Sleep and circadian rhythms: do sleep centers talk back to the clock?
Christopher S Colwell
& Stephan Michel
The authors are at the Laboratory of Circadian Neurobiology, Department of Psychiatry, University of California, Los Angeles, Medical School, 760 Westwood Plaza, Los Angeles, California 90024, USA. ccolwell@mednet.ucla.edu
A homeostatic control mechanism that monitors and reacts to the need for sleep has been thought to function independently of the brain's circadian clock in previous studies. Now simultaneous recordings of sleep stages and electrical activity in the suprachiasmatic nucleus in behaving animals reveal feedback from sleep centers to the circadian pacemaker.
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