Original Article

European Journal of Clinical Nutrition (2008) 62, 1079–1089; doi:10.1038/sj.ejcn.1602825; published online 30 May 2007

Vitamin D status and health correlates among German adults

B Hintzpeter1, G B M Mensink1, W Thierfelder1, M J Müller2 and C Scheidt-Nave1

  1. 1Department of Epidemiology and Health Reporting, Robert Koch-Institute, Germany
  2. 2Institute of Human Nutrition and Food Science, University of Kiel, Germany

Correspondence: B Hintzpeter, Robert Koch-Institute, Department of Epidemiology and Health Reporting, Seestraße 10, 13353 Berlin, Germany. E-mail: hintzpeterb@rki.de

Received 8 November 2006; Revised 8 March 2007; Accepted 30 April 2007; Published online 30 May 2007.





To analyze vitamin D status based on serum 25-hydroxyvitamin D (25OHD) measurements, its determinants and health correlates in a representative sample of German adults.



A total of 1763 men and 2267 women, 18- to 79-year old, who participated in the representative German National Health Interview and Examination Survey 1998 and the integrated German Nutrition Survey.



The median vitamin D intake from both diet and supplements did not meet the recommended level of 5μg/day, in either men (2.8μg/day) or women (2.3μg/day). Altogether 80.9% of men and 88.5% of women had vitamin D intakes below this level. Moderate (12.5–25nmol/l serum 25OHD levels) and mild (25–50nmol/l) vitamin D deficiency was prevalent in the adult population in Germany, even in younger age groups. Overall, 57% of men and 58% of women had vitamin D levels below 50nmol/l. Among 65- to 79-year-old women, the proportion amounted to 75%, even during the sunnier half of the year. In sex-specific multiple linear regression models, independent determinants of serum 25OHD levels consistently included season, vitamin D intake from both diet and supplements, physical activity and living in a partnership. In addition, age and current menopausal hormone use contributed to the model among women, as opposed to time of day of blood sampling and body mass index (marginally) among men. Significantly lower serum 25OHD levels were observed in women with hypertension, cardiovascular diseases and noninsulin-treated diabetes mellitus as well as in men with insulin-treated diabetes mellitus compared with nonaffected participants.



Vitamin D deficiency is a public health issue in Germany. We identified a number of determinants with potential for primary prevention of vitamin D deficiency. Risk and benefits of preventive actions need to be examined in further studies.


vitamin D, deficiency, serum 25OHD level, epidemiology, population survey, Germany



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