Brief Communication abstract
Nature Neuroscience 10, 682 - 684 (2007)
Published online: 7 May 2007 | doi:10.1038/nn1905
Experience-dependent rescaling of entorhinal grids
Caswell Barry1,2,3,4, Robin Hayman3,4, Neil Burgess1,2 & Kathryn J Jeffery3,4
The firing pattern of entorhinal 'grid cells' is thought to provide an intrinsic metric for space. We report a strong experience-dependent environmental influence: the spatial scales of the grids (which are aligned and have fixed relative sizes within each animal) vary parametrically with changes to a familiar environment's size and shape. Thus grid scale reflects an interaction between intrinsic, path-integrative calculation of location and learned associations to the external environment.
- Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London WC1N 3AR, UK.
- Department of Anatomy, University College London, Gower St., London WC1E 6BT, UK.
- Institute of Behavioural Neuroscience, University College London, 26 Bedford Way, London WC1H 0AP, UK.
- Department of Psychology, University College London, 26 Bedford Way, London WC1H 0AP, UK.
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
RESEARCH
Hippocampal remapping and grid realignment in entorhinal cortexNature Letters to Editor (08 Mar 2007)
Microstructure of a spatial map in the entorhinal cortexNature Article (11 Aug 2005)