Original Article
European Journal of Clinical Nutrition (2006) 60, 58–61. doi:10.1038/sj.ejcn.1602267; published online 31 August 2005
Adult Home Parenteral Nutrition: a clinical evaluation after a 3-year experience in a Southern European centre
Guarantors: F Pasanisi and F Contaldo.
Contributors: GV, LA, LS, carried out the literature research, designed the study, interpreted the data, conducted the statistical analysis and wrote the paper. MCC, GN, CDC, NR contributed to the design and interpretation of the study and the collection of the study data. FC, FP designed the study and contributed to the writing of the paper. FP supervised the statistical analysis.
G Violante1, L Alfonsi1, L Santarpia1, M C Cillis1, G Negro1, C De Caprio1, N Russo1, F Contaldo1 and F Pasanisi1
1Internal Medicine and Clinical Nutrition, Department of Clinical and Experimental Medicine, Federico II University, Naples, Italy
Correspondence: Dr L Santarpia, Dipartimento di Medicina Clinica e Sperimentale, Università Federico II, Via Pansini, 80131 Napoli, Italy. E-mail: nad2005@unina.it, santarpia@aliceposta.it
Received 20 December 2004; Revised 2 June 2005; Accepted 4 July 2005; Published online 31 August 2005.
Abstract
Aim:
To evaluate the current use of Home Parenteral Nutrition (HPN) in a Southern European region.
Subjects and methods:
A total of 159 (86 m, 73 f) HPN patients, mean age 60.1
14.2 years, BMI 18.83.3 kg/m2, consecutively referred to the Artificial Nutrition outpatient Unit of the Federico II University Hospital in Naples (Italy), from January 2000 to December 2002 and treated for at least 4 weeks. Retrospective evaluation of baseline disease, indications and duration of HPN treatment, type of venous access, complications.
Results:
In all, 140 (88%) were cancer and 19 (12%) noncancer patients. Main indications were carcinosis in 68 for total, and hypophagia/dysphagia in 62 patients for partial/integrative (to oral-enteral nutrition) HPN; mean duration of HPN was 81.45110.86 days of treatment and infection rate 2.89
in the whole population and 2.66 in the 36 patients treated for more than 3 months. No other major complications have been observed.
Conclusion:
HPN is confirmed to be a safe and effective treatment when prescribed and administered by a trained team.
Keywords:
Home Parenteral Nutrition (HPN), indications, complications, safety
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