FIGURES AND TABLES

Figure 1.

Geographic location of the 10 studied villages on islands of the Eastern Adriatic, Northern and Middle Dalmatia, Croatia.

Figure 2.

Representation, in two-dimensional space, of genetic distances between villages based on allele frequencies at 26 autosomal short tandem repeat (STR) markers. Chord distances²⁰ were computed using the Genetix software, and were represented in two-dimensional space by use of multidimensional scaling analysis using the SPSS 6.0 package. The average proportion of variance in the initial distance matrix accounted for in the two-dimensional plots is 97%.

Figure 3.

Population structure in the 10 Croatian villages analysed based on 26 STR markers. Results from the clustering method implemented by the program STRUCTURE for inferring population structure under the different assumptions about the number of clusters (K=2,...7). In each run, each separate cluster is represented by a colour. Each individual is represented by a line, which is partitioned into coloured segments according to the individual's estimated membership fractions in each of the K clusters. Predefined villages: 1-Banjol, 2-Barbat, 3-Lopar, 4-Rab, 5-S.Draga, 6-Vis, 7-Komiza, 8-Lastovo, 9-Mljet, 10-Susak.

Figure 4.

Number of STR pairs on Xq21-Xp13-21 displaying significant linkage disequilibrium (LD) in the 10 Croatian isolate village samples surveyed and in a sample of similar size consisting of unrelated individuals from an outbred population, the general UK population.

Table 1 - Demographic variables in the 10 villages studied.

Table 2 - Gene diversity and excess homozygosity based on STR markers.