The author is in the Department of Biochemistry 161, Radboud University Nijmegen, PO Box 9101, NL-6500 HB Nijmegen, The Netherlands. g.pruijn@ncmls.ru.nl
The exosome is a complex composed of 3'5' exoribonucleases involved in RNA processing and degradation. The first high-resolution structure of the exosome core reveals a doughnut-like arrangement of six RNase PH−type subunits.
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