Clinical Case Report

European Journal of Clinical Nutrition (2013) 67, 996–997; doi:10.1038/ejcn.2013.128; published online 17 July 2013

Delirium as a result of vitamin B12 deficiency in a vegetarian female patient

K Mavrommati1 and O Sentissi1

1Department of Mental Health and Psychiatry, University Hospitals of Geneva, Geneva, Switzerland

Correspondence: Dr SEI Othman, Department of Mental health and psychiatry, University Hospitals of Geneva, CAPPI Jonction, 35 Rue des bains, Geneva 1205, Switzerland. E-mail:

Received 27 January 2013; Revised 8 June 2013; Accepted 10 June 2013
Advance online publication 17 July 2013



Vitamin B12 deficiency can manifest with haematological, gastrointestinal and neuropsychiatric signs. The neuropsychiatric symptoms may be concurrent or precede the other symptoms. The reported case is a clinical case of delirium due to vitamin B12 deficiency in a female vegetarian patient. The patient was treated with vitamin B12 supplementation. Initially, it was difficult to diagnose this patient, who presented with delirium that could have been due to multiple causes. The finding underlines the importance of conducting a complete laboratory test panel for delirium, including the blood levels of vitamin B12.


delirium; vitamin B12 deficiency; vegetarian

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