The author is in the Department of Physical
Biochemistry, Max-Planck-Institute of Molecular Physiology,
Otto-Hahn-Str. 11, 44227 Dortmund,
Germany. goody@mpi-dortmund.mpg.de
Four recent studies demonstrate that closing of a cleft in the
myosin head is required for actin binding and nucleotide release. This
represents a major breakthrough in understanding actomyosin-based
motility.
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