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TRANSPARENCY INITIATIVE AT THE EMBO JOURNAL
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In order to make the editorial process more understandable and transparent, the online supplement of all articles published in The EMBO Journal now contains a transcript of reviewer comments, editor's letters, and author responses connected to the respective manuscript. For interesting examples of a constructive review process and/or good discussion, take a look at the Review Process Files for Liu et al., Bhatia et al., Quian et al. or Azar et al.!
You can further find updated statistics on overall timings and manuscript flow in 2008 as well as the results of a new retrospective analysis of the fate of manuscripts submitted to and rejected by The EMBO Journal in 2007.
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Have You Seen…?
Top of pageOncogene and tumour suppressor: the two faces of SnoN
SnoN is known to function as an oncogene and as a repressor of TGFβ/Smad signalling. A study in this issue of The EMBO Journal now reveals that SnoN can also work as a tumour suppressor, independent of its role in Smad signalling.
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AOP Highlights
- Advance online publication
- 19 November 2009
Pretaporter, a Drosophila protein serving as a ligand for Draper in the phagocytosis of apoptotic cells
An important function of phagocytic cells is the specific removal of apoptotic cells during development and tissue homeostasis. This is mediated in part by expression of the cell surface receptor Draper, whose ligand on apoptotic cells however remained unknown. Here, Nakanishi and colleagues now identify Pretaporter as a protein specifically expressed on the surface of apoptotic cells and required for phagocytosis.
Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by NZF domains of TAB2 and TAB3
Polyubiquitin linkage specificity is important in various cellular processes, necessitating strategies for differential read-out by ubiquitin-binding proteins. Shuya Fukai and colleagues now show that TAB2/3, upstream activators of the JNK and NF-κB signalling pathways, employ a single domain to recognize not the linkage itself, but to make distinct contacts with two K63-linked ubiquitins locked into a specific conformation, thus distinguishing it from other modes of linkage-specific recognition.
Advance online publication in full
Web Focus Collections
Top of pageThe Middle & The End
This is a 2009 review series containing nine articles on different aspects of the most distinctive regions of eukaryotic chromosomes, centromeres and telomeres.
Focus on The Middle & The End in full
Quality control in an unreliable world
This 2008 collection of eight review articles highlights different aspects of cellular quality control and their potential relevance for human diseases.
Focus on Quality Control in full
Let's go to the movies
This review series highlights imaging of biological membranes, the dynamics of protein structure, gene expression, cell polarity and cell migration — accompanied by a selection of movies from our archive, linked to the articles in which they originally appeared.
Focus on Imaging in full
Other Publications
Top of pageEMBO Reports
From the organization that brings you The EMBO Journal, EMBO Reports provides sharply focused short papers and review articles in all areas of molecular biology.
science & society
reviews
scientific reports
Molecular Systems Biology
Molecular Systems Biology is an open access online only journal covering all aspects of the rapidly growing and interdisciplinary field of systems biology at the molecular levels.
