Research & reviews

This month's research & review articles

		Can literature analysis identify innovation drivers in drug discovery? This analysis reveals publication trends related to given disease areas and provides methods to monitor areas in which scientific advances are likely to create new therapeutic opportunities. 30 October 2009
		New medicines to improve control and contribute to the eradication of malaria Recent advances in genome-based technologies and in in vitro screening of whole parasites have broadened the range of therapeutic targets and are accelerating the development of a new generation of treatments for both malaria control and eradication. 30 October 2009
		Development of universal antidotes to control aptamer activity A set of antidote molecules have been developed that are capable of counteracting the effects of an entire class of therapeutic agents based upon aptamers. 30 October 2009
		In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses Small interfering RNA synthetically linked to a CpG oligonucleotide agonist of toll-like receptor 9 targets and silences immunosuppressive genes and inhibits tumour growth in mouse models. 30 October 2009