The author is in the Department of Biochemistry and Biophysics, Stockholm University, SE-10691 Stockholm, Sweden. gunnar@dbb.su.se
How are individual transmembrane helices in polytopic membrane proteins delivered from the Sec translocon into the lipid bilayer? A new study on the aquaporin-4 water channel shows that they move out of the translocon in succession but may linger nearby for an extended period of time.
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