At last, structures have been solved for different conformational states, facing in and facing out, for the same transporter protein of the major facilitator superfamily. The structural basis of alternating substrate access for binding and translocation can now be properly visualized.
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Henderson, P., Baldwin, S. This is about the in and the out. Nat Struct Mol Biol 20, 654–655 (2013). https://doi.org/10.1038/nsmb.2604
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DOI: https://doi.org/10.1038/nsmb.2604
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