European Journal of Human Genetics
SEARCH     advanced search my account e-alerts subscribe register
Journal home
Advance online publication
Current issue
Press releases
For authors
For referees
Contact editorial office
About the journal
About the society
For librarians
Contact Springer Nature
Customer services
Site features
NPG Subject areas
Access material from all our publications in your subject area:
Biotechnology Biotechnology
Cancer Cancer
Chemistry Chemistry
Dentistry Dentistry
Development Development
Drug Discovery Drug Discovery
Earth Sciences Earth Sciences
Evolution & Ecology Evolution & Ecology
Genetics Genetics
Immunology Immunology
Materials Materials Science
Medical Research Medical Research
Microbiology Microbiology
Molecular Cell Biology Molecular Cell Biology
Neuroscience Neuroscience
Pharmacology Pharmacology
Physics Physics
Browse all publications
April 2001, Volume 9, Number 4, Pages 316-318
Table of contents    Previous  Abstract  Next   Article  PDF
Meeting report
3rd International Meeting on Single Nucleotide Polymorphism and Complex Genome Analysis: SNPs: 'Some Notable Progress'
P Scott White1, Pui-Yan Kwok2, Peter Oefner3 and Anthony J Brookes4

1Center for Human Genome Studies and Bioscience Division, Los Alamos National Laboratory, Los Alamos, NM, USA

2Division of Dermatology, Washington University School of Medicine, St. Louis, MO, USA

3Stanford DNA Sequencing & Technology Center, Palo Alto, CA, USA

4Center for Genomics Research, Karolinska Institute, Stockholm, Sweden

Correspondence to: P Scott White, B-N1, Mailstop M888, Genomics, and Center for Human Genome Studies, Bioscience Division, Los Alamos National Laboratory, Los Alamos, NM 87545, USA. Tel: +1 505 665 3860; Fax: +1 505 665 3024; E-mail:


Fervent activities for the collection and exploitation of single nucleotide polymorphism (SNP) data continue, amid concerns about their real utility. The desire to understand complex disease aetiology remains a key driving force for this activity. Recent developments provided a level of cautious optimism not seen in previous International Meetings on Single Nucleotide Polymorphism and Complex Genome Analysis. The 3rd such meeting, held 8-11 September 2000 in Taos, New Mexico, covered research on technologies for SNP scoring, analytical tools for using SNPs to map disease genes, examples from researchers using SNPs for specific disease studies, and databases and tools for facilitating these activities. Studies of human history, and a range of studies upon model organisms were also represented. Whilst the transition from technology oriented work (methods, discovery, etc.) to successful biological application is occurring relatively slowly, a clear trend in this direction is now apparent, and it will surely gain momentum in future months and years. Many fundamental properties of SNPs remain unknown, and many other basic questions are still unanswered, but the field is moving forward on all necessary fronts, promising exciting advances just around the corner. European Journal of Human Genetics (2001) 9, 316-318.


population genetics; variation; SNP genotyping; complex disease

Received 13 November 2000; revised 24 November 2000; accepted 28 November 2000
April 2001, Volume 9, Number 4, Pages 316-318
Table of contents    Previous  Abstract  Next   Article  PDF