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Alternative splicing: regulation without regulators

Nature Structural & Molecular Biology volume 16, pages 13–15 (2009)Cite this article

Alternative splicing is typically thought to be controlled by RNA binding proteins that modulate the activity of the spliceosome. A new study not only demonstrates that alternative splicing can be regulated without the involvement of auxiliary splicing factors, but also provides mechanistic insight into how this can occur.

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Figure 1: Traditional splicing regulation.
Figure 2: Regulation without regulators.

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  1. Brenton R. Graveley is in the Department of Genetics and Developmental Biology, University of Connecticut Stem Cell Institute, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, Connecticut 06030-3301, USA. graveley@neuron.uchc.edu,

    Brenton R Graveley

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Graveley, B. Alternative splicing: regulation without regulators. Nat Struct Mol Biol 16, 13–15 (2009). https://doi.org/10.1038/nsmb0109-13

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