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MicroRNA losses in the frequently deleted region of 7q in SMZL

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References

  1. Mateo M, Mollejo M, Villuendas R, Algara P, Sanchez-Beato M, Martinez P et al. 7q31-32 allelic loss is a frequent finding in splenic marginal zone lymphoma. Am J Pathol 1999; 154: 1583–1589.

    Article  CAS  Google Scholar 

  2. Ruiz-Ballesteros E, Mollejo M, Rodriguez A, Camacho FI, Algara P, Martinez N et al. Splenic marginal zone lymphoma: proposal of new diagnostic and prognostic markers identified after tissue and cDNA microarray analysis. Blood 2005; 106: 1831–1838.

    Article  CAS  Google Scholar 

  3. Thieblemont C, Nasser V, Felman P, Leroy K, Gazzo S, Callet-Bauchu E et al. Small lymphocytic lymphoma, marginal zone B-cell lymphoma, and mantle cell lymphoma exhibit distinct gene-expression profiles allowing molecular diagnosis. Blood 2004; 103: 2727–2737.

    Article  CAS  Google Scholar 

  4. Gruszka-Westwood AM, Hamoudi R, Osborne L, Matutes E, Catovsky D . Deletion mapping on the long arm of chromosome 7 in splenic lymphoma with villous lymphocytes. Gene Chromosome Cancer 2003; 36: 57–69.

    Article  CAS  Google Scholar 

  5. Calin GA, Croce CM . MicroRNA signatures in human cancers. Nat Rev Cancer 2006; 6: 857–866.

    Article  CAS  Google Scholar 

  6. Calin GA, Ferracin M, Cimmino A, Di Leva G, Shimizu M, Wojcik SE et al. A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N Engl J Med 2005; 353: 1793–1801.

    Article  CAS  Google Scholar 

  7. Yu J, Wang F, Yang GH, Wang FL, Ma YN, Du ZW et al. Human microRNA clusters: genomic organization and expression profile in leukemia cell lines. Biochem Biophys Res Commun 2006; 349: 59–68.

    Article  CAS  Google Scholar 

  8. Pekarsky Y, Santanam U, Cimmino A, Palamarchuk A, Efanov A, Maximov V et al. Tcl1 Expression in Chronic lymphocytic leukemia is regulated by miR-29 and miR-181. Cancer Res 2006; 66: 11590–11593.

    Article  CAS  Google Scholar 

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Acknowledgements

We thank the skilled assistance of Lydia Sanchez (CNIO) with the immunohistochemical studies, and Yolanda Vicente (HVS) (CAO6/0006) for their excellent technical support. This work was partially supported by grants from the Ministerio de Ciencia y Tecnología (SAF2004-04286, SAF2005-00221), Fundación La Caixa, Ministerio de Sanidad y Consumo (FIS PI052621, FIS PI051623, INT06/062), Servicio de Salud de Castilla la Mancha (SESCAM #06047-00), and Consejería de Sanidad de la Junta de Comunidades de Castilla-La Mancha (#02031), Spain.

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Ruiz-Ballesteros, E., Mollejo, M., Mateo, M. et al. MicroRNA losses in the frequently deleted region of 7q in SMZL. Leukemia 21, 2547–2549 (2007). https://doi.org/10.1038/sj.leu.2404853

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