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From neuron to BOLD: new connections

Nature Neuroscience volume 4, pages 864–866 (2001)Cite this article

A recent paper in Nature directly compares fMRI with simultaneously recorded neural activity in the monkey, yielding new insights into the interpretation of BOLD contrast.

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Figure 1: Simultaneous neural and hemodynamic recordings from a cortical site showing transient neural response to a pulse stimulus of 24 seconds.
Figure 2: The BOLD response has larger amplitudes than expected from a linear response to a constant input across stimulus durations.
Figure 3: Normalized response amplitude of LFP, multi-unit activity and BOLD against contrast.

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Authors and Affiliations

  1. Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, 20892, Maryland, USA

    Peter A. Bandettini & Leslie G. Ungerleider

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  1. Peter A. Bandettini
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  2. Leslie G. Ungerleider
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Correspondence to Peter A. Bandettini or Leslie G. Ungerleider.

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Bandettini, P., Ungerleider, L. From neuron to BOLD: new connections. Nat Neurosci 4, 864–866 (2001). https://doi.org/10.1038/nn0901-864

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