Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Year in Review
  • Published:

Prostate cancer in 2017

Advances in imaging

In the past year, the results of three studies in the field of prostate cancer imaging — the prostate MR imaging study (PROMIS), an analysis of the cost-effectiveness of various diagnostic strategies based on PROMIS data, and a retrospective analysis of a prostate-specific membrane antigen (PSMA)-directed PET radiopharmaceutical — have been published that could have lasting effects on clinical practice.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Ahmed, H. U. et al. Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS): a paired validating confirmatory study. Lancet 389, 815–822 (2017).

    Article  Google Scholar 

  2. Faria, R. et al. Optimising the diagnosis of prostate cancer in the era of multiparametric magnetic resonance imaging: a cost-effectiveness analysis based on the prostate MR imaging study (PROMIS). Eur. Urol. http://dx.doi.org/10.1016/j.eururo.2017.08.018 (2017).

  3. Afshar-Oromieh, A. et al. Diagnostic performance of 68Ga-PSMA-11 (HBED-CC) PET/CT in patients with recurrent prostate cancer: evaluation in 1007 patients. Eur. J. Nucl. Med. Mol. Imaging 44, 1258–1268 (2017).

    Article  Google Scholar 

  4. Moldovan, P. C. et al. What is the negative predictive value of multiparametric magnetic resonance imaging in excluding prostate cancer at biopsy? A systematic review and meta-analysis from the European Association of Urology Prostate Cancer Guidelines Panel. Eur. Urol. 72, 250–266 (2017).

    Article  Google Scholar 

  5. Delongchamps, N. B. et al. Prebiopsy magnetic resonance imaging and prostate cancer detection: comparison of random and targeted biopsies. J. Urol. 189, 493–499 (2013).

    Article  Google Scholar 

  6. Puech, P. et al. Prostate cancer diagnosis: multiparametric MR-targeted biopsy with cognitive and transrectal US-MR fusion guidance versus systematic biopsy — prospective multicenter study. Radiology 268, 461–469 (2013).

    Article  Google Scholar 

  7. Gillessen, S. et al. Management of patients with advanced prostate cancer: the report of the advanced prostate cancer consensus conference APCCC 2017. Eur. Urol. http://dx.doi.org/10.1016/j.eururo.2017.06.002 (2017).

  8. Vargas, H. A. et al. Localizing sites of disease in patients with rising serum prostate-specific antigen up to 1 ng/ml following prostatectomy: how much information can conventional imaging provide? Urol. Oncol. 34, 482.e5–482.e10 (2016).

    Article  Google Scholar 

  9. Nanni, C. et al. 18F-FACBC (anti1-amino-3-18F-fluorocyclobutane-1-carboxylic acid) versus 11C-choline PET/CT in prostate cancer relapse: results of a prospective trial. Eur. J. Nucl. Med. Mol. Imaging 43, 1601–1610 (2016).

    Article  CAS  Google Scholar 

  10. von Eyben, F. E. et al. 68Ga-labeled prostate-specific membrane antigen ligand positron emission tomography/computed tomography for prostate cancer: a systematic review and meta-analysis. Eur. Urol. Focus http://dx.doi.org/10.1016/j.euf.2016.11.002 (2016).

Download references

Acknowledgements

The authors thank Ada Muellner, MS, of Memorial Sloan Kettering Cancer Center, who helped edit the manuscript before submission.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Andreas G. Wibmer.

Ethics declarations

Competing interests

A.G.W. has received support from the Peter Michael Foundation. H.H. serves on the Board of Directors of Ion Beam Application (IBA), a role for which she receives annual compensation.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Wibmer, A., Vargas, H. & Hricak, H. Advances in imaging. Nat Rev Urol 15, 81–82 (2018). https://doi.org/10.1038/nrurol.2017.210

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrurol.2017.210

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing