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Synaptic vesicles really do kiss and run

A new study demonstrates that small synaptic vesicles exocytose dopamine through a flickering fusion pore almost exclusively, a process known as 'kiss-and-run' exocytosis. This process is driven by the need for efficient use of few synaptic vesicles.

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Figure 1: Exocytotic mechanisms for small synaptic vesicles.

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Wightman, R., Haynes, C. Synaptic vesicles really do kiss and run. Nat Neurosci 7, 321–322 (2004). https://doi.org/10.1038/nn0404-321

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