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The anatomy of infidelity

Recent crystal structures of error prone DNA polymerases that bypass damage in DNA templates provide counterexamples to high fidelity polymerases.

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Figure 1: Comparison of error prone and high fidelity polymerases.

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Correspondence to Tom Ellenberger or Laura F. Silvian.

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Ellenberger, T., Silvian, L. The anatomy of infidelity. Nat Struct Mol Biol 8, 827–828 (2001). https://doi.org/10.1038/nsb1001-827

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