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Angiogenesis:
Recruitment drive
Vascular endothelial growth factor is important in tumour angiogenesis,
but is it essential that cancer cells themselves express VEGF?
A new study reveals all.
23 July 2004 |
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Human
genetics: Drawn into bad company
Two significant and nuch-needed strides have been made in the
molecular characterization of Huntington disease.
23 July 2004 |
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Nuclear
receptors: Growing concern for tamoxifen
Breast tumours that recur after treatment with tamoxifen might
result from a change in the effect of the drug that turns it
from an antagonist of the oestrogen receptor into an agonist
that promotes cancer cell growth.
23 July 2004 |
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Muscular
dystrophy: A LARGE dose of sugar
The discovery of an enzyme that can restore muscle function
could be sweet news for patients with muscular dystrophy.
9 July 2004 |
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A
study has thrown up a surprising link between circadian genes
and epilepsy, thanks to some knockout transgenic mice and a
vacuum cleaner.
9 July 2004 |
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Tumour
suppressors: Discrimination
How the cellular machinery discriminates between normal and
abnormal cell-cycle gene expression is now revealed.
9 July 2004 |
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Structural
biology: Not so crystal clear
Protein structures solved by X-ray crystallography might not
be as accurate as originally thought.
2 July 2004 |
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Tumour
suppressors: Happy couple
The lesser-known relative of p53 -- p73 -- might also be an
important aspect of tumour suppression.
2 July 2004 |
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T-cell
responses: Cutting out the middle man
Antigen-presenting cells are not always required to link innate
immune signals through Toll-like receptors to adaptive T-cell
responses.
2 July 2004 |
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