Research highlights archive: November 2002

		Obesity: Dead end for NPY Y5-receptor antagonists? The neuropeptide Y5 receptor might not be a significant regulator of feeding behaviour. 29 November 2002
		Cancer prevention: Supermice Increasing p53 activity could be a viable cancer prevention strategy. 29 November 2002
		Human disease: A clear suspect The programmed cell death gene 1 (PCDC1) is associated with systemic lupus erythematosus (SLE). 29 November 2002
		Analgesics: Just what we wanted An alternative to opioids that could treat severe pain without risk of dependence and tolerance. 22 November 2002
		Apoptosis: Divide or die The E2F transcription factor has a key role in how oncogenes induce cell death. 22 November 2002
		HIV: Identity of CAF revealed After a 16-year search, researchers have finally identified the main component of CD8 antiviral factor (CAF), the soluble factor that suppresses HIV-1 replication. 22 November 2002
		Prion diseases: Toxic waste The studies that provide a startling new viewpoint to the true culprit for neurotoxicity in prion diseases. 15 November 2002
		Excitotoxicity: Blocking the pathway to excitotoxicity Researchers have found another option in the search for therapeutic advances for stroke. 15 November 2002
		Bone diseases: Having the cake and eating it A synthetic hormone replacement therapy that can increase bone mass and strength in mice without the side effects that could increase cancer risk. 15 November 2002
		Cardiovascular disease: macrophage LXRs inhibit atherosclerosis An important regulator of cholesterol metabolism and transport protects against atherosclerosis in mouse models. 1 November 2002
		Cancer genetics: it doesn't always take two One copy of the BLM gene predisposes humans and mice to colorectal cancer. 1 November 2002
		Protein folding: Folding forecast Computer simulations have accurately predicted a protein's structure from it's sequence. 1 November 2002