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Genetics

Optic nerve genetics—more than meets the eye

Nature Reviews Neurology volume 6, pages 357–358 (2010)Cite this article

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Hereditary eye diseases can feature extraocular neurological complications, although such additional phenotypes can go undetected when a patient's visual defect is dramatic. A consortium has found that extraocular neurological phenotypes are common in patients with OPA1 mutation-related autosomal dominant optic atrophy, occurring in one-fifth of all such individuals.

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Authors and Affiliations

  1. Center for Ophthalmology and Visual Science, Lions Eye Institute, University of Western Australia, 2 Verdun Street, Nedlands, 6009, WA, Australia

    David A. Mackey

  2. Center for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, 32 Gisborne Street, East Melbourne, 3002, Vic, Australia

    Ian Trounce

Authors
  1. David A. Mackey
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  2. Ian Trounce
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Correspondence to David A. Mackey.

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The authors declare no competing financial interests.

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Mackey, D., Trounce, I. Optic nerve genetics—more than meets the eye. Nat Rev Neurol 6, 357–358 (2010). https://doi.org/10.1038/nrneurol.2010.77

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