Summary Review/Temporomandibular Disorders
Evidence-Based Dentistry (2009) 10, 56. doi:10.1038/sj.ebd.6400656
Inconsistent evidence for the use of tricyclic antidepressants in the treatment of temporomandibular joint disorders
Question: Are tricyclic antidepressants effective in the treatment of temporomandibular joint disorders?
Address for correspondence: Professor Cosme Gay Escoda, Centro Médico Teknon, C/ Vilana no 12, 08022 Barcelona, Spain. E-mail: cgay@ub.edu
Aad JJ Zonnenberg1
1Prosthodontist, Santpoort-Noord, The Netherlands
Cascos-Romero J, Vázquez-Delgado E, Vázquez-Rodríguez E, Gay-Escoda C. The use of tricyclic antidepressants in the treatment of temporomandibular joint disorders: systematic review of the literature of the last 20 years. Med Oral Patol Oral Cir Bucal 2009; 14: E3–E7
Abstract
Data sources
Medline and the Cochrane Library were consulted to find evidence in the literature.
Study selection
The English language studies identified were considered and stratified according to the Strength of Recommendation Taxonomy (SORT) criteria.1
Data extraction and synthesis
A qualitative review was conducted.
Results
11 articles were identified, seven of which were reviews.
Conclusions
There is evidence, based on inconsistent or limited-quality patient-oriented data (SORT level B recommendation), for the use of tricyclic antidepressants (TCA) in the treatment of temporomandibular joint disorders (TMD).
