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Nature Neuroscience 9, 7 - 8 (2006)
doi:10.1038/nn0106-7

Monogamy: dopamine ties the knot

Scott Edwards & David W Self

The authors are in the Department of Psychiatry, the Seay Center for Basic and Applied Research in Psychiatric Illness, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9070, USA. david.self@utsouthwestern.edu

Prairie voles form lasting pair bonds with their mating partners after a single experience of sexual activity, and this reward-related learning depends on dopamine. A new paper reports that two dopamine receptor subtypes contribute differently to the initial formation of pair bonds and to their maintenance by the promotion of selective aggression toward alternative mates.

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Nature Neuroscience
ISSN: 1097-6256
EISSN: 1546-1726
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