Specifying motor neurons: up and down and back to front
William A Harris
William Harris is at the Department of Anatomy, Cambridge University, Downing Street, Cambridge CB2 3DY, UK. harris@mole.bio.cam.ac.uk
A recent study in Nature shows that the columnar fate of motor neurons in the embryonic spinal cord is imposed by cross-repressive patterns of Hox-c expression. This Hox expression is in turn controlled by graded FGF signaling.
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