gross
  The EMBO Journal (1999), 18, - 7041 - 7055, doi:10.1093/emboj/18.24.7041
  - Abstract - SIR: repression of a yeast heat shock gene: UAS and TATA footprints persist within heterochromatin
  - Full text
  - PDF (1,137 KB) - SIR: repression of a yeast heat shock gene: UAS and TATA footprints persist within heterochromatin
- C to U editing of the anticodon of imported mitochondrial tRNA^Trp allows decoding of the UGA stop codon in Leishmania tarentolae FREE
  Juan D. Alfonzo, Valerie Blanc, Antonio M. Estévez, Mary Anne T. Rubio and Larry Simpson
  The EMBO Journal (1999), 18, - 7056 - 7062, doi:10.1093/emboj/18.24.7056
  - Abstract - C to U editing of the anticodon of imported mitochondrial tRNA: Trp: allows decoding of the UGA stop codon in : Leishmania tarentolae
  - Full text
  - PDF (348 KB) - C to U editing of the anticodon of imported mitochondrial tRNA: Trp: allows decoding of the UGA stop codon in : Leishmania tarentolae
- The Escherichia coli trmE (mnmE) gene, involved in tRNA modification, codes for an evolutionarily conserved GTPase with unusual biochemical properties FREE
  Hugo Cabedo, Fernando Macián, Magda Villarroya, Juan C. Escudero, Marta Martínez-Vicente, Erwin Knecht and M. Eugenia Armengod
  The EMBO Journal (1999), 18, - 7063 - 7076, doi:10.1093/emboj/18.24.7063
  - Abstract - The : Escherichia coli trmE: (: mnmE: ) gene, involved in tRNA modification, codes for an evolutionarily conserved GTPase with unusual biochemical properties
  - Full text
  - PDF (394 KB) - The : Escherichia coli trmE: (: mnmE: ) gene, involved in tRNA modification, codes for an evolutionarily conserved GTPase with unusual biochemical properties
- Aphid transmission of cauliflower mosaic virus requires the viral PIII protein FREE
  Véronique Leh, Emmanuel Jacquot, Angèle Geldreich, Thomas Hermann, Denis Leclerc, Martine Cerutti, Pierre Yot, Mario Keller and Stéphane Blanc
  The EMBO Journal (1999), 18, - 7077 - 7085, doi:10.1093/emboj/18.24.7077
  - Abstract - Aphid transmission of cauliflower mosaic virus requires the viral PIII protein
  - Full text
  - PDF (873 KB) - Aphid transmission of cauliflower mosaic virus requires the viral PIII protein
- Crystal structure of a thwarted mismatch glycosylase DNA repair complex FREE
  Tracey E. Barrett, Orlando D. Schärer, Renos Savva, Tom Brown, Josef Jiricny, Gregory L. Verdine and Laurence H. Pearl
  The EMBO Journal (1999), 18, - 6599 - 6609, doi:10.1093/emboj/18.23.6599
  - Abstract -
  - Full text
  - PDF (1,765 KB) -
- The structure of a chromosomal high mobility group protein–DNA complex reveals sequence-neutral mechanisms important for non-sequence-specific DNA recognition FREE
  Frank V. Murphy IV, Robert M. Sweet and Mair E.A. Churchill
  The EMBO Journal (1999), 18, - 6610 - 6618, doi:10.1093/emboj/18.23.6610
  - Abstract -
  - Full text
  - PDF (819 KB) -
- Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells FREE
  Yuko Yamaguchi-Iwai, Eiichiro Sonoda, Masao S. Sasaki, Ciaran Morrison, Tokuko Haraguchi, Yasushi Hiraoka, Yukiko M. Yamashita, Takashi Yagi, Minoru Takata, Carolyn Price, Naoki Kakazu and Shunichi Takeda
  The EMBO Journal (1999), 18, - 6619 - 6629, doi:10.1093/emboj/18.23.6619
  - Abstract -
  - Full text
  - PDF (553 KB) -
- Quantitative comparison of DNA looping in vitro and in vivo: chromatin increases effective DNA flexibility at short distances FREE
  Leonie Ringrose, Sophie Chabanis, Pierre-Olivier Angrand, Catherine Woodroofe and A.Francis Stewart
  The EMBO Journal (1999), 18, - 6630 - 6641, doi:10.1093/emboj/18.23.6630
  - Abstract -
  - Full text
  - PDF (685 KB) -
- Replication cycle-coordinated change of the adenine nucleotide-bound forms of DnaA protein in Escherichia coli FREE
  Kenji Kurokawa, Satoshi Nishida, Akiko Emoto, Kazuhisa Sekimizu and Tsutomu Katayama
  The EMBO Journal (1999), 18, - 6642 - 6652, doi:10.1093/emboj/18.23.6642
  - Abstract -
  - Full text
  - PDF (372 KB) -
- Solution structure of the methyl-CpG-binding domain of the methylation-dependent transcriptional repressor MBD1 FREE
  Izuru Ohki, Nobuya Shimotake, Naoyuki Fujita, Mitsuyoshi Nakao and Masahiro Shirakawa
  The EMBO Journal (1999), 18, - 6653 - 6661, doi:10.1093/emboj/18.23.6653
  - Abstract -
  - Full text
  - PDF (971 KB) -
- A new regulatory domain on the TATA-binding protein FREE
  Yong Cang, David T. Auble and Gregory Prelich
  The EMBO Journal (1999), 18, - 6662 - 6671, doi:10.1093/emboj/18.23.6662
  - Abstract -
  - Full text
  - PDF (683 KB) -
- Gal83 mediates the interaction of the Snf1 kinase complex with the transcription activator Sip4 FREE
  Olivier Vincent and Marian Carlson
  The EMBO Journal (1999), 18, - 6672 - 6681, doi:10.1093/emboj/18.23.6672
  - Abstract -
  - Full text
  - PDF (381 KB) -
- An N-terminal nuclear export signal is required for the nucleocytoplasmic shuttling of IB FREE
  Connie Johnson, Daniel Van Antwerp and Thomas J. Hope
  The EMBO Journal (1999), 18, - 6682 - 6693, doi:10.1093/emboj/18.23.6682
  - Abstract -
  - Full text
  - PDF (1,097 KB) -
- NF-B activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase FREE
  Joel L. Pomerantz and David Baltimore
  The EMBO Journal (1999), 18, - 6694 - 6704, doi:10.1093/emboj/18.23.6694
  - Abstract -
  - Full text
  - PDF (551 KB) -
- Kinetic dissection of fundamental processes of eukaryotic translation initiation in vitro FREE
  Jon R. Lorsch and Daniel Herschlag
  The EMBO Journal (1999), 18, - 6705 - 6717, doi:10.1093/emboj/18.23.6705
  - Abstract -
  - Full text
  - PDF (282 KB) -
- Calreticulin functions in vitro as a molecular chaperone for both glycosylated and non-glycosylated proteins FREE
  Yoshiro Saito, Yoshito Ihara, Michael R. Leach, Myrna F. Cohen-Doyle and David B. Williams
  The EMBO Journal (1999), 18, - 6718 - 6729, doi:10.1093/emboj/18.23.6718
  - Abstract -
  - Full text
  - PDF (577 KB) -
- MtGimC, a novel archaeal chaperone related to the eukaryotic chaperonin cofactor GimC/prefoldin FREE
  Michel R. Leroux, Marcus Fändrich, Daniel Klunker, Katja Siegers, Andrei N. Lupas, James R. Brown, Elmar Schiebel, Christopher M. Dobson and F.Ulrich Hartl
  The EMBO Journal (1999), 18, - 6730 - 6743, doi:10.1093/emboj/18.23.6730
  - Abstract -
  - Full text
  - PDF (1,032 KB) -
- Hsp26: a temperature-regulated chaperone FREE
  Martin Haslbeck, Stefan Walke, Thusnelda Stromer, Monika Ehrnsperger, Helen E. White, Shaoxia Chen, Helen R. Saibil and Johannes Buchner
  The EMBO Journal (1999), 18, - 6744 - 6751, doi:10.1093/emboj/18.23.6744
  - Abstract -
  - Full text
  - PDF (545 KB) -
- Two activities of cofilin, severing and accelerating directional depolymerization of actin filaments, are affected differentially by mutations around the actin-binding helix FREE
  Kenji Moriyama and Ichiro Yahara
  The EMBO Journal (1999), 18, - 6752 - 6761, doi:10.1093/emboj/18.23.6752
  - Abstract -
  - Full text
  - PDF (607 KB) -
- Interaction of agrin with laminin requires a coiled-coil conformation of the agrin-binding site within the laminin 1 chain FREE
  Richard A. Kammerer, Therese Schulthess, Ruth Landwehr, Beat Schumacher, Ariel Lustig, Peter D. Yurchenco, Markus A. Ruegg, Jürgen Engel and Alain J. Denzer
  The EMBO Journal (1999), 18, - 6762 - 6770, doi:10.1093/emboj/18.23.6762
  - Abstract -
  - Full text
  - PDF (378 KB) -
- Host cyclophilin A mediates HIV-1 attachment to target cells via heparans FREE
  Andrew C.S. Saphire, Michael D. Bobardt and Philippe A. Gallay
  The EMBO Journal (1999), 18, - 6771 - 6785, doi:10.1093/emboj/18.23.6771
  - Abstract -
  - Full text
  - PDF (349 KB) -
- Dynein motor regulation stabilizes interphase microtubule arrays and determines centrosome position FREE
  Michael P. Koonce, Jana Köhler, Ralph Neujahr, Jean-Marc Schwartz, Irina Tikhonenko and Günther Gerisch
  The EMBO Journal (1999), 18, - 6786 - 6792, doi:10.1093/emboj/18.23.6786
  - Abstract -
  - Full text
  - PDF (769 KB) -
- Yersinia enterocolitica type III secretion–translocationsystem: channel formation by secreted Yops FREE
  Florence Tardy, Fabrice Homblé, Cécile Neyt, Ruddy Wattiez, Guy R. Cornelis, Jean-Marie Ruysschaert and Véronique Cabiaux
  The EMBO Journal (1999), 18, - 6793 - 6799, doi:10.1093/emboj/18.23.6793
  - Abstract -
  - Full text
  - PDF (216 KB) -
- Cysteine-scanning mutagenesis provides no evidence for the extracellular accessibility of the nucleotide-binding domains of the multidrug resistance transporter P-glycoprotein FREE
  Emma J. Blott, Christopher F. Higgins and Kenneth J. Linton
  The EMBO Journal (1999), 18, - 6800 - 6808, doi:10.1093/emboj/18.23.6800
  - Abstract -
  - Full text
  - PDF (713 KB) -
- Redox signalling in the chloroplast: structure of oxidized pea fructose-1,6-bisphosphate phosphatase FREE
  Mohammed Chiadmi, Alda Navaza, Myroslawa Miginiac-Maslow, Jean-Pierre Jacquot and Jacqueline Cherfils
  The EMBO Journal (1999), 18, - 6809 - 6815, doi:10.1093/emboj/18.23.6809
  - Abstract -
  - Full text
  - PDF (682 KB) -
- Carbohydrate deficient glycoprotein syndrome type IV: deficiency of dolichyl-P-Man:Man₅ GlcNAc₂-PP-dolichyl mannosyltransferase FREE
  Christian Körner, Roland Knauer, Ulrich Stephani, Thorsten Marquardt, Ludwig Lehle and Kurt von Figura
  The EMBO Journal (1999), 18, - 6816 - 6822, doi:10.1093/emboj/18.23.6816
  - Abstract -
  - Full text
  - PDF (402 KB) -
- Crystal structure of the surfactin synthetase-activating enzyme Sfp: a prototype of the 4'-phosphopantetheinyl transferase superfamily FREE
  Klaus Reuter, Mohammad R. Mofid, Mohamed A. Marahiel and Ralf Ficner
  The EMBO Journal (1999), 18, - 6823 - 6831, doi:10.1093/emboj/18.23.6823
  - Abstract -
  - Full text
  - PDF (914 KB) -
- The E2–E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain FREE
  Youming Xie and Alexander Varshavsky
  The EMBO Journal (1999), 18, - 6832 - 6844, doi:10.1093/emboj/18.23.6832
  - Abstract -
  - Full text
  - PDF (596 KB) -
- Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation FREE
  Dmitry V. Bulavin, Shiichi Saito, M. Christine Hollander, Kazuyasu Sakaguchi, Carl W. Anderson, Ettore Appella and Albert J. Fornace Jr
  The EMBO Journal (1999), 18, - 6845 - 6854, doi:10.1093/emboj/18.23.6845
  - Abstract -
  - Full text
  - PDF (629 KB) -
- A single amino acid alteration (101L) introduced into murine PrP dramatically alters incubation time of transmissible spongiform encephalopathy FREE
  Jean C. Manson, Elizabeth Jamieson, Herbert Baybutt, Nadia L. Tuzi, Rona Barron, Irene McConnell, Robert Somerville, James Ironside, Robert Will, Man-Sun Sy, David W. Melton, James Hope and Christopher Bostock
  The EMBO Journal (1999), 18, - 6855 - 6864, doi:10.1093/emboj/18.23.6855
  - Abstract -
  - Full text
  - PDF (1,131 KB) -

Archive: Articles 1999

December 1999 | Articles

Crystal structure of calpain reveals the structural basis for Ca2+-dependent protease activity and a novel mode of enzyme activation FREE

Crystal structure of the ARF-GAP domain and ankyrin repeats of PYK2-associated protein FREE

Crystal structure of UvrB, a DNA helicase adapted for nucleotide excision repair FREE

The monomeric homing endonuclease PI-SceI has two catalytic centres for cleavage of the two strands of its DNA substrate FREE

Functionally different GPI proteins are organized in different domains on the neuronal surface FREE

Effects of macromolecular crowding on protein folding and aggregation FREE

Identification of thermolabile Escherichia coli proteins: prevention and reversion of aggregation by DnaK and ClpB FREE

Recruitment of the protein tyrosine phosphatase CSW by DOS is an essential step during signaling by the Sevenless receptor tyrosine kinase FREE

Ectodomain shedding of TGF- and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades FREE

Cell type-specific activation of mitogen-activated protein kinases by CpG-DNA controls interleukin-12 release from antigen-presenting cells FREE

Direct inhibition of G1 cdk kinase activity by MyoD promotes myoblast cell cycle withdrawal and terminal differentiation FREE

Interaction between developmental and cell cycle regulators is required for morphogenesis in Aspergillus nidulans FREE

Serine 15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2 FREE

RAR-independent RXR signaling induces t(15;17) leukemia cell maturation FREE

Mga, a dual-specificity transcription factor that interacts with Max and contains a T-domain DNA-binding motif FREE

Osa associates with the Brahma chromatin remodeling complex and promotes the activation of some target genes FREE

SIR repression of a yeast heat shock gene: UAS and TATA footprints persist within heterochromatin FREE

C to U editing of the anticodon of imported mitochondrial tRNATrp allows decoding of the UGA stop codon in Leishmania tarentolae FREE

The Escherichia coli trmE (mnmE) gene, involved in tRNA modification, codes for an evolutionarily conserved GTPase with unusual biochemical properties FREE

Aphid transmission of cauliflower mosaic virus requires the viral PIII protein FREE

Crystal structure of a thwarted mismatch glycosylase DNA repair complex FREE

The structure of a chromosomal high mobility group protein–DNA complex reveals sequence-neutral mechanisms important for non-sequence-specific DNA recognition FREE

Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells FREE

Quantitative comparison of DNA looping in vitro and in vivo: chromatin increases effective DNA flexibility at short distances FREE

Replication cycle-coordinated change of the adenine nucleotide-bound forms of DnaA protein in Escherichia coli FREE

Solution structure of the methyl-CpG-binding domain of the methylation-dependent transcriptional repressor MBD1 FREE

A new regulatory domain on the TATA-binding protein FREE

Gal83 mediates the interaction of the Snf1 kinase complex with the transcription activator Sip4 FREE

An N-terminal nuclear export signal is required for the nucleocytoplasmic shuttling of IB FREE

NF-B activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase FREE

Kinetic dissection of fundamental processes of eukaryotic translation initiation in vitro FREE

Calreticulin functions in vitro as a molecular chaperone for both glycosylated and non-glycosylated proteins FREE

MtGimC, a novel archaeal chaperone related to the eukaryotic chaperonin cofactor GimC/prefoldin FREE

Hsp26: a temperature-regulated chaperone FREE

Two activities of cofilin, severing and accelerating directional depolymerization of actin filaments, are affected differentially by mutations around the actin-binding helix FREE

Interaction of agrin with laminin requires a coiled-coil conformation of the agrin-binding site within the laminin 1 chain FREE

Host cyclophilin A mediates HIV-1 attachment to target cells via heparans FREE

Dynein motor regulation stabilizes interphase microtubule arrays and determines centrosome position FREE

Yersinia enterocolitica type III secretion–translocationsystem: channel formation by secreted Yops FREE

Cysteine-scanning mutagenesis provides no evidence for the extracellular accessibility of the nucleotide-binding domains of the multidrug resistance transporter P-glycoprotein FREE

Redox signalling in the chloroplast: structure of oxidized pea fructose-1,6-bisphosphate phosphatase FREE

Carbohydrate deficient glycoprotein syndrome type IV: deficiency of dolichyl-P-Man:Man5 GlcNAc2-PP-dolichyl mannosyltransferase FREE

Crystal structure of the surfactin synthetase-activating enzyme Sfp: a prototype of the 4'-phosphopantetheinyl transferase superfamily FREE

The E2–E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain FREE

Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation FREE

A single amino acid alteration (101L) introduced into murine PrP dramatically alters incubation time of transmissible spongiform encephalopathy FREE

Main navigation

Search

The EMBO Journal

Authors and Referees

Customer Service

Journal Services

EMBO Resources

Crystal structure of calpain reveals the structural basis for Ca²⁺-dependent protease activity and a novel mode of enzyme activation FREE

Direct inhibition of G₁ cdk kinase activity by MyoD promotes myoblast cell cycle withdrawal and terminal differentiation FREE

C to U editing of the anticodon of imported mitochondrial tRNA^Trp allows decoding of the UGA stop codon in Leishmania tarentolae FREE

Carbohydrate deficient glycoprotein syndrome type IV: deficiency of dolichyl-P-Man:Man₅ GlcNAc₂-PP-dolichyl mannosyltransferase FREE